Creating an intelligent security environment is one of the main trends in the activity of scientific organizations, where security technologies are a significant part of the product range. Organizations using these technologies, including critical infrastructure with built-in security systems, provide increased operational efficiency, guaranteeing readiness for action in emergency situations. For this purpose, standardized approaches are applied to determine the requirements for the development of security systems, according to the specifics of the organization, ensuring the prevention of any level of potential consequences of possible risk events, both in the structural objects of the organization and for the population in the adjacent territories. The author's intention is through this publication to present his experience in the application of modern standardized approaches ensuring the construction and operation of critical infrastructure security systems developed by scientific organizations in the conditions of key partnerships of the Competence Center.