Systemic Research Research Articles

Using Alternative Sources of Energy for Decarbonization: A Piece of Cake, but How to Cook This Cake?

Few analytical or research works claim that the negative impact of improper use of ASEs may be comparable with that of hydrocarbons and sometimes even greater. It has become a common view that "green" energy (ASE) is clean, safe and environmentally friendly (eco-friendly) in contrast with "black" energy (hydrocarbons). We analyzed 144 works on systemic and/or comparative research of the modern and prospective ASE: biofuels, hydrogen, hydropower, nuclear power, wind power, solar power, geothermal power, oceanic thermal power, tidal power, wind wave power and nuclear fusion power. We performed our analysis within the Spaceship Earth paradigm. We conclude that there is no perfect ASE that is always eco-friendly. All ASEs may be dangerous to the planet considered as a closed and isolated unit ("spaceship") if they are used in an inconsistent manner. This is not in the least a reason to deny them as prospective sources of energy. Using all ASEs in different proportions in various regions of the planet, where their harm to the planet and humanity can be minimized and, on the contrary, their efficiency maximized, would give humanity the opportunity to decarbonize the Earth, and make the energy transition in the most effective way.

Agriculture and food security under a changing climate: An underestimated challenge.

Pathways to eradicate global hunger while bending the curve of biodiversity loss unanimously suggest changing to less energy-rich diets, closing yield gaps through agroecological principles, adopting modern breeding technologies to foster stress resilience and yields, as well as minimizing harvest losses and food waste. Against the background of a brief history of global agriculture, we review the available evidence on how the global food system might look given a global temperature increase by 3°. We show that a moderate gain in the area suitable for agriculture is confronted with substantial yield losses through strains on crop physiology, multitrophic interactions, and more frequent extreme events. Self-amplifying feedback are unresolved and might lead to further losses. In light of these uncertainties, we see that complexity is underestimated and more systemic research is needed. Efficiency gains in agriculture, albeit indispensable, will not be enough to achieve food security under severe climate change.

The Concept of a Noble and a Perfect Person in Religious Philosophy

The formation of a noble and perfect person is the basis of social development. The ideas of nobility and perfection have evolved historically alongside human development. In the era of modern global processes and the fall of values, the concept of a noble and perfect person in religious philosophy does not lose its relevance. This article’s goal is to make clear the significance and essential characteristics of a noble and perfect person in religious philosophy. This article is based on the findings of numerous scientists who have investigated the issues raised by these concepts. The significance of comprehending the idea of a noble and perfect person from a theoretical standpoint is discussed in the article. We shall address each of these subjects in turn. First of all, we define the characteristics of a noble person and the role of Confucianism in defining the concept. The study revealed that a noble person should be an independent, moral, and unique individual. The primary features of a perfect person are then defined. It has been established that the perfect person is exemplary and distinguishable by ideality. Comparative analysis was used to study the scientific literature and produce the results. A descriptive approach was used to emphasize content analysis as well as systemic and historical research techniques. The article’s authors got to the conclusion that there are differences between what is meant by a noble person and what is meant by a perfect person. Key words: noble person, perfect person, being, humanity, Sufism.

The architecture of business centers in major cities of independent Kazakhstan

Introduction: The study aims to determine the main trends in the formation of business centers in Kazakhstan’s two largest cities, Almaty and Nur-Sultan, and to develop the main city planning and architectural recommendations for improving the network of business centers and their maintenance. Materials and Methods: The study’s systemic and complex research methodology allows it to look at business center issues from a variety of perspectives, including economic, socio-political, legislative, urban planning, and innovation. This approach allowed the architecture of business centers to be highlighted as a dynamic, interrelated process that represents the state’s economic power and prestige. Results and Discussion: The identification of trends in the development of business centers as the main type of commercial real estate is intrinsically linked to their natural qualitative growth and structural metamorphoses, transforming future cities into business cities, business parks, business incubators, and eco-towns. Conclusions: The study revealed that a specific feature of the business center is the distinction in its space-planning structure of the recreational and communicative block of premises and rooms into a separate independent functional block, which, both locally and dispersed spatially, carries an ideological and logical practical load and is a functional space for a multi-purpose business building.

Triphala: Its pharmacological values and new perspectives

Medicinal plants, with tremendous elementary and therapeutic importance, are the gift to humanity. Triphala is widely used in the traditional Indian system of medicine. It's an antioxidant-rich polyherbal formulation and possesses diverse beneficial properties. It's necessary to corroborate the consistency of blending or combining in attribute balance. As per Ayurvedic Formulary of India (AFI) it's prepared by combining a 1:1:1 mixing of ground dry fruits, called as myrobalans. It shows immune modulatory properties and helps in improving the body's weaponry. Recent studies suggest that triphala possesses anti-mutagenic, radio protecting and antioxidant activity and beneficial in diseases conditions. However, serious efforts are required in systemic research to spot, isolate and evaluate the chemical constituents for nutritional and therapeutic potentials.

SPC RAS — 45 Years of Scientific Activity

45 years ago, had started the history of the St. Petersburg Institute for Informatics and Automation of the Russian Academy of Sciences (SPIIRAS), when by the Order of the Council of Ministers of the USSR dated December 19, 1977 and by the Decree of the Presidium of the Academy of Sciences of the USSR dated January 19, 1978, the Leningrad Research Computer Center of the USSR Academy of Sciences (LRCC) had been established, that later in 1985 was transformed by the decision of the Presidium of the USSR Academy of Sciences into the Leningrad Institute for Informatics and Automation of the USSR Academy of Sciences (LIIAS), then in 1991, as stipulated by the return to the city of its historical name, the Institute acquired its current name of SPIIRAS. By its 45th anniversary, the Institute for Informatics (LRCC, LIIAS, SPIIRAS), having united with five leading academic entities of the North-West of Russia, in 2020 turned into the St. Petersburg Federal Research Center of the Russian Academy of Sciences (SPC RAS). With no exaggeration, a distinctive mark of the SPC RAS scientific team is systemic interdisciplinary research. The fundamental results received by the SPC RAS scientists in computer science, cybernetics, artificial intelligence, robotics, security, ecology, agriculture and innovation and investment development of territories fit well in forming the applied solutions that regard the digital transformation of agroecological production, strengthening food, environmental and information security of citizens of our country.

Konektoru lietojums latviešu zinātniskajos rakstos

The means of creating the cohesion of the text have not been looked at in the research of Latvian scientific texts. Since it is important within the context of academic writing and language learning, the purpose of this article is to update the research on the linkage of propositions in Latvian scientific texts and, having studied the usage of various linguistic approaches, present the results of the feasibility study on the use of linguistic means, while also identifying issues that need further research. The research carried out is based on an analysis of the cohesion tools in two social and natural science articles, followed by quantitative research of the texts of six scientific disciplines (600 texts in total) in order to selectively examine the frequency of use of connectors and the differences in texts of different fields of science using AntConc software. The results of the study show that the binding elements that make up the cohesion of the text are a heterogeneous group in terms of belonging to different word classes, as already concluded in previous text syntax studies, as well as in relation to the use of grammatical forms (e.g. future form, participles). Part of the established binding elements of proposition (pronouns and nouns) relate mainly to the provision of referential identity, while others, on the other hand, are signs of an interactive metadiscourse and implement various semantic attitudes that allow them to be interpreted in this context. According to the results of the analysis on the frequency of use of connectors, there are differences between the texts of different fields of science. A further systemic study of these could form the basis for determining the specific characteristics of scientific reasoning by means of a quantitative method. Further systemic research of connectors could be partly based on the analysis of semantic attitudes carried out in syntax research (Latvian and other languages), the basis of text linguistics in cohesion research, as well as research on the interactive features of metadiscourse. At the same time, in connection with the analysis of semantics, text, discourse, and metadiscourse, it is necessary to focus on the development of the terminology of the topic in Latvian in the future. This, combined with a systemic continuation of research in the future, would have a practical role in the development of the classification of connectors, a catalogue, a lexicographic description, and teaching tools for academic writing.

Obesity, Diabetes, and Cardiovascular Risk Burden in Systemic Lupus Erythematosus: Current Approaches and Knowledge Gaps-A Rapid Scoping Review.

Obesity, diabetes mellitus, and cardiovascular risk are real challenges in systemic lupus erythematosus (SLE) clinical practice and research. The evidence of the burden of these health problems in SLE patients is determined by the methods used to assess them. Therefore, the aim of this scoping review is to map current approaches in assessing obesity, diabetes mellitus, and cardiovascular risk burden in SLE patients and to identify existing knowledge gaps in this field. This rapid scoping review was conducted according to the Joanna Briggs Institute methodology and identified 274 articles, of which 73 were included. Most studies were conducted at European institutions and patients were recruited from specialist hospital clinics, the majority of whom were women. The burden of obesity and diabetes mellitus for SLE patients was assessed mainly in terms of prevalence, impact on disease activity, and cardiometabolic risk. The burden of cardiovascular risk was assessed using multiple approaches, mainly imaging and laboratory methods, and risk factor-based scores, although there is great heterogeneity and uncertainty between the methods used. This review highlights the importance of improving and standardizing the approach to obesity, diabetes, and cardiovascular risk in SLE patients through a holistic assessment that includes lifestyle, clinical, biological, and social aspects.

2022 Chinese guideline for the management of pregnancy and reproduction in patients with systemic lupus erythematous

Systemic lupus erythematosus (SLE) is an autoimmune disease that affects women of childbearing age. With the improvement of diagnosis and treatment, the survival rate of SLE patients has improved significantly, but pregnancy is still an important challenge for SLE patients. It is urgent to strengthen the reproductive and pregnancy management of SLE patients and standardize the peri-gestational monitoring and treatment of SLE patients. This guideline is jointly sponsored by the National Clinical Research Center for Dermatologic and Immunologic Diseases (NCRC-DID), Chinese Systemic Lupus Erythematosus Treatment and Research Group (CSTAR), and Chinese Research Committee of pregnancy and reproduction in autoimmune rheumatic diseases (CHOPARD). Guided by clinical problems, after several rounds of clinical and methodological expert demonstration and selection, 13 clinical problems that need to be solved are finally formed, based on evidence-based medical evidence and expert opinions, guideline recommendations are given. The aim is to improve the pregnancy success rate and reduce the maternal and infant mortality rate in SLE patients.

청소년 비자살적 자해(NSSI) 과정과 멈춤 경험에 관한 연구

At the adolescent’s NSSI(Non-Suicidal Self-Injury) is getting more risky and more contagious recently in our society and becoming a severe social problem, we need to conduct systemic and empirical research on it. The therapy intervention in NSSI must be different from the therapy intervention in Suicidal self-injury. The purpose of this study was to examine the mediation effects of unconditional self-acceptance and must handle the psychological meaning in context acts of adolescents with NSSI experience. This study aims to understand NSSI through adolescent’s experiences of NSSI and develop a proper therapy intervention. For this purpose, 9 adolescents who are thought to have enough NSSI experience were interviewed in depth and the data from these interviews and research notes were analyzed by using the grounded theory. The results of this analysis revealed 93 concepts, 36 sub categories, 15 superordinate categories and “a product of subjective perception of distressing emotional experience” as the phenomenons. Though external factors and internal factors effect NSSI, the subjective perception of external experience and internal experience is essential for occurrence of NSSI. Based on these result, implications and limitations of the present study are discussed.

Consumer logistics: a systematic literature review

ABSTRACT The research field of Consumer Logistics (CL), initiated by Granzin and Bahn, deals with consumer logistics participation in product handling, from the point of acquisition to destruction. Research into CL stems from the premise that consumers’ logistics activities resemble those of businesses closely. With consumers’ increasingly active logistics role in acquiring goods or services, transporting, and storing goods, but also disposing or getting rid of them, this field is receiving growing attention. However, there is no general view or synthesis of this fragmented field, located at the interface of different disciplines. With the objective of investigating current knowledge, we conducted a systematic literature review that analyzes 155 articles on CL spanning the last 32 years (1990–2022). Based on an analysis of the research themes, the article summarises and maps CL research, highlighting five areas of interest: 1) consumers’ choice of physical channel, 2) consumer transportation, 3) consumer storage, 4) systemic consumer logistics and 5) consumer outbound logistics. The article provides the first interdisciplinary synthesis of the fragmented CL literature and concludes with some suggestions to stimulate more systemic and sustainable CL research in the future.

Ukrainian pop song: development trends

The purpose of the article is to determine the peculiarities of the formation and development of the Ukrainian pop song. Methodology. In achieving this goal, the following research methods were applied: comparison, systematization, analysis, and generalization of the problem studied. The scientific novelty of the research lies in highlighting the main trends in the development of the modern Ukrainian pop song. Conclusions. Analysis of modern scientific literature devoted to the problem of the development of Ukrainian pop songs has shown an insufficient amount of systemic research in the field of national culture and art history. As for the modern Ukrainian song stage, it is not reflected in scientific research, although it is popular now. It has been proven that in Ukraine over the past few years, quite favorable conditions have been created for the development of young performers, and the Ukrainian pop song takes leading places in the European musical space. The article does not exhaust all issues related to Ukrainian songwriting. Further research on this topic can be aimed at studying the activities of individual modern Ukrainian pop performers, their creativity.
 Key words: Ukrainian pop song, development trends, periodization, pop, Pop performers.

Effect of entecavir and tenofovir disoproxil fumarate on hepatocellular carcinoma in subjects with chronic hepatitis B: a meta-analysis

BackgroundA meta-analysis was made to assess the impact of entecavir comparison with tenofovir disoproxil fumarate as nucleos(t)ide analogue on hepatic cellular carcinoma (HCC). The study had subjects with chronic hepatitis B virus (HBV). Systemic research was done for all studies concerned with our topic till the date (March 2022). We included 19 studies in which 27,618 subjects participated. All subjects included were diagnosed with chronic HBV at the beginning of the study. A total of 15,734 subjects from the overall 27,618 were medicated with entecavir; however, 11,884 subjects were on tenofovir disoproxil fumarate. We calculated the odds ratio (OR) with confidence intervals (CIs) of 95% to evaluate the impact of entecavir and tenofovir disoproxil fumarate on HCC in subjects with chronic HBV by applying a dichotomous approach with a random or fixed-effect model.ResultsChronic HBV subjects treated with entecavir showed a higher significant biochemical response than those treated with tenofovir disoproxil fumarate (OR 1.39; 95% CI 1.21–1.60, at p < 0.001). Also, no significant difference was detected with entecavir compared to tenofovir disoproxil fumarate concerning the occurrence of hepatic cells cancer (OR 1.26; 95% CI 0.96–1.67, p = 0.10), virological response (OR 0.89; 95% CI 0.63–1.25, p = 0.49), and seroconversion (OR 1.27; 95% CI 0.76–2.14, p = 0.37).ConclusionsThe use of entecavir resulted in a significantly higher biochemical response; nevertheless, it did not show any significant variation concerning the occurrence of hepatic cancer, virological response, or serological conversion compared to tenofovir disoproxil fumarate in chronic HBV subjects. So, results interpretation needs to be carried out carefully owing to the limited number of studies included in specific comparisons, e.g., serological conversion.

Small-animal blood exchange is an emerging approach for systemic aging research.

We describe a small-animal blood exchange approach developed for aging research as an alternative to heterochronic parabiosis or plasma injections. In parabiosis, animals are surgically coupled, which has several disadvantages, including difficulty controlling experimental procedure, the effects of shared organs, environmental enrichment from jointly exploring the housing enclosure, involuntary exercise and an imprecise onset of blood sharing. Likewise, in plasma injections, the added volumes need to be small, and there is little flexibility in changing the relative contributions of ectopic to endogenous blood components. These factors complicate the conclusions and interpretations, including the identification of key mechanisms and molecular or cellular determinants. Our approach, where blood is exchanged between animals without them being surgically coupled, is less invasive than parabiosis. The percentage of exchanged blood or other exchanged fluids is known and precise. The age of plasma and cells can be mixed and matched at all desired relative contributions to the endogenous systemic milieu, and the onset of the effects can be accurately delineated. In this protocol, we describe the preparatory and animal surgery steps required for small-animal blood exchange in mice and compare this process with parabiosis and plasma injections. We also provide the design, hardware and software for the blood exchange device and compare automated and manual exchange methods. Lastly, we report mathematical modeling of the dilution of blood factors. The fluid exchange takes ~30 min when performed by a well-trained biomedical scientist; the entire process takes ~2 h.

Evaluating Role of Arthrocentesis in Management of Internal Derangement of TMJ

Background: Concerning the management of TMJ the complex anatomy of TMJ plays a vital role since it has its components that attached the most versatile part of human body. It has its several components performing and aiding in multitude of functions(1). Each instance of TMD is different and complex, thus diagnosis involves a thorough examination of the individual patient's history and symptoms as well as a range of methods. Objective: The objective of this study was to evaluate the role of arthrocentesis in management of internal derangement of TMJ Methodology: In order to access the relevant research articles a systemic research was conducted via three data bases including PubMed, Google Scholar and web of science.

“Feminism is Intersectional”: Interview with Evan Imber-Black, PhD on Feminism and Marriage and Family Therapy

ABSTRACT Evan Imber-Black, Ph.D. is a prominent figure and has made major contributions in the field of family therapy since the 1980s. Currently, she serves as a Professor and the Program Director of the MFT Program at Mercy College in Dobbs Ferry, New York. Dr. Imber-Black is internationally recognized for her scholarly commitment to systemic research and therapy. She served as editor-in-chief of Family Process and has authored many original papers and books that have influenced models of practice, including family rituals and family secrets. Dr. Imber-Black’s career demonstrates the power of leadership in family therapy, and that within this field one can succeed and impact families through all sectors of systemic therapy: clinical practice, research, teaching, and mentorship. This interview explored the history of a powerful woman who rose to the ranks of a boy’s club in the MFT field and discusses the gender and racial/ethnic disparities within the field today. She shared her perspective of intersectionality in contemporary feminist family therapy practice and education.

JINOYAT TARKIBI TO‘G‘RISIDAGI TA’LIMOTNING SHAKLLANISHI VA RIVOJLANISHIDA JINOYAT OBYEKTIV TOMONI BELGILARINING O‘RNI: QIYOSIY TAHLIL

This article widely uses logical, systemic, logical-legal, and comparative-legal research methods. In particular, first of all, the formation of the doctrine of the structure of crime and its stages of historical development are described in detail. Also, the role of the objective side of the crime in the formation of the doctrine of the corpus delicti, the views expressed by scientists in the theory of criminal law are considered, after which individual subjective signs of the corpus delicti and their features are classified, developed on the basis of the signs of the objective side of the classical German school of criminal law. At the same time, the significance of the signs of the objective side of the crime in the development of the existing concept of corpus delicti in the modern theory of criminal law is described. In this article, based on the deduction method, the work reflects the concept of corpus delicti, taking the objective side of the crime as the basis of this doctrine, that is, corpus delicti (in Roman law) - the composition of the law (classical German law) - the concept of corpus delicti (50-60 years of the XIX-XX centuries). In addition, the article considers the specifics of the objective side of the crime in the formation and development of the doctrine of the corpus delicti and the concept of the corpus delicti, their specific criminal significance, as well as theoretical and practical problems associated with the elements of the corpus delicti, crime as the only basis for responsibility given in the Criminal Code of the Republic of Uzbekistan. At the same time, the criminal legislations of the Russian Federation, Belarus and Moldova were analyzed, specific proposals and recommendations were developed to improve the criminal legislation of the Republic of Uzbekistan.

AutoMorph: Automated Retinal Vascular Morphology Quantification Via a Deep Learning Pipeline.

PurposeTo externally validate a deep learning pipeline (AutoMorph) for automated analysis of retinal vascular morphology on fundus photographs. AutoMorph has been made publicly available, facilitating widespread research in ophthalmic and systemic diseases.MethodsAutoMorph consists of four functional modules: image preprocessing, image quality grading, anatomical segmentation (including binary vessel, artery/vein, and optic disc/cup segmentation), and vascular morphology feature measurement. Image quality grading and anatomical segmentation use the most recent deep learning techniques. We employ a model ensemble strategy to achieve robust results and analyze the prediction confidence to rectify false gradable cases in image quality grading. We externally validate the performance of each module on several independent publicly available datasets.ResultsThe EfficientNet-b4 architecture used in the image grading module achieves performance comparable to that of the state of the art for EyePACS-Q, with an F1-score of 0.86. The confidence analysis reduces the number of images incorrectly assessed as gradable by 76%. Binary vessel segmentation achieves an F1-score of 0.73 on AV-WIDE and 0.78 on DR HAGIS. Artery/vein scores are 0.66 on IOSTAR-AV, and disc segmentation achieves 0.94 in IDRID. Vascular morphology features measured from the AutoMorph segmentation map and expert annotation show good to excellent agreement.ConclusionsAutoMorph modules perform well even when external validation data show domain differences from training data (e.g., with different imaging devices). This fully automated pipeline can thus allow detailed, efficient, and comprehensive analysis of retinal vascular morphology on color fundus photographs.Translational RelevanceBy making AutoMorph publicly available and open source, we hope to facilitate ophthalmic and systemic disease research, particularly in the emerging field of oculomics.

Sculpting the interpersonal: towards a social semiotic framework for analysing interpersonal meaning in statues

The underlying question of this article is ‘how do statues convey interpersonal meaning?’ To answer this question, the authors briefly critically examine the current social semiotic analytical framework for statues and develop a revised framework for analysing interpersonal meaning in which features from Kress and van Leeuwen’s Reading Images: The Grammar of Visual Design (2006) and selected features from O’Toole’s framework from The Language of Displayed Art (2011) for analysing sculpture are integrated. These features are also extended and/or complemented by incorporating features obtained from research into the fields of gesture, body language and facial expression. Further, in keeping with Systemic Functional Linguistic-inspired research, system networks are used to map out the potential material and semantic (interpersonal) features for figurative statues and to present possible configurations among these features. Although the focus of this article is on interpersonal meaning, it is acknowledged that within a social semiotic approach, there is an interdependency among interpersonal, experiential (representational) and textual (compositional) meanings, and that these configure within a specific context of situation. This interdependency is only briefly attended to in the article itself, but the proposed framework provides a starting point for developing an account of the way that interpersonal features and their realizations in statues may configure with representational and compositional features and their realizations. With the current world focus on statues and their sometimes controversial social meanings, this article offers a timely opportunity for a range of users such as social semioticians or art educators and students to consider, through a systematic analytical framework, the way in which statues may relate interpersonally with viewers, and provides a key step towards accounting for the way that configurations of interpersonal, representational and compositional features may construe contextual tensions in relation to the overall message conveyed by a statue.

Najnowsze metodologie badawcze w lingwistyce kontaktu i automatyczna ekscerpcja anglicyzmów

The paper presents the newest research methodologies used in the analysis and description of foreign lexical loans, such as the usage-based approach, experimental set-ups, as well as corpus-assisted research that includes automatic identification and excerption of unassimilated loanwords. The usage-based approach and experimental design spring from the revised perception of linguistic borrowing in contact linguistics, seen now as a social act, in which the recipient language speakers play the main role by fulfilling their nominal and expressive needs through conscious lexical choices. This type of research is also possible due to large electronic corpora equipped with the latest data processing tools that enable the analysis of borrowed material in authentic contexts. Rooted in the onomasiological-cognitive theoretical background and assuming a socio-pragmatic perspective, the presented methodologies allow for the analysis of those areas within linguistic borrowing that in structural and systemic research were neglected or unanalysable