ABSTRACT This paper presents a learning- and scenario-based model predictive control (MPC) design approach for systems modelled in the linear parameter-varying (LPV) framework. Using input-output data collected from the system, a state-space LPV model with uncertainty quantification is first learned through the variational Bayesian inference Neural Network (BNN) approach. The learned probabilistic model is assumed to contain the true dynamics of the system with a high probability and is used to generate scenarios that ensure safety for a scenario-based MPC. Moreover, to guarantee stability and enhance the performance of the closed-loop system, a parameter-dependent terminal cost and controller, as well as a terminal robust positive invariant set are designed. Numerical examples will be used to demonstrate that the proposed control design approach can ensure safety and achieve desired control performance.