The article investigates the anti-surge protection systems and mathematical modeling of systems of gas compressor units on the basis of centrifugal compressors with anti-surge valve or baypass, and a mixed protection system. The review of existing systems, surge protection of gas compressor units, which revealed a number of shortcomings when using antisurge valve or baypass system. The proposed mixed system of surge protection with simultaneous use of surge valve and baypass system. The proposed sequence of the mixed system of surge protection. The above block diagram of an electromechanical system centrifugal compressor – anti-surge valve - direct current motor with an automatic control system. Obtained by use of transient surge valve baypass and mixed anti-surge system. These conclusions underline the relevance of the research and energy efficiency centrifugal compressor anti-surge protection system.