Subsequent Loading Research Articles

Investigation of Phase Transformation and Fracture Pattern as a Result of Long-Term Chewing Simulation and Static Loading of Reduced-Diameter Zirconia Implants.

While zirconia implants exhibit osseointegration comparable to that of titanium, concerns arise regarding low-temperature degradation and its potential impact on fracture strength. This study investigated the phase transformation and fracture characteristics of zirconia dental implants after aging through chewing simulation and subsequent static loading. The experimental setup involved 48 one-piece monobloc zirconia implants with diameters of 3.0 mm and 3.7 mm that had straight or angled abutments, with crown restorations, which were divided into six groups based on intraoral regions. The specimens underwent chewing simulation equal to five years of oral service, which was followed by static loading. Statistical analyses were performed for the data obtained from the tests. After dynamic and static loadings, the fractured samples were investigated by Raman spectroscopy to analyze the phase composition and micro-CT to evaluate fracture surfaces and volume changes. According to the results, narrow-diameter zirconia implants have low mechanical durability. The fracture levels, fracture patterns, total porosity, and implant fracture volume values varied according to the implant diameter and phase transformation grade. It was concluded that phase transformation initially guides the propagation of microcracks in zirconia implants, enhancing fracture toughness up to a specific threshold; however, beyond that point, it leads to destructive consequences.

Hybrid rehabilitation of 3D RC beam-column joints using UHP-HFRC and FRP wrapping: Experimental evaluation and theoretical analysis

Beam-column joints are crucial elements in reinforced concrete (RC) structures subjected to seismic loading, as they are vulnerable elements prone to significant damage during earthquakes. Due to extensive structural damage, various methods have been developed to strengthen beam-column joints. However, research on rehabilitation and repair methods has been limited, with most studies focusing on 2-D joints and overlooking the confinement effect of corner beams on the joint core. This study aims to investigate novel hybrid rehabilitation systems, including ultra-high performance hybrid fiber-reinforced concrete (UHP-HFRC) and fiber-reinforced polymer (FRP) systems, alongside embedding reinforcement into heavily damaged 3-D beam-column joints subjected to pre-cyclic loading and subsequent cyclic loading. Parameters related to hysteresis response were obtained and discussed, such as ductility, lateral stiffness, dissipated energy, equivalent hysteresis damping, and pinching ratio of the tested specimens. The experimental findings revealed that utilizing an FRP and UHP-HFRC hybrid rehabilitation system enhanced ductility, dissipated energy, and lateral stiffness of heavily damaged joints by 25 %, 73 %, and 81 %, respectively, compared to the undamaged reference specimen. Additionally, a simplified design model was developed to predict the shear resistance of beam-column joints, incorporating principles of strut-and-tie. The theoretical design model was also validated against the experimental database, demonstrating a good accuracy with MV and COV of 0.97 and 13 %, respectively.

Histamine synthesis and transport are coupled in axon terminals via a dual quality control system

Monoamine neurotransmitters generated by de novo synthesis are rapidly transported and stored into synaptic vesicles at axon terminals. This transport is essential both for sustaining synaptic transmission and for limiting the toxic effects of monoamines. Here, synthesis of the monoamine histamine by histidine decarboxylase (HDC) and subsequent loading of histamine into synaptic vesicles are shown to be physically and functionally coupled within Drosophila photoreceptor terminals. This process requires HDC anchoring to synaptic vesicles via interactions with N-ethylmaleimide-sensitive fusion protein 1 (NSF1). Disassociating HDC from synaptic vesicles disrupts visual synaptic transmission and causes somatic accumulation of histamine, which leads to retinal degeneration. We further identified a proteasome degradation system mediated by the E3 ubiquitin ligase, purity of essence (POE), which clears mislocalized HDC from the soma, thus eliminating the cytotoxic effects of histamine. Taken together, our results reveal a dual mechanism for translocation and degradation of HDC that ensures restriction of histamine synthesis to axonal terminals and at the same time rapid loading into synaptic vesicles. This is crucial for sustaining neurotransmission and protecting against cytotoxic monoamines.

Superhydrophilic and Underwater Superaerophobic Dual-Function Peony-Shaped Selenide Micro-nano Array Self-Supported Electrodes for High-Efficiency Overall Water Splitting Driven by Renewable Energy.

With the intensification of global environmental pollution and resource scarcity, hydrogen has garnered significant attention as an ideal alternative to fossil fuels due to its high energy density and nonpolluting nature. Consequently, the urgent development of electrocatalytic water-splitting electrodes for hydrogen production is imperative. In this study, a superwetting selenide catalytic electrode with a peony-flower-shaped micronano array (MoS2/Co0.8Fe0.2Se2/NixSey/nickel foam (NF)) was synthesized on NF via a two-step hydrothermal method. The optimal catalytic activity of cobalt-iron selenide was achieved by adjusting the Co/Fe ratio. The intrinsic catalytic activity of the electrodes was enhanced by incorporating transition metal selenides, which then served as a precursor for the subsequent loading of MoS2 nanoflowers on the surface to fully expose the active sites. Furthermore, the superwetting properties of the electrode accelerated electrolyte penetration and electron/mass transfer, while also facilitating bubble detachment from the electrode surface, thereby preventing "bubble shielding effect". This resulted in superior oxygen evolution reaction (OER) and hydrogen evolution reaction (HER) performance, as well as overall water splitting capabilities. In a 1.0 M KOH solution, the electrode required only 166 and 195 mV overpotential to achieve a current density of 10 mA cm-2 for OER and HER, respectively. When functioning as a bifunctional catalytic electrode, only 1.60 V of voltage was necessary to drive the electrolyzer to reach a current density of 10 mA cm-2. Moreover, laboratory simulations of wind and solar energy-driven water splitting validated the feasibility of establishing a sustainable energy-to-hydrogen production chain. This work provides new insights into the preparation of low-overpotential, high-catalytic-activity superhydrophilic and underwater superaerophobic catalytic electrodes by rationally adjusting elemental ratios and exploring changes in electrode surface wettability.

Low-cycle fatigue behaviour of concrete-filled double skin steel tubular (CFDST) members for wind turbine towers

Wind energy has the advantages of being clean and renewable. Wind turbine towers endure horizontal cyclic loads that could influence the performance of entire structure. To clarify the low-cycle fatigue behaviour of concrete-filled double skin steel tubular (CFDST) members, a total of 16 specimens were experimented. The hollow, slenderness, and axial compression ratios are specifically designed to clarify the effects on performance under constant amplitude loading and hysteretic loading conditions. The typical failure modes under both loading conditions and the relationship between loop strain, loop bearing capacity, loop energy dissipation, cycle number, and various degradation indices were analysed. Studies indicate that the failure mode under low-cycle fatigue loading is mainly local deformation, which includes transverse fracture occurring at the region between the steel tube and ribbed stiffener, the crushing concrete. Fatigue specimens with different amplitudes exhibit varying shapes of hysteresis responses. Higher amplitudes could enhance damage and significantly reduce fatigue life. Increasing the hollow and axial compression ratios boosts the energy dissipation capacity, and decreasing the slenderness ratio enhances the lateral resistance. A 2 % constant amplitude preload intensifies the degradation of bearing capacity and energy dissipation under subsequent constant amplitude loading.

Model-free chemomechanical interfaces: History-dependent damage under transient mass diffusion

This paper presents a data-driven framework based on distance functional for chemo-mechanical cohesive interfaces to capture transient diffusion and resulting interfacial damage evolution. The framework eliminates reliance on complex constitutive models and phenomenological assumptions, especially avoiding the coupling tangent terms with a given material database. The interfacial chemical potential and its jumps are used to expand the phase space for describing the chemical states of interfaces. Subsequently, a novel chemo-mechanical distance norm, including traction-separation pair, interfacial chemical potential-concentration pair and corresponding chemical potential jump-flux pair, is presented. Momentum conservation law for interfacial tractions and mass conservation law for interfacial concentration are enforced via Lagrange multipliers. For tracking the history-dependent state of the interface damage, an internal variable, termed interface integrity, is introduced to condition the interfacial database and manage the subsets mapping strategies, following physically motivated evolution constraints. Numerical examples are conducted to investigate the efficiency and capability of the present framework. A monotonic loading test validates a good numerical convergence relative to the number of data points. Subsequent cyclic loading simulations, compared with the reference solutions, show that the algorithm is well suitable to predict the history-dependent interface damage evolution under complex loading paths. Finally, the chemo-mechanically coupled examples capture phenomena such as interfacial swelling and interface degradation induced by transient diffusion and stress-driven diffusion. The current work provides a promising tool for understanding chemo-mechanical behaviors of interfaces within heterogeneous composites.

Oral Administration of Berberine Hydrochloride Based on Chitosan/Carboxymethyl-β-Cyclodextrin Hydrogel.

In this study, a novel oral formulation of berberine hydrochloride (BBH) hydrogel was successfully synthesized through physical cross-linking using chitosan (CS) and carboxymethyl-β-cyclodextrin (CMCD). The characterization results confirmed the successful synthesis of the CS/CMCD hydrogel and the subsequent loading of BBH into this composite (CS/CMCD/BBH) was effectively accomplished. The BBH was used as a model drug and the resulting hydrogel demonstrated a sustained drug release profile. In addition to its improved solubility and sustained release characteristics, the hydrogel exhibited excellent antibacterial activity against common pathogens such as Escherichia coli (E. coli), Staphylococcus aureus (S. aureus), and Candida albicans (C. albicans). Additionally, in vitro studies indicated that the hydrogel was not cytotoxic to NIH3T3 and HaCaT cells, suggesting its safety for biomedical applications. This lack of cytotoxic effects, combined with the mechanical strength, solubility improvements, and antibacterial properties of the hydrogel, positions the CS/CMCD/BBH hydrogel as a promising candidate for the effective oral delivery of BBH. By addressing the solubility and delivery challenges of BBH, this hydrogel offers a viable solution for the oral administration of BBH, with potential applications in various biomedical fields.

Experimental study of poromechanical behavior of Callovo-Oxfordian claystone in undrained triaxial compression and extension tests

The Callovo-Oxfordian (COx) claystone is selected as the host rock in the French project for geological disposal of radioactive waste. In its initial state, the host rock is fully saturated. Due to the low permeability, the pore fluid pressure can locally evolve in a quasi undrained condition due to subsequent mechanical and thermal loading, and then significantly affects deformation and cracking process of geological barrier. Most previous studies were carried out in quasi drained conditions or with constant pore pressure. Poromechanical behavior of COx claystone in undrained condition has been so far rarely investigated. In the present work, we carry out a new series of laboratory tests. Two representative loading paths are considered: triaxial compression with constant confining pressure and triaxial extension with constant mean stress. The variations of strain and pore pressure are measured during the tests. It is found that the poromechanical behavior of the claystone is clearly affected by loading path. The failure strength is higher in triaxial compression than in extension. The evolution of pore fluid pressure is correlated with volumetric strain. Compared with the results obtained in drained tests, it seems that the Terzaghi effective stress can be used for the description of pore fluid pressure effect on failure strength.

The influence of initial static shear on the torsional performance of BFRP bars-RC beams with different sizes

To reveal the influence of the initial static shear on the torsional performance of Basalt Fiber Reinforced Polymer Bars-Reinforced Concrete (BFRP bars-RC) beams, in this study, 52 BFRP bars-RC beam models with geometric similarity using a three-dimensional mesoscale numerical simulation method were established. The effects of initial shear static loadings (F0 = 0, 0.25Vu, 0.5Vu, and 0.75Vu) on the failure modes, torsional strength, ductility, and size effect of BFRP bars-RC beams under various equivalent strain rates were quantitatively analyzed. The results show that, regardless of whether the beams have initial damage, their load-bearing capacity and deformation ability increase as loading strain rates increase. For beams with initial damage, the increased degrees in load-bearing capacity relative to their respective initial static shear decreases as the initial static shear level increases but then increases as the subsequent loading strain rate increases. Increasing the beams’ initial damage degree makes the beams’ ductility worse. In addition, the more severe the beams’ initial damage, the more significant the strength size effect. However, increasing the strain rate can weaken the beams’ strength size effect.

Temporal Effect of CYP3A4/5 Induction on Ticagrelor's Pharmacodynamic Effects: A Case Series.

Ticagrelor is contraindicated in combination with cytochrome P450 3A4 and 3A5 enzyme (CYP3A4/5) inducers due to increased clearance, causing diminished antiplatelet effects. The emergent nature of acute coronary syndromes (ACS) may preclude scrutinization of home medications before P2Y12 inhibitor administration. The purpose of this case series is to establish the temporal impact of CYP3A4/5 enzyme induction on ticagrelor's pharmacodynamic effect by utilizing VerifyNow platelet aggregation studies. This was a retrospective case series of three patients who were taking a CYP3A4/5-inducing medication and loaded with ticagrelor for ACS. The duration of ticagrelor's antiplatelet effect was dramatically shortened in the presence of background CYP3A4/5 induction. The offset of antiplatelet effect, defined by platelet reactivity units (PRU), was 10-24hours in the presence of CYP3A4/5 enzyme induction compared to the anticipated 36-48 hours. This was consistent across CYP3A4/5-inducing medications including carbamazepine, phenobarbital, and phenytoin. This study demonstrates rapid return of platelet function after a ticagrelor loading dose in the presence of CYP3A4/5-inducing medications. Monitoring of PRU every 6-12hours with subsequent loading with clopidogrel or prasugrel should be considered. Larger scale studies are warranted to confirm these results.

Neutron diffraction analysis of microstructural evolution and mechanical behavior in an additively manufactured multiphase alloy

Abstract Additive manufacturing (AM) involves an unprecedented thermal history during solidification and post-melt high-temperature exposure, leading to unique microstructural evolution. In this study, we employed neutron-diffraction-based microstructural analysis to better understand the microstructural evolution and mechanical behavior of AM alloys, with a particular focus on multiphase alloys. Samples of Ti−6Al−4V alloy used as a model material were prepared using electron beam powder bed fusion (EB-PBF) under varying building conditions. Time-of-flight neutron diffraction (TOF-ND) measurements were performed using an iMATERIA (BL20), J-PARC, Japan. Using Rietveld texture analysis (RTA), we revealed the textural evolution during hierarchical microstructural development from solidification to solid-state phase transformations in the EB-PBF process. The effects of building conditions on the textures in the as-built states and their evolution during subsequent tensile loading were analyzed.

Effect of longitudinal reinforcement ratio on residual flexural capacity of high-strength reinforced concrete beams exposed to impact loading

In this study, it was aimed to investigate the dynamic impact and post-impact performances of high-strength reinforced concrete (RC) beams, which have different ductility and load-bearing capacities. The dynamic behavior and impact damages of RC beams were compared after exposure to a constant magnitude of impact energy. The applied impact energy was obtained by dropping a mass of 360 kg from a certain height of 3 m. The cross-section dimensions and length of the specimens were selected to carry out the experiments in full-scale. The tested specimens were designed with five different longitudinal reinforcement ratios for demonstrating distinct structural behavior mechanisms that vary from pure flexure to pure shear, representing different ductilities, load-bearing capacities and potential failure characteristics. The post-impact behavior of the impacted RC beams was also assessed by performing quasi-static bending tests on the impact-damaged specimens and the obtained results were compared with the identical undamaged reference RC beams. The results demonstrated that the longitudinal reinforcement ratio (which was intentionally designed for different specimens to exhibit different structural responses from pure shear to pure flexural and different shear-flexure mechanisms) significantly influences the dynamic response and damage intensity of the beams, which, in turn, affect their post-impact static performance. Key structural characteristics, including residual displacement, ductility, energy dissipation, load-carrying capacity, and stiffness, were analyzed. It was found that the mechanical properties of the beams deteriorated markedly after impact exposure. A crucial finding of this research is the notable shift in failure modes from flexural to shear after impact, depending on the damage severity. In RC beams, shear damage remains insignificant under both impact loading and subsequent static loading when the ratio of shear strength to flexural strength (Vr/Mr) exceeds 1.5. Conversely, when this ratio is less than 1.5, the behavior transitions to being shear-critical or shear-dominant. This study presents, for the first time, comprehensive experimental results on the impact-induced damage progression, failure mechanisms, and residual behavior of high-strength RC beams. These insights are vital for understanding the performance of RC structures under impact loads and contribute significantly to the field of structural engineering, particularly in designing impact-resilient structures.

Mitigating skeletal muscle wasting in unloading and augmenting subsequent recovery.

Skeletal muscle wasting is the hallmark pathophysiological adaptation to unloading or disuse that demonstrates the dependency on frequent mechanical stimulation (e.g. muscle activation and subsequent loading) for homeostasis of normally load-bearing muscles. In the absence of mitigation strategies, no mammalian organism is resistant to muscle atrophy driven by unloading. Given the profound impact of unloading-induced muscle wasting on physical capacity, metabolic health and immune function; mitigation strategies during unloading and/or augmentation approaches during recovery have broad healthcare implications in settings of bed-bound hospitalization, cast immobilization and spaceflight. This topical review aims to: (1) provide a succinct, state-of-the-field summary of seminal and recent findings regarding the mechanisms of unloading-induced skeletal muscle wasting; (2) discuss unsuccessful vs. promising mitigation and recovery augmentation strategies; and (3) identify knowledge gaps ripe for future research. We focus on the rapid muscle atrophy driven by relatively short-term mechanical unloading/disuse, which is in many ways mechanistically distinct from both hypermetabolic muscle wasting and denervation-induced muscle atrophy. By restricting this discussion to mechanical unloading during which all components of the nervous system remain intact (e.g. without denervation models), mechanical loading requiring motor and sensory neural circuits in muscle remain viable targets for both mitigation and recovery augmentation. We emphasize findings in humans with comparative discussions of studies in rodents which enable elaboration of key mechanisms. We also discuss what is currently known about the effects of age and sex as biological factors, and both are highlighted as knowledge gaps and novel future directions due to limited research.

Mechanical behaviors and progressive fracture processes of dry basalt after Martian cryogenic freeze-thaw cycles

The steep Martian terrain features numerous notches and alcoves that could potentially be adapted as temporary shelters. By sealing their entrances and modifying the interior space, these alcoves can be transformed into habitable structures. Given their prolonged exposure to Martian temperature fluctuations, it is crucial to understand the mechanical properties of alcove rocks to design appropriate shelter parameters. This study investigates the mechanical behavior of basalt specimens subjected to Martian cryogenic freeze-thaw (F-T) cycles (−143∼35 °C) and subsequent uniaxial cyclic loading tests. The test results indicate that the longitudinal wave velocity, peak stress, and elastic modulus of basalt specimens degrade to varying degrees with an increasing number of F-T cycles. At higher stress levels, the ratio of dissipated energy density to elastic energy density in basalt specimens subjected to different F-T treatments converges to approximately 0.25. During the uniaxial cyclic loading tests, both cumulative acoustic emission (AE) counts and average maximum principal strains of the specimens increase stepwise. For specimens after F-T treatment, the spectral-domain characteristics can be classified into three frequency bands, with the middle and high frequencies predominating. The application of the Gaussian Mixture Model (GMM) clustering algorithm enhances the analysis of AE results, facilitating the identification of tensile and shear cracks. As the number of F-T cycles increases, the percentage of shear cracks in basalt specimens decreases from 76.5% (0 cycle) to 53.5% (7 cycles).

Enzyme-loaded manganese−porphyrin metal−organic nanoframeworks for oxygen-evolving photodynamic therapy of hypoxic cells

Photodynamic therapy (PDT) is attracting great attention for cancer treatments, while its therapeutic efficacy is limited by unsatisfactory photosensitizers and hypoxic tumor microenvironment (TME). To address these problems, we have developed catalase-loaded manganese-porphyrin frameworks (CAT@MnPFs) for catalytically-assisted PDT of cancer cells. CAT@MnPFs were constructed by the assembly of Mn2+ ions and PpIX into MnPFs and the subsequent loading of catalase. Under 650 nm light irradiation, the porphyrin (Protoporphyrin IX) within the structure of CAT@MnPFs can convert oxygen (O2) into singlet oxygen (1O2), showing the photodynamic effect. Importantly, the loaded catalase can decompose hydrogen peroxide (H2O2) into O2 with a huge elevation of O2 level (13.22 mg L−1) in 600 s, thus promoting 1O2 generation via PDT. As a result, CAT@MnPFs combined with 650 nm light can effectively ablate cancer cells due to the catalase-assisted oxygen-evolving PDT, showing a high therapeutic efficacy. Meanwhile, after the incubation with CAT@MnPFs, unobvious damage can be found in normal and red blood cells. Thus, the obtained CAT@MnPFs integrate the advantage of photosensitizers and catalase for oxygen-evolving PDT, which can provide some insight for treating hypoxic cells.

Effect of electromagnetic force installation method on critically reinforced interference sizes and fatigue behavior of CFRP bolted joints

AbstractThe electromagnetic force dynamic installation (DI) method of interference fit fasteners has significant advantages in improving the quality of the assembly interface of composite structure. This study aims to investigate how improving assembly interface quality may help in achieving high‐precision interference‐fit joints in composites. Single‐lap joint specimens were prepared using electromagnetic installation technique, the fatigue life and failure behaviors of the joints under different bolt‐hole clearances were measured and analyzed experimentally. In addition, a three‐dimensional finite element model was developed to predict the radial pre‐compression stresses around the hole and the progressive failure behavior of various typical damage modes in carbon fiber‐reinforced polymer induced by the interference. The results show that the critical interference range for the DI‐composite bolted structure is 1.0%–1.2%. The fatigue life of the best interference (1.0%) and the worst interference (0%, neat fit) have a difference of 36 times in amplitude. The residual stress with uniform distribution and high amplitude reduces the stress concentration of the hole wall and improves the failure evolution of the loaded hole. The contribution of this study provides vital guidance for improving the fatigue performance of CFRP bolted structures using a novel DI method.Highlights I = 1.0% is the critical damage‐enhancing interference size for dynamically installation interference fit bolts with electromagnetic forces. The residual stress amplitude introduced by the interference does not increase uniformly as the interference size increases. Excessive interference significantly reduces the uniformity and magnitude of residual stresses. Under subsequent cyclic loading, the fifth layer near the inlet and outlet of the extruded lower laminate appears to be the critical ply of extrusion deformation, and severe damage is concentrated in the critical ply of deformation. The decrease of stress amplitude and the variation of mean stress are the mechanisms of fatigue life enhancement in interference fit joints under external cyclic loading.

Efficient Tandem Copper-Catalyzed Click Synthesis of Multisugar-Modified Oligonucleotides.

Nucleic acids in the form of siRNA, antisense oligonucleotides or mRNA are currently explored as new promising modalities in the pharmaceutical industry. Particularly, the success of mRNA-vaccines against SARS-CoV-2, along with the successful development of the first sugar-modified siRNA therapeutics has inspired the field. The development of nucleic acid therapeutics requires efficient chemistry to link oligonucleotides to chemical structures that can improve stability, boost cellular uptake, or enable specific targeting. For the siRNA therapeutics currently in use, modification of the 3'-end of the oligonucleotides with triple-N-acetylgalactosamine (GalNAc)3 was shown to be of significance. This modification is currently achieved through cumbersome multistep synthesis and subsequent loading onto the solid support material. Herein, we report the development of a bifunctional click-reactive linker that allows the modification of oligonucleotides in a tandem click reaction with multiple sugars, regardless of the position within the oligonucleotide, with remarkable efficiency and in a one-pot reaction.

Liposome fusion assisted delivery of silica nanoquenchers for rapid detection of exosomal MicroRNAs

Analysis of exosome information in bodily fluids is an important priority in liquid biopsy. Exosomal microRNAs (miRNAs) have been increasingly identified as credible objects due to their high stability and abundance. However, traditional detection techniques for exosomal miRNAs consume considerable time and require abundant professional equipment. Herein, we introduced a novel silica nanoquencher (qSiNP)-based nanoplatform with liposomal shell encapsulation. Liposomes were demonstrated to efficiently deliver qSiNPs into tumor exosomes via membrane fusion pathways. Subsequent loading of qSiNPs with fluorophore-labeled antisense oligonucleotides rapidly resulted in a specific fluorescent signal for “off-on” switchable in situ detection and imaging of targeted exosomal miRNAs without complicated RNA extraction or targeted amplification. With this strategy, the distinction of tumor-related miRNAs from normal exosomes was successfully achieved, which further indicated that our platform has the merits of easy preparation, stable encapsulation, efficient uptake, and an alterable molecular beacon, for improving the diagnostic value of liquid biopsy in various cancer diseases.

Torsion and Combined Torsion-Axial Load Behaviour of Concrete Filled Steel Tube Columns with and without ECC/CFRP Wrap

ABSTRACT Concrete-filled tube columns may experience coupled torsion and axial compression under seismic and wind loading. Fifteen square, rectangular, and circular concrete filled steel/aluminium tube (CFST/CFAT) are tested under pure torsion to understand the behaviour and develop/validate finite element (FE) models. Parametric studies under pure torsion are conducted using FE models to study the effect of geometric (tube cross-section, length, and thickness) and tube/concrete material parameters on torsional strength, stiffness, and tube-concrete composite interaction. FE models are used to study strength, stiffness, and failure modes of CFST columns under combined torsion and axial compression load at various preload levels of axial and torsion. Coupled torsional preloading and subsequent axial load reduce the axial load capacity significantly, while coupled axial preloading and subsequent torsional loading have shown no significant influence on the torsional strength of CFST columns. Implementation of FE models developed for CFST columns with engineered cementitious composite (ECC) and carbon fibre reinforced polymer (CFRP) wraps showed significant enhancement of axial strength and stiffness compared to control (without wrap) even under high torsional preload level. The energy absorption capacity and ductility of the CFRP wrapped CFST column are about 1.38 and 1.1 times higher than its counterpart with ECC wrap of same axial load capacity. Overall, the results suggest that use of both CFRP and ECC wrap is an effective approach to enhance the torsional behaviour and ductility of CFST columns under combined torsion and axial loading conditions. However, high crack resistance and better post-peak ductility of ECC wrapped CFST compared to sudden CFRP rupture failure in CFRP-wrapped counterpart should be taken into consideration for seismic applications.

Influence of repeated surface surcharge loading on tunnel displacement considering the structural characteristics of soft clay

Shanghai soft clay is a typical marine clay with specific structural characteristics. However, the effects of surface surcharge loading on structured soft clay and existing tunnels remain unclear. In this study, the effect of repeated surface surcharge loading on tunnel displacement was numerically investigated, considering the structural characteristics of Shanghai Layer 4 soft clay. An elastoplastic constitutive model (Shanghai model) that describes the mechanical properties and structural characteristics of natural clay was used to simulate the soil response. The results indicate that the first cycle of repeated surface surcharge loading had the greatest effect on the displacement of the tunnel and overlying clay; subsequent loading cycles further increased the displacement. With repeated surface surcharge loading, the displacement of the overlying clay exhibited a significant decreasing trend with increasing depth. The maximum excess pore pressure of the clay exhibited a decreasing trend with increasing loading time. The displacements of the tunnel and overlying clay were greater when the effects of the soil structure were considered. However, the initial degree of the structure had no significant effect on the accumulation of excess pore pressure when the surface surcharge loading did not reach the ultimate bearing capacity of the clay.