This work aims to provide a compact, flexible, lightweight ultra-wideband antenna design with enhanced bandwidth for medical applications. The proposed antenna features fractal geometry and is made by iterating a hexagonal slot within a circular copper construction. The basic radiator’s partial ground plane is defective with a slit at the centre and a down ramp on both sides of the plane. A stub in the feed line improves impedance matching and provides enhanced −10dB bandwidth of 10.6 GHz (1.9 GHz to 12.5 GHz). The antenna is built on a black jeans textile substrate of dielectric constant 1.7 and size of 48 mm × 36 mm × 1.7 mm . The maximum gain of 6.75 dB at the frequency of 2.3 GHz is reported. In the operational band, the developed antenna provides steady radiation properties. Furthermore, the antenna has been verified for use in practical applications by setting up the proposed antenna as a receiver with an NRF24L01 wireless transceiver module and given coverage up to 50 feet in an open environment. The designed prototype is analysed for flexibility with different bending radii. A SAR analysis is also carried out for 1 gram and 10-gram of tissue along with the extensive time domain analysis for wearable UWB applications.