Standard Control System Research Articles

Correlation between subretinal tissue plasminogen activator and air injection rates with pressure in a retina mimicking model

By investigating the correlation between the injection rate and pressure of subretinal tissue plasminogen activator (tPA) and air using a standard Viscous Fluid Control (VFC) system with a 38-gauge cannula, we aimed to establish guidelines for stable injections. We fabricated a retina mimicking model (RMM) with 0.25% agarose solution and an aluminum plate, and substituted submacular hemorrhage (SMH) and tPA with blood-mimicking fluid (BMF) and balanced salt solution (BSS), respectively. The diameter of the pre-bleb mimicking SMH in RMM was 1.30 ± 0.16 cm, increasing to 1.98 ± 0.24 cm and 1.83 ± 0.22 cm after bleb propagation with BSS and air, respectively. BSS injection rates were 2.86 ± 0.04 µl/sec, 6.74 ± 0.48 µl/sec and 8.55 ± 0.16 µl/sec at 8, 12, and 16 psi, respectively. Air injection rates were 37.98 ± 3.11 µl/sec, 79.01 ± 5.13 µl/sec and 156.06 ± 13.72 µl/sec at 2, 3 and 4 psi, respectively. By experimenting with different pressures in the RMM, we found 12 psi to be the minimum for proper BSS injection and 2 psi for air. These findings provide crucial parameters for safer surgery to prevent irreversible damage.

Система автономного управления дорожно-строительной машиной

The increasing requirements for the accuracy of construction work lead to the need to create modern control systems that will eliminate the human operator from the process of controlling road construction machines, increase the energy efficiency and productivity of these machines, as well as the quality of the finished construction object. The use of unmanned control systems has become an absolute technological break-through. Improving the accuracy of work with the help of unmanned control systems is an urgent and complex area of research. This is due to the need to improve algorithms and improve sensors to more accurately de-termine the coordinates of the machine and make decisions. Only by possessing high accuracy, modern unmanned vehicles are able to minimize errors in construction work and associated safety risks. To do this, it is necessary to provide the ability to recognize and analyze various factors, such as moving objects, weather conditions, terrain, etc. The article presents the results of a functional analysis of a number of road construction machines, defines the range of tasks that a modern unmanned control system should solve, describes a possible implementation option for such a system, and shows the differences in flowcharts of working processes of construction machines both without automatic control systems and equipped with standard and developed automatic control systems.

Role of ultrasensitivity in biomolecular circuitry for achieving homeostasis

Living systems have developed control mechanisms for achieving homeostasis. Here, we propose a plausible biological feedback architecture that exploits ultrasensitivity and shows adaptive responses without requiring error detection mechanism (i.e., by measuring an external reference signal and deviation from this). While standard engineering control systems are usually based on error measurements, this is not the case for biological systems. We find that a two-state negative feedback control system, without explicit error measurements, is able to track a reference signal that is implicitly determined by the tunable threshold and slope characterizing the sigmoidal ultrasensitive relationship implemented by the control system. We design different ultrasensitive control functions (ultrasensitive up- or down-regulation, or both) and, by performing sensitivity analysis, show that increasing the sensitivity level of the control allows achieving robust adaptive responses to the effects of parameter variations and step disturbances. Finally, we show that the devised control system architecture without error detection is implemented within the yeast osmoregulatory response network and allows achieving adaptive responses to osmotic stress, by exploiting the ubiquitous ultrasensitive features of the involved biomolecular circuitry.

Reflections on good manufacturing practice and quality control system of personalized traditional Chinese medicine preparations

Personalized traditional Chinese medicine(TCM) preparations have entered a stage of rapid development. The key to the healthy development of this industry is to establish a sound manufacturing standard and quality control system. This paper analyzed the characteristics of personalized TCM preparations and drew reference from the quality management standards in the production of commissioned decoctions and oral pastes, on the basis of which the production quality management scheme and cautions for the safe production of personalized TCM preparations was put forward with consideration to various problems that may exist and occur in the production of such preparations. It provided references for formulating the production standards and quality management system of personalized TCM preparations. The production standards and quality control system should develop with the times. In the future, modern technologies such as big data and artificial intelligence should be employed to achieve the automated and intelligent production and establish a sound quality traceability system, online control strategy, and safety management mode of personalized TCM preparations, which will ensure the healthy development of this industry under requirement of good manufacturing practice(GMP).

The advanced motion control system in HEPS beamline

In synchrotron radiation facilities such as the High Energy Photon Source (HEPS), numerous motorized actuators are equipped on the optics devices of HEPS beamline to manipulate the orientation of crystals and mirrors, thereby altering the position and characteristics of X-rays. The motion control system (MCS) plays an important role in the optics devices of HEPS beamlines, such as monochromator, K-B mirror and sample plants. In order to acquire the specify properties of X-ray and satisfy the complex experimental requirements, MCS must have the ability to handle the complicated control demands. Therefore, HEPS has developed a standardized motion control system for synchrotron radiation applications, which is a distributed system based on EtherCAT fieldbus. The hardware of this system consists of the control unit and driver unit, which has the flexibility to suit for different applications. The software of MCS is designed under the Experimental Physics and Industrial Control System (EPICS), which is very popular in synchrotron radiation facilities all over the world. In this paper, the performance tests of IOC software were demonstrated, and a few flyscan applications were given, which include spiral scan, raster scan and position event trigger, to demonstrate the feasibility and effectiveness of this system.

2016–2017年小浪底栓皮栎人工林碳水通量观测数据集

The concern about global change has brought more attention to the role of plantations in the regional carbon and water cycle recently. Quercus variabilis is one of the most widely distributed natural tree species in China. The southern foot of Taihang Mountain is one of the key areas of forestry engineering in China. The study on the observation of water and carbon fluxes in a Quercus variabilis plantation in this area is of great significance to the development of forestry ecological engineering and the evaluation of plantation carbon sink function in China. Henan Xiaolangdi Earth Critical Zone National Research Station on the Middle Yellow River (i.e. XLD) has carried out long-term observation of and research on the carbon and water fluxes in a Quercus variabilis plantation using the eddy covariance technique since 2005. This dataset contains carbon and water flux observations and meteorological data collected from XLD from 2016 to 2017, which have been processed in accordance with the standard quality control system of ChinaFLUX. It covers the data of gross ecosystem primary productivity, ecosystem respiration, net ecosystem carbon exchange, latent heat flux, sensible heat flux and other related meteorological factors, such as air temperature, air relative humidity, vapor pressure, wind speed, wind direction, radiation, soil temperature, soil moisture, precipitation, etc. The dataset is composed of the data collected at the scales of half-hourly, daily, monthly, and yearly intervals. This dataset can provide data support for the management of plantation ecosystems and the assessment of regional carbon budgets. Moreover, it plays a crucial role in promoting data sharing and standardization management of field stations in China.

Implementation of Control Standardization Based on HCM5000G DC Control and Protection Platform

This paper introduces the whole construction of the control standardization simulation system based on the HCM5000G DC control and protection platform, which can meet the requirements of engineering design and various control performance indexes by adopting the standardization design of the self-control and localization platform. In this paper, the construction principle of the standardized control system and the optimization strategy of the control structure are discussed in detail, and the engineering simulation model is realized by using the real-time digital simulation system with the layered and distributed standardized interface design, which provides an important reference for the future large-scale application of the control and protection of DC Engineering.

Implementation of an Algorithm for Extracting Information about Structural Elements of Text Documents in ODT Format

The dependence of the XML markup of a digital document in the ODT format on the tool that was used to create it is considered. Not only specialized tools are used in comparison, but also those that do not directly work with the ODT format to identify the most vulnerable spots. The features of extracting data from the structural elements of the document, such as tables, lists and images, are also described. The implementation of an algorithm for obtaining style attributes used to create a system for automated normative control of digital documents is proposed and described. It is revealed that the non-strict standard of the ODT format led to the dependence of XML markup on the text editor that was used to create the document. And, as a result, to a limited number of tags that can be relied upon when developing document parsing algorithms. However, the task is feasible, as demonstrated in the article. Likewise, the default values, the description of the algorithm for bypassing the document in blocks and structural elements form the basis for preparing data for the subsequent creation of a classifier and automation of the process of normative control. Thus, the algorithm proposed in the article and the analysis of XML markup performed are effective tools for solving the problem of creating an automated document standard control system, and the algorithm has the potential for further improvement.

Research Progress on Mesenchymal Stem Cells for the Treatment of Diabetes and Its Complications.

Diabetes mellitus (DM) is a chronic disease that threatens human health. Although many drugs are available to treat DM, various complications caused by DM are unavoidable. As an emerging treatment for DM, mesenchymal stem cells (MSCs) have shown many advantages and are gradually gaining public attention. This review summarizes the clinical studies on the use of MSCs to treat DM and the potential mechanisms of complications such as pancreatic dysfunction, cardiovascular lesions, renal lesions, neurological lesions, and trauma repair. This review focuses on the research progress on MSC-mediated secretion of cytokines, improvements in the microenvironment, repair of tissue morphology, and related signaling pathways. At present, the sample sizes in clinical studies of MSCs in treating DM are small, and there is a lack of standardized quality control systems in the preparation, transportation, and infusion methods, so we need to conduct more in-depth studies. In conclusion, MSCs have shown superior potential for use in the treatment of DM and its complications and will hopefully become a novel therapeutic approach in the future.

Wind turbine structural control using H-infinity methods

Wind turbines are complex dynamic structures, exposed to random wind input exciting several structural modes. In recent years, the wind turbines have evolved to large-scale machines, with rotor diameter and tower height attaining unforeseen dimensions compared to initial commercial wind turbines. In this context, the structure design has become more flexible and susceptible to dynamic actions, rising the need for the development of active structural control methodologies. On the other hand, the wind turbine dispose of standard control systems, dedicated to operational control. The use of these control systems to mitigate wind turbine loads is feasible due to the dynamic couplings within the structure, and could provide a significant comparative advantage to the new wind turbine structures. In order to provide structural control from conventional wind turbine control, it is necessary to deploy a suitable modeling and the use of advanced control methods. In this paper, the use of H∞ control design is combined with wind turbine dynamics equations to develop an active structural control to reduce wind turbine tower loading. Dynamic simulations under steady and turbulent conditions demonstrate the effectiveness of the proposed approach.

DETERMINATION OF THE TEMPERATURE FIELD DISTRIBUTION IN THE WINDING RODS OF THE STATOR OF TURBOGENERATORS OF TYPE TVV FOR PURPOSES OF CONTROL AND DIAGNOSTICS

Turbogenerators were and remain the most unreliable element at nuclear power plants in Ukraine. The most dangerous disturbances in the operation of turbogenerators of the TVV type is complete or partial blockage of the hollow conductors of the stator winding. The systems of operational control and technical diagnostics today, in a number of cases, cannot cope with the identification of these phenomena. The complex application of adequate mathematical models, indications of the standard thermal control system and new diagnostic features give the opportunity with sufficient accuracy for practical purposes to detect blockages in the hollow conductors of the stator windings of these turbogenerators. The aim of the work is to develop a program for calculating the three-dimensional temperature field in the rods of the stator winding of a turbogenerator of the TVV-1000-2U3 type, taking into account the temperature field of the stator core, to carry out a test calculation and to compare the experimental and to calculated data. The problem is solved with the help of the finite difference method using the integro-interpolation method.

Methodology of Analysis of Thermal Vision Parameters of NPP Standby Diesel Together with Standard Instrument Readings

Analytical studies of the results of thermal imaging control using IAS TIK together with the corresponding values of the temperature control results obtained in the standard DGS condition monitoring system were carried out within the framework of R&D for the development of an integrated automated system for thermal imaging control (IAS TIK). Approbation of IAS TIK in NPP conditions was carried out by thermography of standby diesel generator sets of NPP type 12zv40/48+S2445-12. At the same time, the parameters of the diesel engine and the generator were measured using the standard control system. The methodology is proposed that provides an analysis of the uniformity of the operation of diesel cylinders, the condition of the crankshaft bearings, the condition and quality of the generated electricity of the generator, as well as the analysis of the operation of lubrication and cooling systems. The practical application of the technique demonstrates the correspondence between the temperatures measured by the standard system and the IAS TIK. A joint analysis of the results obtained by the standard and developed systems provides an increase in the depth of the diagnostic examination and confirms the information content of the thermographic parameters and the quality of the measurement channels of the standard systems. The parameter values obtained from the analysis of the indicators of the standard control system, recorded at a steady power value, will be used in subsequent diagnostics to establish trends in these parameters

Design of a new robust controller for voltage regulation of DC link in wind‐farm‐side converter integrated with a hybrid AC and DC large‐scale power system

Design of a new robust controller for voltage regulation of DC link in wind‐farm‐side converter integrated with a hybrid AC and DC large‐scale power system

SG-APSIC1110: Project quality development of zero stock

Objectives: Many medical devices and equipment have been reserved in hospital wards and outpatient departments. Among these items, >80% are not often used but are being reserved for emergency situations. We aimed to reduce the number of unnecessarily reserved medical devices and to reduce the cost of unnecessary resterilization of devices and equipment. Methods: The central sterile supply department (CSSD), in coordination with other 13 wards within the Thammasat University Hospital, established a standard action plan for improving the efficiency of medical supply stocking and storage. Medical equipment and/or devices were returned to the CSSD, which acted as the center of management and distribution. The CSSD also tracked and solved problems that occurred and reevaluated practice guidelines. User satisfaction was evaluated and statistic data were collected and analyzed. Results: Wards no longer reserve medical equipment. Thus, no repeated sterilization was needed for unused medical equipment from the participated 13 wards, and sufficient medical equipment was available for various wards when needed. This project helped reduce the cost of purchasing medical equipment, especially for a newly opened ward. The storage of all medical equipment and devices complied with the practice guidelines because the CSSD storage room had a standard temperature and humidity control system. Conclusions: In this project, the CSSD cooperated with the 13 participating wards. As the result of centralizing the supplies, the CSSD has sufficient medical equipment and devices for all other wards, including a newly opened ward. The hospital benefitted from reduced costs of purchasing new medical equipment for a newly opened ward as well as the cost savings of eliminating unnecessary resterilization of unused devices and equipment.

Ether-IoT: A Realtime Lightweight and Scalable Blockchain-Enabled Cache Algorithm for IoT Access Control

Several unique characteristics of Internet of Things (IoT) devices, such as distributed deployment and limited storage, make it challenging for standard centralized access control systems to enable access control in today’s large-scale IoT ecosystem. To solve these challenges, this study presents an IoT access control system called Ether-IoT based on the Ethereum Blockchain (BC) infrastructure with Attribute-Based Access Control (ABAC). Access Contract (AC), Cache Contract (CC), Device Contract (DC), and Policy Contract (PC) are the four central smart contracts (SCs) that are included in the proposed system. CC offers a way to save user characteristics in a local cache system to avoid delays during transactions between BC and IoT devices. AC is the fundamental program users typically need to run to build an access control technique. DC offers a means for storing the resource data created by devices and a method for querying that data. PC offers administrative settings to handle ABAC policies on users’ behalf. Ether-IoT, combined with ABAC and the BC, enables IoT access control management that is decentralized, fine-grained and dynamically scalable. This research gives a real-world case study to illustrate the suggested framework’s implementation. In the end, a simulation experiment is performed to evaluate the system’s performance. To ensure data integrity in dispersed systems, the results show that Ether-IoT can sustain high throughput in contexts with a large number of requests.

Neural network pressure observerfor a turbomechanism electromechanical system powered by a wind generator

Ecological and economic production of electrical energy through the use ofalternative energy sources is an urgent direction due to the trend of increasing prices of energy carriers used in the electrical energy production and as a result of significant damage of the energy system of Ukraine in consequence of the war on the country territory.It is worth noting that in some areas it is possible to use only autonomous power generation systems, since the laying of electrical networks in these districts is impractical and unprofitable. Usually, the mentioned systems are basedon a combination of a wind or hydro turbine -drive motor, and an electric generator. Such systems are characterized by high resource, reliability, low cost,and complexity of maintenance. Sometimes people's lives and the possibility of communication withthe outside world depend on the operation of an autonomous electric power generation system, which is especially important in the conditions of martial law. At the same time, the lack of stabilization of the hydraulic networkpressureof the water supply system can lead to the household conditions aggravation, the emergency situations occurrence, and the technological process disruption.In view of the mentioned factors, there is a need to measure the pressure of the hydraulic network, which is possible byusing technological coordinatesobserversbuilt on the basis of the artificial networks theory. In the paper a modern turbomechanism electromechanical control systempowered by an alternative electrical energy source under the conditions of pressure stabilization of thehydraulic network when using atechnological coordinatesobserver, namely a pressure estimator, is proposed. A mathematical description of the main elements of the investigatedsystem is given. A hydraulic network pressure observerbased onthe artificial neural networks theory isbuilt and studied. Features of design and training of technological coordinate estimators based on neural networks with feedback are described. The operation of the sensorless system during thepressure stabilization at a given level when the resistance of the hydraulic network changes within the typical daily cycle of water consumption is considered on a specific example. The results and analysis of the investigationof the developed observerin standard and sensorless control systems are shown.

Моделирование влияния нагрузки судовых дизелей на работу системы охлаждения

The article provides analysis of the load effect of the marine internal combustion engines (ICE) on the tem-perature parameters of the water cooling system of ICEs equipped with L32-40 Vis diesel engines. In ICE cooling systems the drive motors of the pumps supplying the cooling water operate at a constant speed and provide a constant water supply. The thermal state of a marine diesel ICE is regulated by valves according to deviation of the actual temperature values of cooling water from the preset values. By closing or opening the water lines the valves change the proportion of cooling water flows of the external and internal circuits fed to the heat exchangers. There is implemented the principle of regulating the deviation of the main coordinate - the temperature of the cooling water. The influence of other factors on the operation of the system is taken into account with a delay. Modeling the operation of the high-temperature circuit of the cooling system of the main ship engine of the ferry was carried out using the simulator 
 of the engine room TRANSAS TechSim 5000. There have been obtained graphical results of changing the cooling circuit water temperature with increased and decreased loads on diesel engines by changing the set speed with different initial and final values at a constant water temperature in the external cooling circuit. The graphs helped obtain numerical and qualitative indicators of transient processes (duration, oscillation, overshoot, final temperature values, etc.) for the different initial conditions - ranges of diesel load changes. The resulting graphical dependences are analyzed, conclusions about the modes of working out the disturbing influences by the cooling system, the parameters 
 of transient processes and the features of the operation of the standard control system and the cooling system circuit 
 of the main marine diesel engine in terms of ensuring optimal performance of the system are drawn. It has been inferred that the standard control system under some initial conditions does not provide the optimal parameters of transient processes.

Stability of virtual reality haptic feedback incorporating fuzzy-passivity control

This study investigated the stability of virtual reality (VR) haptic feedback from the perspective of energy. A fuzzy controller was designed on the basis of passivity theory to mitigate the shock and divergence in a virtual component caused by the negative damping coefficient and the high spring coefficient. Compared with a standard passivity controller, a fuzzy-passivity controller is more effective in shortening the time required to stabilize a system with high initial energy and devices that consume energy slowly. First, MATLAB/Simulink was employed for stability simulation and analysis. The fuzzy-passivity controller provided more favorable stability convergence than did the standard passivity controller. The simulation results align with expectations. Second, the completed VR system was applied as an experiment platform for verifying the feasibility of the fuzzy-passivity controller. To achieve one degree of freedom in the experiments, a robotic arm was exclusively designed to replace manual force. Finally, compared with standard passivity control systems, the results indicated that the fuzzy-passivity controller enables improved control over the stability of VR haptic feedback.

Явище гістерезису при тепловіддачі кипінням у двофазних контурах теплоперенесення

Systems for ensuring the thermal regime of ground and space applications with a capacity of more than 6 kW are rationally built on the basis of heat transfer circuits with a two-phase coolant. In such circuits, heat is transferred from the devices to the coolant in the heat sink (thermoplate) by heat transfer by boiling. When the device is switched on and heated up, there is a transition from single-phase convection to developed boiling in the evaporator channel of the Heat sink, which is sometimes accompanied by significant overheating of the device and a temperature drop. When the device is turned off, the temperature decreases smoothly, without a drop. This undesirable phenomenon, called "thermal load hysteresis", or "Hysteresis Phenomena at the Onset of Nucleate boiling" can affect the reliability of the device, and is the subject of study in this article. The problem of hysteresis has been studied by many authors at the local level both during boiling in a large volume and during the flow of coolant in the channels. It is associated with the need for some overheating of the wall to start boiling, the origin of vaporization centers. This article reviews the studies on the problem of hysteresis and describes a task for the experimental study of the phenomenon of hysteresis in the evaporator channel of a heat sink during the transition from single-phase convection to boiling. Tasks: it is necessary to consider the factors affecting hysteresis and to develop and test a methodology for conducting the experiment on the stand of simulation of heat transfer circuits with a two-phase coolant at the integral level. According to the results of the review, it was found that hysteresis is affected by various factors such as the properties of the coolant, surface roughness, flow parameters, etc. Usually, the study of hysteresis is conducted out at the local level, but engineering practice is interested in the phenomenon at the integral level, and what is the probability and magnitude of overheating of the device when it is turned on. However, if hysteresis exists at the local level, it is not obvious that hysteresis will appear at the device level. The authors obtained a "boiling curve" of ammonia on an experimental heat sink with a characteristic temperature drop of the device and showed that the phenomenon of hysteresis exists at the integral level. Conclusions. Considering the probabilistic nature of the phenomenon, many factors affecting the hysteresis, including the design features of the thermoplate, the authors propose to perform further studies using the "integral" methodology on standard coolants, with parameters close to the operating conditions of standard thermal control systems.

A novel test technology for a standardized stability control system and its test platform

The stability control system is the second defense line of the power system, and the test before applying the stability control system is a key link to ensure the performance of the system. Since the configuration and strategy of the standardized stability control system are related through the setting of fixed value items, it is necessary to comprehensively consider the coupling between different application scenarios, different operation modes, and different stability control strategies to verify the functions of each device. Starting from the design concept and function of the standardized stability control system, this paper introduces the test scheme of the standardized stability control system from three aspects: monomer test, static test, and strategy verification test. Besides, the test platform of the stability control system based on RTDS is built, which lays the foundation for the stability control test and ensures that the standardized stability control system meets the requirements of regulations and specifications.