Pile-up effects due to the overlap of signals within the system dead-time (τ) influence the counting capability of radiation detection devices, necessitating the use of correction algorithms to compensate for the count-losses at high radiation rates. Count-rate linearity is especially critical for clinical applications like X-ray imaging or beam monitoring in particle therapy. In particular, in proton therapy the number of delivered particles must be measured online during the treatment session with a maximum error of 1 % up to an average input beam flux of about 1010cm−2s−1. For a segmented detector used to identify and count the single beam particles, assuming a channel area of 1 mm2 and a dead-time τ=2ns, a maximum counting inefficiency of 1 % is required up to τ.fin=0.2 for each detector channel, where fin represents the input rate. Moreover, the beam is often delivered in bunches with higher instantaneous particle rates, and the saturation model of the detector and electronic chain could not be easily determined. Similar considerations are applicable for pixelated detectors used for photon counting.Two methods are proposed to mitigate counting inefficiencies with radiation sources of variable time-structures. Both methods are based on the collection of logic signals provided by two independent detector channels exposed to the same radiation field after discriminating the detector analog outputs with a fixed threshold, assuming that the duration of the discriminator output signal corresponds to the system dead-time. The correction algorithms employ the measurements of the time durations, the number of signals from the two channels and of their AND/OR combinations. The methods provide count-loss corrections without the need to know the dead-time model.The performances of the proposed algorithms are evaluated by using simulations of ideal boxcar signals of fixed duration τ, distributed randomly in time to emulate the dead-time behavior of the system. Both methods provide an effective count-loss correction with a maximum deviation of 1% for different input rates up to τ.fin=1, assuming a uniform random time distribution of input events for both paralyzable and non-paralyzable systems. The simulations of pulsed radiation fluxes provide the same results as a function of the instantaneous input rates.These results are similar to those obtainable by the standard live-time correction algorithm. However, the latter algorithm can only be applied to continuous particle fluxes, while the proposed algorithms work also for pulsed beams, without any hypothesis on the bunch duration or frequency. The robustness of the algorithms with respect to the resolution of the time measurement is studied and the potential limitations in more realistic systems are discussed.The algorithms can be easily implemented in standard logical circuits with multiple input signals provided by segmented detectors. Even if the methods are intended for real-time correction in beam particle counting, they could be applied in a wider range of applications of radiation measurements.
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