Prior research has provoked the hypothesis that functional loss or impairment of neurophysiological mechanisms underlying surround (or Lateral) Inhibition may mediate the induction of dysregulated pain processing and in turn chronic pain syndromes.1, 2 Though Surround Inhibition is a well-characterized mechanism in the published literature, uncovering how to design Spinal Cord Stimulation (SCS) therapy to engage with surround inhibition previously remained unstudied. Discovery of novel Fast Acting Sub Perception Therapy (FAST) demonstrated attainment of robust and rapid (seconds to minutes) induction of analgesia.3 Further, recently reported real-world data demonstrated profound pain relief with the use of FAST (alone or in combination with other modalities) following implant.4 Here, we present outcomes of a prospective, multicenter study designed to evaluate FAST in the treatment of chronic pain.