Sparse-view Computed Tomography Research Articles

Reconstruction of Sparse-View X-ray Computed Tomography Based on Adaptive Total Variation Minimization.

Sparse-view reconstruction has garnered significant interest in X-ray computed tomography (CT) imaging owing to its ability to lower radiation doses and enhance detection efficiency. Among current methods for sparse-view CT reconstruction, an algorithm utilizing iterative reconstruction based on full variational regularization demonstrates good performance. The optimized direction and number of computations for the gradient operator of the regularization term play a crucial role in determining not only the reconstructed image quality but also the convergence speed of the iteration process. The conventional TV approach solely accounts for the vertical and horizontal directions of the two-dimensional plane in the gradient direction. When projection data decrease, the edges of the reconstructed image become blurred. Exploring too many gradient directions for TV terms often comes at the expense of more computational costs. To enhance the balance of computational cost and reconstruction quality, this study suggests a novel TV computation model that is founded on a four-direction gradient operator. In addition, selecting appropriate iteration parameters significantly impacts the quality of the reconstructed image. We propose a nonparametric control method utilizing the improved TV approach as a solution to the tedious manual parameter optimization issue. The relaxation parameters of projection onto convex sets (POCS) are determined according to the scanning number and numerical proportion of the projection data; according to the image error before and after iterations, the gradient descent step of the TV item is adaptively adjusted. Compared with several representative iterative reconstruction algorithms, the experimental results show that the algorithm can effectively preserve edges and suppress noise in sparse-view CT reconstruction.

Two-and-a-half order score-based model for solving 3D ill-posed inverse problems

Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) are crucial technologies in the field of medical imaging. Score-based models demonstrated effectiveness in addressing different inverse problems encountered in the field of CT and MRI, such as sparse-view CT and fast MRI reconstruction. However, these models face challenges in achieving accurate three dimensional (3D) volumetric reconstruction. The existing score-based models predominantly concentrate on reconstructing two-dimensional (2D) data distributions, resulting in inconsistencies between adjacent slices in the reconstructed 3D volumetric images. To overcome this limitation, we propose a novel two-and-a-half order score-based model (TOSM). During the training phase, our TOSM learns data distributions in 2D space, simplifying the training process compared to working directly on 3D volumes. However, during the reconstruction phase, the TOSM utilizes complementary scores along three directions (sagittal, coronal, and transaxial) to achieve a more precise reconstruction. The development of TOSM is built on robust theoretical principles, ensuring its reliability and efficacy. Through extensive experimentation on large-scale sparse-view CT and fast MRI datasets, our method achieved state-of-the-art (SOTA) results in solving 3D ill-posed inverse problems, averaging a 1.56 dB peak signal-to-noise ratio (PSNR) improvement over existing sparse-view CT reconstruction methods across 29 views and 0.87 dB PSNR improvement over existing fast MRI reconstruction methods with × 2 acceleration. In summary, TOSM significantly addresses the issue of inconsistency in 3D ill-posed problems by modeling the distribution of 3D data rather than 2D distribution which has achieved remarkable results in both CT and MRI reconstruction tasks.

Sparse-View Computed Tomography Reconstruction Based on a Novel Improved Prior Image Constrained Compressed Sensing Algorithm

The problem of sparse-view computed tomography (SVCT) reconstruction has become a popular research issue because of its significant capacity for radiation dose reduction. However, the reconstructed images often contain serious artifacts and noise from under-sampled projection data. Although the good results achieved by the prior image constrained compressed sensing (PICCS) method, there may be some unsatisfactory results in the reconstructed images because of the image gradient L1-norm used in the original PICCS model, which leads to the image suffering from step artifacts and over-smoothing of the edge as a result. To address the above-mentioned problem, this paper proposes a novel improved PICCS algorithm (NPICCS) for SVCT reconstruction. The proposed algorithm utilizes the advantages of PICCS, which could recover more details. Moreover, the algorithm introduces the L0-norm of image gradient regularization into the framework, which overcomes the disadvantage of conventional PICCS, and enhances the capability to retain edge and fine image detail. The split Bregman method has been used to resolve the proposed mathematical model. To verify the effectiveness of the proposed method, a large number of experiments with different angles are conducted. Final experimental results show that the proposed algorithm has advantages in edge preservation, noise suppression, and image detail recovery.

A cascade-based dual-domain data correction network for sparse view CT image reconstruction

Computed tomography (CT) provides non-invasive anatomical structures of the human body and is also widely used for clinical diagnosis, but excessive ionizing radiation in X-rays can cause harm to the human body. Therefore, the researchers obtained sparse sinograms reconstructed sparse view CT images (SVCT) by reducing the amount of X-ray projection, thereby reducing the radiological effects caused by radiation. This paper proposes a cascade-based dual-domain data correction network (CDDCN), which can effectively combine the complementary information contained in the sinogram domain and the image domain to reconstruct high-quality CT images from sparse view sinograms. Specifically, several encoder-decoder subnets are cascaded in the sinogram domain to reconstruct artifact-free and noise-free CT images. In the encoder-decoder subnets, spatial-channel domain learning is designed to achieve efficient feature fusion through a group merging structure, providing continuous and elaborate pixel-level features and improving feature extraction efficiency. At the same time, to ensure that the original sinogram data collected can be retained, a sinogram data consistency layer is proposed to ensure the fidelity of the sinogram data. To further maintain the consistency between the reconstructed image and the reference image, a multi-level composite loss function is designed for regularization to compensate for excessive smoothing and distortion of the image caused by pixel loss and preserve image details and texture. Quantitative and qualitative analysis shows that CDDCN achieves competitive results in artifact removal, edge preservation, detail restoration, and visual improvement for sparsely sampled data under different views.

Template-based CT reconstruction with optimal transport and total generalized variation

x-ray computed tomography (CT) has been widely used in clinical diagnosis as a modality of medical imaging. To decrease the radiation dose patients suffering from, sparse-view CT has gained much attention in medical imaging field. In this paper, we propose to design a variational model based on dynamic optimal transportation and total generalized variation for CT reconstruction. This is a joint task involving inverse problem and template registration. The final state image of the optimal transport problem is unknown and needs to be reconstructed through CT inversion, while the given initial state can be regarded as a template to provide some structural information for the final one. Moreover, the existence and stability of minimizers to our proposed model are shown in continuous space. In discretization with the continuity equation, we utilize the well-known staggered grid in fluid mechanics and develop a first-order algorithm based on primal-dual method for numerically solving the proposed model. Finally, numerical experiments for sparse-view CT reconstruction are exhibited to show the performance of our proposed model in recovering images with high quality and structure preservation.

Sparsier2Sparse: Self-supervised convolutional neural network-based streak artifacts reduction in sparse-view CT images.

Sparse-view computed tomography (CT) has attracted a lot of attention for reducing both scanning time and radiation dose. However, sparsely-sampled projection data generate severe streak artifacts in the reconstructed images. In recent decades, many sparse-view CT reconstruction techniques based on fully-supervised learning have been proposed and have shown promising results. However, it is not feasible to acquire pairs of full-view and sparse-view CT images in real clinical practice. In this study, we propose a novel self-supervised convolutional neural network (CNN) method to reduce streak artifacts in sparse-view CTimages. We generate the training dataset using only sparse-view CT data and train CNN based on self-supervised learning. Since the streak artifacts can be estimated using prior images under the same CT geometry system, we acquire prior images by iteratively applying the trained network to given sparse-view CT images. We then subtract the estimated steak artifacts from given sparse-view CT images to produce the finalresults. We validated the imaging performance of the proposed method using extended cardiac-torso (XCAT) and the 2016 AAPM Low-Dose CT Grand Challenge dataset from Mayo Clinic. From the results of visual inspection and modulation transfer function (MTF), the proposed method preserved the anatomical structures effectively and showed higher image resolution compared to the various streak artifacts reduction methods for all projection views. We propose a new framework for streak artifacts reduction when only the sparse-view CT data are given. Although we do not use any information of full-view CT data for CNN training, the proposed method achieved the highest performance in preserving fine details. By overcoming the limitation of dataset requirements on fully-supervised-based methods, we expect that our framework can be utilized in the medical imagingfield.

MDST: multi-domain sparse-view CT reconstruction based on convolution and swin transformer

Objective.Sparse-view computed tomography (SVCT), which can reduce the radiation doses administered to patients and hasten data acquisition, has become an area of particular interest to researchers. Most existing deep learning-based image reconstruction methods are based on convolutional neural networks (CNNs). Due to the locality of convolution and continuous sampling operations, existing approaches cannot fully model global context feature dependencies, which makes the CNN-based approaches less efficient in modeling the computed tomography (CT) images with various structural information. Approach. To overcome the above challenges, this paper develops a novel multi-domain optimization network based on convolution and swin transformer (MDST). MDST uses swin transformer block as the main building block in both projection (residual) domain and image (residual) domain sub-networks, which models global and local features of the projections and reconstructed images. MDST consists of two modules for initial reconstruction and residual-assisted reconstruction, respectively. The sparse sinogram is first expanded in the initial reconstruction module with a projection domain sub-network. Then, the sparse-view artifacts are effectively suppressed by an image domain sub-network. Finally, the residual assisted reconstruction module to correct the inconsistency of the initial reconstruction, further preserving image details. Main results. Extensive experiments on CT lymph node datasets and real walnut datasets show that MDST can effectively alleviate the loss of fine details caused by information attenuation and improve the reconstruction quality of medical images. Significance. MDST network is robust and can effectively reconstruct images with different noise level projections. Different from the current prevalent CNN-based networks, MDST uses transformer as the main backbone, which proves the potential of transformer in SVCT reconstruction.

Adaptive-weighted high order TV algorithm for sparse-view CT reconstruction.

With the development of low-dose computed tomography (CT), incomplete data reconstruction has been widely concerned. The total variation (TV) minimization algorithm can accurately reconstruct images from sparse or noisy data. However, the traditional TV algorithm ignores the direction of structures in images, leading to the loss of edge information and block artifacts when the object is not piecewise constant. Since the anisotropic information can facilitate preserving the edge and detail information in images, we aim to improve the TV algorithm in terms of reconstruction accuracy via this approach. In this paper, we propose an adaptive-weighted high order total variation (awHOTV) algorithm. We construct the second order TV-norm using the second order gradient, adapt the anisotropic edge property between neighboring image pixels, adjust the local image-intensity gradient to keep edge information, and design the corresponding Chambolle-Pock (CP) solving algorithm. Implementing the proposed algorithm, comprehensive studies are conducted in the ideal projection data experiment where the Structural similarity (SSIM), Root Mean Square Error (RMSE), Contrast to noise ratio (CNR), and modulation transform function (MTF) curves are utilized to evaluate the quality of reconstructed images in statism, structure, spatial resolution, and contrast, respectively. In the noisy data experiment, we further use the noise power spectrum (NPS) curve to evaluate the reconstructed images and compare it with other three algorithms. We use the 2D slice in the XCAT phantom, 2D slice in TCIA Challenge data and FORBILD phantom as simulation phantoms and use real bird data for real verification. The results show that, compared with the traditional TV and FBP algorithms, the awHOTV has better performance in terms of RMSE, SSIM, and Pearson correlation coefficient (PCC) under the projected data with different sparsity. In addition, the awHOTV algorithm is robust against the noise of different intensities. The proposed awHOTV method can reconstruct the images with high accuracy under sparse or noisy data. The awHOTV solves the strip artifacts caused by sparse data in the FBP method. Compared with the TV method, the awHOTV can effectively suppress block artifacts and has good detail protectionability.

An attention-based deep convolutional neural network for ultra-sparse-view CT reconstruction

X-ray Computed Tomography (CT) techniques play a vitally important role in clinical diagnosis, but radioactivity exposure can also induce the risk of cancer for patients. Sparse-view CT reduces the impact of radioactivity on the human body through sparsely sampled projections. However, images reconstructed from sparse-view sinograms often suffer from serious streaking artifacts. To overcome this issue, we propose an end-to-end attention-based mechanism deep network for image correction in this paper. Firstly, the process is to reconstruct the sparse projection by the filtered back-projection algorithm. Next, the reconstructed results are fed into the deep network for artifact correction. More specifically, we integrate the attention-gating module into U-Net pipelines, whose function is implicitly learning to emphasize relevant features beneficial for a given assignment while restraining background regions. Attention is used to combine the local feature vectors extracted at intermediate stages in the convolutional neural network and the global feature vector extracted from the coarse scale activation map. To improve the performance of our network, we fused a pre-trained ResNet50 model into our architecture. The model was trained and tested using the dataset from The Cancer Imaging Archive (TCIA), which consists of images of various human organs obtained from multiple views. This experience demonstrates that the developed functions are highly effective in removing streaking artifacts while preserving structural details. Additionally, quantitative evaluation of our proposed model shows significant improvement in peak signal-to-noise ratio (PSNR), structural similarity (SSIM), and root mean squared error (RMSE) metrics compared to other methods, with an average PSNR of 33.9538, SSIM of 0.9435, and RMSE of 45.1208 at 20 views. Finally, the transferability of the network was verified using the 2016 AAPM dataset. Therefore, this approach holds great promise in achieving high-quality sparse-view CT images.

Attention-based dual-branch deep network for sparse-view computed tomography image reconstruction.

The widespread application of X-ray computed tomography (CT) imaging in medical screening makes radiation safety a major concern for public health. Sparse-view CT is a promising solution to reduce the radiation dose. However, the reconstructed CT images obtained using sparse-view CT may suffer severe streaking artifacts and structural information loss. In this study, a novel attention-based dual-branch network (ADB-Net) is proposed to solve the ill-posed problem of sparse-view CT image reconstruction. In this network, downsampled sinogram input is processed through 2 parallel branches (CT branch and signogram branch) of the ADB-Net to independently extract the distinct, high-level feature maps. These feature maps are fused in a specified attention module from 3 perspectives (channel, plane, and spatial) to allow complementary optimizations that can mitigate the streaking artifacts and the structure loss in sparse-view CT imaging. Numerical simulations, an anthropomorphic thorax phantom, and in vivo preclinical experiments were conducted to verify the sparse-view CT imaging performance of the ADB-Net. The proposed network achieved a root-mean-square error (RMSE) of 20.6160, a structural similarity (SSIM) of 0.9257, and a peak signal-to-noise ratio (PSNR) of 38.8246 on numerical data. The visualization results demonstrate that this newly developed network can consistently remove the streaking artifacts while maintaining the fine structures. The proposed attention-based dual-branch deep network, ADB-Net, provides a promising alternative to reconstruct high-quality sparse-view CT images for low-dose CT imaging.

Best projections selection algorithm based on constrained QDEIM for sparse-views X-ray Computed Tomography

X-ray Computed Tomography (CT) is a non-destructive testing tool increasingly used by manufacturers, with growing interest in in-line testing applications. However, it is still struggling to establish itself as a standard technique due to long acquisition times. In order to meet industrial imperatives, recent research aims at reducing this acquisition time by limiting the number of views while keeping a good CT image quality. The rise of iterative reconstruction methods has made it possible to partially solve the Sparse-View CT problem thanks to the injection of regularisation terms. Furthermore, these methods also allow more freedom in the acquisition trajectories. In this work, we propose a method for reducing the number of projections without impacting the reconstruction quality by acquiring only the most relevant views. Indeed, not all views provide the same amount of information. We, therefore, present a technique for selecting views when the geometry of the inspected object is roughly known a priori. Our method is based on the Q-Discrete Empirical Interpolation Method (QDEIM) and considers the attenuation of the rays as an additional constraint.

LEARN++: Recurrent Dual-Domain Reconstruction Network for Compressed Sensing CT

Compressed sensing (CS) computed tomography (CT) has been proven to be important for several clinical applications, such as sparse-view CT, digital tomosynthesis, and interior tomography. Traditional CS focuses on the design of handcrafted prior regularizers, which are usually image-dependent and time-consuming. Inspired by recently proposed deep learning-based CT reconstruction models, we extend the state-of-the-art LEARN model to a dual-domain version, dubbed LEARN++. Different from existing iteration unrolling methods, which only involve projection data in the data consistency layer, the proposed LEARN++ model integrates two parallel and interactive subnetworks to perform image restoration and sinogram inpainting operations on both the image and projection domains simultaneously, which can fully explore the latent relations between projection data and reconstructed images. The experimental results demonstrate that the proposed LEARN++ model achieves competitive qualitative and quantitative results compared to several state-of-the-art methods in terms of both artifact reduction and detail preservation.

Self-Supervised Coordinate Projection Network for Sparse-View Computed Tomography

Sparse-view Computed Tomography (SVCT) has great potential for decreasing patient radiation exposure dose during scanning. In this work, we propose a Self-supervised COordinate Projection nEtwork (SCOPE) to reconstruct the artifact-free CT image from the acquired SV sinogram by solving the inverse problem of tomography imaging. To solve the under-determined inverse imaging problem, we first introduce an implicit neural representation (INR) network to constrain the solution space via image continuity prior. And inspired by the relationship between linear algebra and inverse problems, we propose a novel re-projection strategy to generate a dense view sinogram from the initial solution, which significantly improves the rank of the linear equation system and produces a more stable CT image solution space. Specially, the desired CT image is represented as an implicit function of the two-dimensional spatial coordinate to directly approximate the SV sinogram through the CT imaging forward model. Then, a dense-view sinogram is generated from the fine-trained INR network. The final CT reconstruction is reconstructed by applying Filtered Back Projection (FBP) to the generated dense-view sinogram. Additionally, we integrate the recent hash encoding into our SCOPE model, which efficiently accelerates the model training process. We evaluate SCOPE in parallel and fan X-ray beam SVCT reconstruction tasks. Our experiment results demonstrate that the re-projection strategy significantly improves the image reconstruction quality (+3 dB for PSNR at least). The proposed SCOPE model provides state-of-the-art reconstruction results compared to two latest INR-based methods and two well-popular supervised DL methods for the SV CT image reconstruction.

Least squares based geometric error measurement for sparse view CT: a 2D simulation study

X-ray computed tomography (CT) is considered as one of the most common techniques in non-destructive testing and is also an essential and important method in the field of dimensional measurement. For high-precision measurement task scenarios, geometric errors due to the instability of the CT motion equipment cannot be ignored and need to be accurately measured and corrected. In-situ testing of large objects such as geotechnical materials, mechanical assemblies, metal weldments and concrete specimens also requires high-precision CT imaging of their interiors to obtain information of interest. The rotation of the scanning parts for these large in-situ tests and sparse-view scanning mode also makes it difficult to measure geometric errors. This paper therefore proposes a method for simultaneous measurement of geometric errors based on a priori information for in-situ testing characteristics. This method is capable of measuring geometric errors in sparse view projections with a length accuracy of 0.1 mm and an angular accuracy of radians in 0.5 seconds per angle, as the simulation results show. The reconstruction results show that this level of geometric error measurement accuracy provides a dimensional measurement accuracy of 0.01 mm for the internal structure. The data for the simulation experiments in this paper are generated from real concrete data by noisy simulation.

Deformation measurement within lithium-ion battery using sparse-view computed tomography and digital image correlation

Electrode deformation can cause high local strain and serious capacity degradation in lithium-ion batteries (LIBs) during cycling. Risk reduction in many applications requires an understanding of the effects of the charging/discharging rate on the electrode structure during the battery life cycle. Cyclic charging/discharging experiments of wound 18 650 cylindrical LIBs were conducted at different charging/discharging rates (1C and 2C) to determine the effect of rate on electrode deformation. The charging/discharging capacity as well as battery voltage and time were analyzed during cycling. To acquire electrode deformation images and meet the requirements of computed tomography (CT) within 2 min during the charging/discharging process, sparse-view CT was performed at fixed cycle intervals. Subsequently, a sparse-view reconstruction network was proposed to generate a slice image. Finally, the electrode displacement and strain fields were calculated using the augmented Lagrangian digital image correlation algorithm. The causes of electrode deformation were analyzed and discussed from the perspective of molecular and macroscopic structure. Experimental results show that the structural similarity, peak signal-to-noise ratio and root mean square error in the reconstructed image of the axial section within the battery obtained via the proposed network were 0.9616, 38.7411 dB and 0.0108, respectively, which were better than the other methods of comparison. After 100 cycles, the capacity decay of the battery at 2C was 9.23-fold higher than that at 1C. After 100 cycles at 2C, the maximum displacement of the electrode reached 0.46 mm along the x-direction. The electrode structural deformation of the battery can be intuitively understood at different rates, which facilitates reasonable utilization and structural optimization of the battery.

Artifact Reduction for Sparse-View CT Using Deep Learning With Band Patch

Sparse-view computed tomography (CT), an imaging technique that reduces the number of projections, can reduce the total scan duration and radiation dose. However, sparse data sampling causes streak artifacts on images reconstructed with analytical algorithms. In this article, we propose an artifact reduction method for sparse-view CT using deep learning. We developed a lightweight fully convolutional network to estimate a fully sampled sinogram from a sparse-view sinogram by enlargement in the vertical direction. Furthermore, we introduced the band patch, a rectangular region cropped in the vertical direction, as an input image for the network based on the sinogram’s characteristics. Comparison experiments using a swine rib dataset of micro-CT scans and a chest dataset of clinical CT scans were conducted to compare the proposed method, improved U-net from a previous study, and the U-net with band patches. The experimental results showed that the proposed method achieved the best performance and the U-net with band patches had the second-best result in terms of accuracy and prediction time. In addition, the reconstructed images of the proposed method suppressed streak artifacts while preserving the object’s structural information. We confirmed that the proposed method and band patch are useful for artifact reduction for sparse-view CT.

A dual-domain neural network based on sinogram synthesis for sparse-view CT reconstruction

ObjectiveThe dual-domain deep learning-based reconstruction techniques have enjoyed many successful applications in the field of medical image reconstruction. Applying the analytical reconstruction based operator to transfer the data from the projection domain to the image domain, the dual-domain techniques may suffer from the insufficient suppression or removal of streak artifacts in areas with the missing view data, when addressing the sparse-view reconstruction problems. In this work, to overcome this problem, an intelligent sinogram synthesis based back-projection network (iSSBP-Net) was proposed for sparse-view computed tomography (CT) reconstruction. In the iSSBP-Net method, a convolutional neural network (CNN) was involved in the dual-domain method to inpaint the missing view data in the sinogram before CT reconstruction. MethodsThe proposed iSSBP-Net method fused a sinogram synthesis sub-network (SS-Net), a sinogram filter sub-network (SF-Net), a back-projection layer, and a post-CNN into an end-to-end network. Firstly, to inpaint the missing view data, the SS-Net employed a CNN to synthesize the full-view sinogram in the projection domain. Secondly, to improve the visual quality of the sparse-view CT images, the synthesized sinogram was filtered by a CNN. Thirdly, the filtered sinogram was brought into the image domain through the back-projection layer. Finally, to yield images of high visual sensitivity, the post-CNN was applied to restore the desired images from the outputs of the back-projection layer. ResultsThe numerical experiments demonstrate that the proposed iSSBP-Net is superior to all competing algorithms under different scanning condintions for sparse-view CT reconstruction. Compared to the competing algorithms, the proposed iSSBP-Net method improved the peak signal-to-noise ratio of the reconstructed images about 1.21 dB, 0.26 dB, 0.01 dB, and 0.37 dB under the scanning conditions of 360, 180, 90, and 60 views, respectively. ConclusionThe promising reconstruction results indicate that involving the SS-Net in the dual-domain method is could be an effective manner to suppress or remove the streak artifacts in sparse-view CT images. Due to the promising results reconstructed by the iSSBP-Net method, this study is intended to inspire the further development of sparse-view CT reconstruction by involving a SS-Net in the dual-domain method.

LRR-CED: low-resolution reconstruction-aware convolutional encoder–decoder network for direct sparse-view CT image reconstruction

Objective. Sparse-view computed tomography (CT) reconstruction has been at the forefront of research in medical imaging. Reducing the total x-ray radiation dose to the patient while preserving the reconstruction accuracy is a big challenge. The sparse-view approach is based on reducing the number of rotation angles, which leads to poor quality reconstructed images as it introduces several artifacts. These artifacts are more clearly visible in traditional reconstruction methods like the filtered-backprojection (FBP) algorithm. Approach. Over the years, several model-based iterative and more recently deep learning-based methods have been proposed to improve sparse-view CT reconstruction. Many deep learning-based methods improve FBP-reconstructed images as a post-processing step. In this work, we propose a direct deep learning-based reconstruction that exploits the information from low-dimensional scout images, to learn the projection-to-image mapping. This is done by concatenating FBP scout images at multiple resolutions in the decoder part of a convolutional encoder–decoder (CED). Main results. This approach is investigated on two different networks, based on Dense Blocks and U-Net to show that a direct mapping can be learned from a sinogram to an image. The results are compared to two post-processing deep learning methods (FBP-ConvNet and DD-Net) and an iterative method that uses a total variation (TV) regularization. Significance. This work presents a novel method that uses information from both sinogram and low-resolution scout images for sparse-view CT image reconstruction. We also generalize this idea by demonstrating results with two different neural networks. This work is in the direction of exploring deep learning across the various stages of the image reconstruction pipeline involving data correction, domain transfer and image improvement.

Dual-domain sparse-view CT reconstruction with Transformers

Purpose:Computed Tomography (CT) has been widely used in the medical field. Sparse-view CT is an effective and feasible method to reduce the radiation dose. However, the conventional filtered back projection (FBP) algorithm will suffer from severe artifacts in sparse-view CT. Iterative reconstruction algorithms have been adopted to remove artifacts, but they are time-consuming due to repeated projection and back projection and may cause blocky effects. To overcome the difficulty in sparse-view CT, we proposed a dual-domain sparse-view CT algorithm CT Transformer (CTTR) and paid attention to sinogram information. Methods:CTTR treats sinograms as sentences and enhances reconstructed images with sinogram’s characteristics. We qualitatively evaluate the CTTR, an iterative method TVM-POCS, a convolutional neural network based method FBPConvNet in terms of a reduction in artifacts and a preservation of details. Besides, we also quantitatively evaluate these methods in terms of RMSE, PSNR and SSIM. Results:We evaluate our method on the Lung Image Database Consortium image collection with different numbers of projection views and noise levels. Experiment studies show that, compared with other methods, CTTR can reduce more artifacts and preserve more details on various scenarios. Specifically, CTTR improves the FBPConvNet performance of PSNR by 0.76dB with 30 projections. Conclusions:The performance of our proposed CTTR is better than the method based on CNN in the case of extremely sparse views both on visual results and quantitative evaluation. Our proposed method provides a new idea for the application of Transformers to CT image processing.

End-to-end deep learning for interior tomography with low-dose x-ray CT

Objective. There are several x-ray computed tomography (CT) scanning strategies used to reduce radiation dose, such as (1) sparse-view CT, (2) low-dose CT and (3) region-of-interest (ROI) CT (called interior tomography). To further reduce the dose, sparse-view and/or low-dose CT settings can be applied together with interior tomography. Interior tomography has various advantages in terms of reducing the number of detectors and decreasing the x-ray radiation dose. However, a large patient or a small field-of-view (FOV) detector can cause truncated projections, and then the reconstructed images suffer from severe cupping artifacts. In addition, although low-dose CT can reduce the radiation exposure dose, analytic reconstruction algorithms produce image noise. Recently, many researchers have utilized image-domain deep learning (DL) approaches to remove each artifact and demonstrated impressive performances, and the theory of deep convolutional framelets supports the reason for the performance improvement. Approach. In this paper, we found that it is difficult to solve coupled artifacts using an image-domain convolutional neural network (CNN) based on deep convolutional framelets. Significance. To address the coupled problem, we decouple it into two sub-problems: (i) image-domain noise reduction inside the truncated projection to solve low-dose CT problem and (ii) extrapolation of the projection outside the truncated projection to solve the ROI CT problem. The decoupled sub-problems are solved directly with a novel proposed end-to-end learning method using dual-domain CNNs. Main results. We demonstrate that the proposed method outperforms the conventional image-domain DL methods, and a projection-domain CNN shows better performance than the image-domain CNNs commonly used by many researchers.