Sparsier2Sparse: Self-supervised convolutional neural network-based streak artifacts reduction in sparse-view CT images.

Abstract

Sparse-view computed tomography (CT) has attracted a lot of attention for reducing both scanning time and radiation dose. However, sparsely-sampled projection data generate severe streak artifacts in the reconstructed images. In recent decades, many sparse-view CT reconstruction techniques based on fully-supervised learning have been proposed and have shown promising results. However, it is not feasible to acquire pairs of full-view and sparse-view CT images in real clinical practice. In this study, we propose a novel self-supervised convolutional neural network (CNN) method to reduce streak artifacts in sparse-view CTimages. We generate the training dataset using only sparse-view CT data and train CNN based on self-supervised learning. Since the streak artifacts can be estimated using prior images under the same CT geometry system, we acquire prior images by iteratively applying the trained network to given sparse-view CT images. We then subtract the estimated steak artifacts from given sparse-view CT images to produce the finalresults. We validated the imaging performance of the proposed method using extended cardiac-torso (XCAT) and the 2016 AAPM Low-Dose CT Grand Challenge dataset from Mayo Clinic. From the results of visual inspection and modulation transfer function (MTF), the proposed method preserved the anatomical structures effectively and showed higher image resolution compared to the various streak artifacts reduction methods for all projection views. We propose a new framework for streak artifacts reduction when only the sparse-view CT data are given. Although we do not use any information of full-view CT data for CNN training, the proposed method achieved the highest performance in preserving fine details. By overcoming the limitation of dataset requirements on fully-supervised-based methods, we expect that our framework can be utilized in the medical imagingfield.