Abstract
The widespread application of X-ray computed tomography (CT) imaging in medical screening makes radiation safety a major concern for public health. Sparse-view CT is a promising solution to reduce the radiation dose. However, the reconstructed CT images obtained using sparse-view CT may suffer severe streaking artifacts and structural information loss. In this study, a novel attention-based dual-branch network (ADB-Net) is proposed to solve the ill-posed problem of sparse-view CT image reconstruction. In this network, downsampled sinogram input is processed through 2 parallel branches (CT branch and signogram branch) of the ADB-Net to independently extract the distinct, high-level feature maps. These feature maps are fused in a specified attention module from 3 perspectives (channel, plane, and spatial) to allow complementary optimizations that can mitigate the streaking artifacts and the structure loss in sparse-view CT imaging. Numerical simulations, an anthropomorphic thorax phantom, and in vivo preclinical experiments were conducted to verify the sparse-view CT imaging performance of the ADB-Net. The proposed network achieved a root-mean-square error (RMSE) of 20.6160, a structural similarity (SSIM) of 0.9257, and a peak signal-to-noise ratio (PSNR) of 38.8246 on numerical data. The visualization results demonstrate that this newly developed network can consistently remove the streaking artifacts while maintaining the fine structures. The proposed attention-based dual-branch deep network, ADB-Net, provides a promising alternative to reconstruct high-quality sparse-view CT images for low-dose CT imaging.
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