Social Behavior Research Articles

State of Reciprocity: The “Looping Effect” in the Circular Production of Colonial Knowledge, Social Customs, and Tax Policy in Nineteenth- and Twentieth-Century Indonesia

Abstract This article traces Hacking's “looping effect” in colonial policies and practices of taxation, coerced labour, and governance in Indonesia. It argues that knowledge production for the purpose of taxation was a two-way, interactive process which was in particular influenced by complexes of local indigenous social organization, institutions, mentalities, and behaviour as expressed through adat (Indonesian systems of political-social norms and customary law). Such patterns and systems, the article reveals, were internalized into and started working reciprocally with colonial policy, knowledge production, and administrative practices. Taxation made up and changed people, but underlying strategies to categorize and “make known” subjects were also recognized and actively used, evaded, or influenced by these subjects and by local intermediaries. Consequently, colonial knowledge created an institutional framework that reoriented the self-perception of these subjects and intermediaries, which then changed and reconditioned popular responses to the colonial state. Systems of colonial knowledge were thus modified to eventually fit the realities they were supposed to describe, influence, and legitimize, creating a looping effect between colonial, “made up,” and actual social realities.

Feasibility and Acceptability of a Self-Guided Digital Family Skills Management Intervention for Children Newly Diagnosed With Type 1 Diabetes: Pilot Randomized Controlled Trial.

Family dynamics play an important role in determining the glycemic outcomes of type 1 diabetes (T1D) in children. The time interval immediately following T1D diagnosis is particularly stressful for families, and interventions to support families in adjusting their family practices to support adjustment to and management of T1D in the months following diagnosis may improve glycemic outcomes. Self-guided digital interventions offer a sustainable model for interventions to support caregivers in learning evidence-based family management skills for adjustment to and management of T1D. We hypothesized that a self-guided, web-based, family skills management program (addressing caregiver social support as well as family problem-solving, communication, and supportive behavior change strategies) initiated at the time of T1D diagnosis would improve glycemic outcomes in children with T1D. In this study, we report on the feasibility and acceptability of this program. We prospectively evaluated a sample of 37 children newly diagnosed with T1D recruited from a pediatric endocrinology clinic. Parent participants were asked to complete web-based modules addressing social support, family problem-solving, communication, and supportive behavior change strategies. Module completion was analyzed for percentage completion, patterns of completion, and differences in completion rates by coparenting status. Qualitative open-ended feedback was collected at the completion of each module. A total of 31 (84%) of the 37 participants initiated the web-based program. Of those 31 participants, 25 (81%) completed some content and 15 (48%) completed all 5 modules. Completion rates were higher when coparenting partners engaged in the intervention together (P=.04). Of the 18 participants given a choice about the spacing of content delivery, 15 (83%) chose to have all sessions delivered at once and 3 (17%) chose to space sessions out at 2-week intervals. Qualitative feedback supported the acceptability of the program for delivery soon after T1D diagnosis. Families reported on positive benefits, including requesting future access to the program and describing helpful changes in personal or family processes for managing T1D. In this study, we found that a self-guided digital family support intervention initiated at the time of a child's T1D diagnosis was largely feasible and acceptable. Overall, rates of participation and module completion were similar to or higher than other self-guided digital prevention interventions for mental and physical health outcomes. Self-guided digital programs addressing family management skills may help prevent challenges common with T1D management and can decrease cost, increase access, and add flexibility compared to traditional interventions. ClinicalTrials.gov NCT03720912; https://clinicaltrials.gov/study/NCT03720912.

Duets convey information about pair and individual identities in a Neotropical bird

Abstract Vocal individuality is essential for social discrimination but has been poorly studied in animals that produce communal signals (duets or choruses). Song overlapping and temporal coordination make the assessment of individuality in communal signals more complex. Additionally, selection may favor the accurate identification of pairs over individuals by receivers in year-round territorial species with duetting and long-term pair bonding. Here, we studied pair and individual vocal signatures in the polyphonal duets of rufous horneros Furnarius rufus, a Neotropical bird known for its long-term pair bonds. Hornero partners engage in duets to deter territorial intruders and protect their partnership year-round, and can discern duets from neighbors versus strangers. Using a dataset of 471 duets from 43 pairs in two populations, we measured fine-scale acoustic features across different duet levels (e.g., complete duets to non-overlapping syllable parts) and analysis levels (pair or individual). Permuted linear discriminant function analyses classified pairs and individuals more accurately than expected by chance (means: 45% and 47% versus 4 and 2%). Pair identity explained more variance in the multivariate acoustic features of duets than individual or population identities. The initial frequency of the duet showed strong potential for encoding pair identity. The acoustic traits contributing most to individual vocal signatures varied between sexes, which might facilitate the simultaneous assessment of duetters’ identities by receivers. Our study indicates that vocal individuality may exist even in species with intricate and innate communal signals and elucidates the mechanisms employed by horneros in their social discrimination ability.

Epistemic tensions in R&D alliances and the role of inter-organizational management controls

Abstract Access to heterogeneous knowledge resources is suggested in the literature as an important explanation of firm innovation and performance. The exchange of knowledge, however, can be a complex managerial challenge, especially between different epistemic communities. Our research focuses on the concept of epistemic communities to illuminate the complexity of tensions that arise in heterogeneous knowledge exchange in alliances, thus filling a gap in the literature. Using the Straussian grounded theory case study approach, our research investigates the emergence of horizontal, vertical, and inter-organizational epistemic tensions and explores management controls as instruments to guide the knowledge exchange in intermediary-driven research and development alliances. We find that the source of multiple epistemic tensions is rooted in the natural social behaviors of epistemic community members and further shows how these behaviors influence the effective use of inter-organizational management controls in facilitating heterogeneous knowledge exchange.

An Interpersonal and Meta-analytic Approach to Parenting Behaviors and Adolescent Sleep.

Two dimensions of parenting behaviors-affiliative/non-affiliative and autonomy/control- are each consistently linked to adolescent sleep health. Parenting behaviors that facilitate good sleep likely involve affiliation (i.e., warmth) and some degree of parental guidance and appropriate autonomy-granting to the adolescent; however, these domains are often confounded in parenting assessments, which limits understanding and specificity of recommendations for providers and families on how to optimize adolescents' sleep. Thus, we categorized existing literature according to an interpersonal developmental framework to identify parenting behaviors most strongly linked to adolescent sleep health. Studies (k = 42) included 43,293 participants (M age = 14.84, SD age = 2.04). Structural analysis of social behavior (SASB)interpersonal coding was applied to define and operationalize parenting behaviors (independent variables). Dependent variables included measures of sleep health (i.e.,sleep regularity, duration, efficiency, latency, timing, quality, alertness/sleepiness) and sleep disturbance. The final effect size of interest for analysis was a correlation coefficient r. Optimal parenting behaviors (e.g., warm, autonomy-granting, moderately controlling) were associated with longer sleep duration, earlier bedtime, less daytime sleepiness, shorter sleep latency, and fewer sleep disturbances. Suboptimal parenting behaviors (e.g., hostile, controlling) were associated with more daytime sleepiness and more sleep disturbances. This is one of the first studies to specify that, when paired with affiliation, both moderate control and moderate autonomy-granting were associated with better adolescent sleep health. Findings indicate that the importance of parental interpersonal warmth extends into adolescence and further suggest that the interpersonal security necessary for good sleep includes appropriate use of control and autonomy-granting behaviors.

Image of Social World in Metaphors and Narratives of Adults

The image of the social world is a predictor of social behavior and its development during stable social transitivity, i.e., COVID-19 pandemic, economic crises, local military conflicts, etc. It can also be interpreted as a variable linguistic phenomenon. However, very little empirical research has featured its integral structural and content characteristics through the prism of narratives, metaphors, and social representations. The author used the methods of thematic narrative analysis and content analysis of metaphors to identify the narrative constructions used by adult subjects to describe their image of the social world. The data obtained were subjected to frequency analysis and hierarchical cluster analysis. The experiment involved 193 respondents aged 35–49 years old, employed in the city of Rostov-on-Don, Russia. In their metaphors and narratives, they described the social world as balancing between stability and dynamism, predictability and stochasticity, as well as endowed it with differentiation in the absence of universal laws. The rationality of the metaphors reflected the age identity while the subject of biographical narratives reflected the subjective adaptation to current social processes.

Calculating Relatedness: A Pedigree of Definitions.

Biology can be viewed from both an organismal and a genic perspective. A good example is W.D. Hamilton's work on inclusive fitness and kin selection, which puts relatedness at the heart of our understanding of social behavior. Relatedness mediates how much an actor should value a specific behavior's effect on a relative compared to the cost incurred to itself. Despite its key explanatory role, relatedness is also a concept marred with misunderstanding. Part of the problem has been that the term has been used in different ways by different people. To help address this, we survey the history of how relatedness has been formally modeled, paying particular attention to how it is conceptualized from both a gene-centric and an organism-centric point of view.

Lasting effects of adolescent social instability stress on dendritic morphology in the nucleus accumbens in female and male Long Evans rats

Social instability stress (SS) in adolescence in rats leads to long-lasting changes in social behaviour and reward-related behaviour relative to control rats. Given the role of the nucleus accumbens (NAc) in such behaviours, we investigated the morphology of medium spiny neurons (MSNs), which are most neurons in the NAc, in adult female and male rats exposed to SS in adolescence. Irrespective of sex, SS rats had increased number of dendritic spines in both the core and shell regions of the NAc (2.3 % and 18.1 % increase, respectively). In the core, SS rats had a 16 % reduction in the total dendritic lengths of MSNs, whereas in the shell, SS rats had a greater dendritic length closer to the soma, and particularly in SS female rats, whereas the opposite was found farther from the soma (SS 10.6 % > CTL overall). Although the extent to which such structural changes may underlie the enduring effects of SS in adolescence requires investigation, the results add to evidence that changes to the social environment in adolescence can determine adult neuronal structural.

Lactobacillus reuteri or Lactobacillus rhamnosus GG intervention facilitates gut barrier function, decreases corticosterone and ameliorates social behavior in LPS-exposed offspring

Probiotic therapy with Lactobacillus reuteri and Lactobacillus rhamnosus (LGG) demonstrates potential as an adjunctive treatment for autism spectrum disorder (ASD). In a rat model of ASD induced by lipopolysaccharide (LPS) injection during pregnancy, we evaluated the effects of these probiotics on offspring. Administration of L. reuteri or LGG for three weeks post-birth improved social deficits and reduced anxiety in LPS-exposed rats. Additionally, probiotics significantly modified short-chain fatty acid profiles, increasing butyric acid levels and decreasing propionic acid levels. They also enhanced colonic barrier integrity by upregulating tight junction proteins, including ZO-1, Occludin, and Claudin4. RNA sequencing identified differential gene expression in pathways related to inflammation, the HPA axis, and reactive oxygen species metabolism, with NADPH oxidase 1 (NOX1) emerging as a crucial gene. Validation studies confirmed that Lactobacillus strains reduced inflammatory cytokines, inhibited corticosterone secretion, increased antioxidant levels, and suppressed the NF-κB/NOX1 pathway. In an H2O2-induced oxidative stress model using Caco-2 cells, pre-treatment with L. reuteri, LGG, or NF-κB inhibitors enhanced cellular antioxidants, inhibited NF-κB/NOX1 activation, and improved barrier function. Overall, L. reuteri and LGG administration improved social behavior, bolstered colonic barrier function, and mitigated HPA axis overactivation in LPS-exposed rats, while also alleviating oxidative stress in the colon and Caco-2 cells. These findings suggest that L. reuteri and LGG have substantial clinical potential for ASD treatment by targeting multiple pathophysiological mechanisms, including inflammation, HPA axis dysregulation, and oxidative stress, thereby presenting a promising adjunctive therapeutic strategy for enhancing social behavior and gut health in ASD.

Prelimbic cortex perineuronal net expression and social behavior: Impact of adolescent intermittent ethanol exposure

Adolescent intermittent ethanol (AIE) exposure in rats leads to social deficits. Parvalbumin (PV) expressing fast-spiking interneurons in the prelimbic cortex (PrL) contribute to social behavior, and perineuronal nets (PNNs) within the PrL preferentially encompass and regulate PV interneurons. AIE exposure increases PNNs, but it is unknown if this upregulation contributes to AIE-induced social impairments. The current study was designed to determine the effect of AIE exposure on PNN expression in the PrL and to assess whether PNN dysregulation contributes to social deficits elicited by AIE. cFos-LacZ male and female rats were exposed every other day to tap water or ethanol (4 g/kg, 25% w/v) via intragastric gavage between postnatal day (P) 25–45. We evaluated neuronal activation by β-galactosidase expression and PNN levels either at the end of the exposure regimen on P45 and/or in adulthood on P70. In addition, we used Chondroitinase ABC (ChABC) to deplete PNNs following adolescent exposure (P48) and allowed for PNN restoration before social testing in adulthhod. AIE exposure increased PNN expression in the PrL of adult males, but decreased PNNs immediately following AIE. Vesicular glutamate transporter 2 (vGlut2) and vesicular GABA transporter (vGat) near PNNs were downregulated only in AIE-exposed females. Gene expression of PNN components was largely unaffected by AIE exposure. Removal and reestablishment of PrL PNNs by ChABC led to upregulation of PNNs and social impairments in males, regardless of adolescent exposure. These data suggest that AIE exposure in males upregulates PrL PNNs that likely contribute to social impairments induced by AIE.

Family Frugality Scale: Development, Validation, and Usage of an Implicit Financial Socialization Modeling Measure

The Family Frugality Scale (FFS) was developed to retrospectively measure an individual’s perception of the degree to which their family was frugal in the management of resources while the individual was growing up. Research in financial socialization has increasingly noted the significance of family and parental socialization modeling behaviors. This scale is unique in that it focuses on a specific family socialization behavior that young adults can reflect on from their adolescence—family frugality—one that may or may not have been implicitly modeled in their family during their younger years. The scale items were constructed using a combination of existing scales, qualitative focus group analysis, survey data from a national sample of 1,245 young adults between the ages of 18 and 34 years, and structural equation modeling. Multiple test results show that the FFS was reliable and valid and can be used to evaluate its relationships with other individual and familial financial behaviors.

Interoception mediates the association between social support and sociability in patients with major depressive disorder.

Interoception dysfunction has an important impact on the onset and development of major depressive disorder (MDD). Social support serves as a protective factor against MDD, and sociability also plays a significant role in this condition. These interconnected constructs-social support and sociability-play pivotal roles in MDD. However, no research on the mechanisms underlying the associations between social support and sociability, particularly the potential role of interoception, have been reported. To investigate the mediating effect of interoception between social support and social ability and to explore the independent role of social support in sociability. The participants included 292 patients with MDD and 257 healthy controls (HCs). The patient health questionnaire 9, the multidimensional assessment of interoception awareness, version 2 (MAIA-2), the social support rating scale (SSRS), and the Texas social behavior inventory (TSBI) were used to assess depression, interoception, social support, and sociability, respectively. A mediation analysis model for the eight dimensions of interoception (noticing, not distracting, not worrying, attention regulation, emotional awareness, self-regulation, body listening, and trust), social support, and sociability were established to evaluate the mediating effects. A partial correlation analysis of eight dimensions of the MAIA-2, SSRS, and TSBI scores, with demographic data as control variables, revealed pairwise correlations between the SSRS score and both the MAIA-2 score and TSBI score. In the major depression (MD) group, the SSRS score had a positive direct effect on the TSBI score, while the scores for body listening, emotional awareness, self-regulation, and trust in the MAIA-2C had indirect effects on the TSBI score. In the HC group, the SSRS score had a positive direct effect on the TSBI score, and the scores for attention regulation, emotional awareness, self-regulation, and trust in the MAIA-2C had indirect effects on the TSBI score. The proportion of mediators in the MD group was lower than that in the HC group. Interoceptive awareness is a mediating factor in the association between social support and sociability in both HCs and depressed patients. Training in interoceptive awareness might not only help improve emotional regulation in depressed patients but also enhance their social skills and support networks.

Sex-specific co-developmental trajectories of childhood victimization among elementary school students: Relations to social behavior

This study aimed to identify sex-specific co-developmental trajectories of multiple forms of childhood victimization: family maltreatment (FM), psychological maltreatment by teachers (PMT), and peer victimization (PV), and their relations to prosocial and delinquent behaviors among elementary school students. A total of 4378 Chinese elementary school students (Mage = 9.93; SD = 0.92; 55.14% boys) participated in assessments on five occasions, using six-month intervals. Parallel process latent class growth model analyses revealed three trajectories for boys: Congruent-low (75.64%), High-PV, Moderate-FM and PMT (14.62%), and Moderate-PV, High-FM and PMT (9.74%). Similarly, girls exhibited three trajectories: Congruent-low (81.11%), Moderate-PMT, High-FM and PV (10.54%), and High-PMT, Moderate-FM and PV (8.35%). The results indicated that boys were more susceptible than girls to three forms of childhood victimization. Furthermore, boys were especially vulnerable to co-occurring FM and PMT. In contrast, girls were more vulnerable to co-occurring FM and PV. Additionally, after experiencing childhood victimization, girls showed a greater hindrance in prosocial behavior development, whereas boys exhibited a more significant increase in delinquent behavior. These findings underscore the importance of considering sex differences in understanding multiple forms of childhood victimization and provide important insights for prevention and intervention efforts.

Winning with Losses: The Surprising Success of Negative Strategies in Social Interaction Behavior.

In the vast network of social interactions and behaviors, it is common to find certain schemes that, on their own, might appear counterproductive to societal progress. When observed in isolation, these schemes often seem to hinder more than they help. However, due to society's complexity, the hidden potential of combining these seemingly detrimental schemes often goes unnoticed. Here, we investigate two such social behaviors, reputation and reciprocity, and their role in explaining Darwin's survival of the fittest, examining how these fundamental principles govern individual interactions and shape broader social dynamics. We outline the dynamics of these two social behaviors and underline the importance of combined strategies in enhancing group welfare and contributing to interdisciplinary research in social physics.

Social cognition in adults with neurofibromatosis type 1.

Adult patients with the genetic disease neurofibromatosis type 1 (NF1) frequently report social difficulties. To date, however, only two studies have explored whether these difficulties are caused by social cognition deficits, and these yielded contradictory data. The aim of the present study was to exhaustively assess social cognition abilities (emotion, theory of mind, moral reasoning, and social information processing) in adults with NF1, compared with a control group, and to explore links between social cognition and disease characteristics (mode of inheritance, severity, and visibility). We administered a social cognition battery to 20 adults with NF1 (mean age = 26.5 years, SD = 7.4) and 20 healthy adults matched for sociodemographic variables. Patients scored significantly lower than controls on emotion, theory of mind, moral reasoning, and social information processing tasks. No effects of disease characteristics were found. These results appear to confirm that adults with NF1 have a social cognition weaknesses that could explain, at least in part, their social difficulties, although social abilities are not all impaired to the same extent. Regarding the impact of the disease characteristics, the patient sample seemed slightly insufficient for the power analyses performed. Thus, this exploratory study should form the basis of further research, with the objective of replicating these results with larger and more appropriately matched samples.

Transient CSF1R inhibition ameliorates behavioral deficits in Cntnap2 knockout and valproic acid-exposed mouse models of autism

Microglial abnormality and heterogeneity are observed in autism spectrum disorder (ASD) patients and animal models of ASD. Microglial depletion by colony stimulating factor 1-receptor (CSF1R) inhibition has been proved to improve autism-like behaviors in maternal immune activation mouse offspring. However, it is unclear whether CSF1R inhibition has extensive effectiveness and pharmacological heterogeneity in treating autism models caused by genetic and environmental risk factors. Here, we report pharmacological functions and cellular mechanisms of PLX5622, a small-molecule CSF1R inhibitor, in treating Cntnap2 knockout and valproic acid (VPA)-exposed autism model mice. For the Cntnap2 knockout mice, PLX5622 can improve their social ability and reciprocal social behavior, slow down their hyperactivity in open field and repetitive grooming behavior, and enhance their nesting ability. For the VPA model mice, PLX5622 can enhance their social ability and social novelty, and alleviate their anxiety behavior, repetitive and stereotyped autism-like behaviors such as grooming and marble burying. At the cellular level, PLX5622 restores the morphology and/or number of microglia in the somatosensory cortex, striatum, and hippocampal CA1 regions of the two models. Specially, PLX5622 corrects neurophysiological abnormalities in the striatum of the Cntnap2 knockout mice, and in the somatosensory cortex, striatum, and hippocampal CA1 regions of the VPA model mice. Incidentally, microglial dynamic changes in the VPA model mice are also reported. Our study demonstrates that microglial depletion and repopulation by transient CSF1R inhibition is effective, and however, has differential pharmacological functions and cellular mechanisms in rescuing behavioral deficits in the two autism models.

The impact of touristic whale-watching on Delphinus Delphis and Tursiops truncatus in the Algarve Coast: Combining acoustic analysis and land observations

Touristic whale watching (WW) is an important socioeconomic activity worldwide. Recently, short and long-term impacts caused by WW have been reported for several cetacean species, including Delphinus delphis and Tursiops truncatus, the two most observed species in Portugal. Most of the operations in mainland Portugal are concentrated on the South Coast (Algarve). However, despite their importance for the region, studies focused on the impact of this activity on the animals are still scarce. We used acoustic behaviour analysis and land-based observations to determine the alterations in the vocalization patterns of these animals caused by WW vessels and the length of exposure to this stressor. We found WW presence significantly altered five out of six acoustic parameters of whistles, whistle rate, and whistle type distribution for D. delphis, whereas T. truncatus exhibited significant changes in three acoustic parameters. Conversely, T. truncatus significantly reduced echolocation click rates, while D. delphis did not show significant changes. We also found that the Central region of this coast is the most affected, with animals exposed to WW vessels for up to 38.9% of daylight hours. Furthermore, 66.7% of the observation time in this area had several vessels that exceeded the limit established by law. These results suggest that our study species are impacted by WW, while D. delphis is more affected during social behaviours, and T. truncatus is more affected during foraging activities. Both behaviours are biologically significant, and their disturbance might, in the long term, lead to adverse effects at the population level by decreasing reproductive success and fitness. A gap in knowledge, inadequate legislation and compliance issues threaten the development of a sustainable WW industry in the Algarve and might endanger local populations, therefore immediate attention is needed.

Векторы социальной психологии: опережая время (к 100-летию со дня рождения Галины Михайловны Андреевой)

<p style="text-align: justify;"><strong>Objective.</strong> Analysis of the main methodological and theoretical directions in social psychology developed by Professor Galina Mikhailovna Andreyeva, one of the founders of Russian social psychology; consideration of the key problems of modern social psychology. <br><strong>Background. </strong>The vectors of scientific knowledge identified by G.M. Andreyeva and the problems she developed in the field of social psychology have become general methodological principles in various fields of psychological science. Among them there are the problems of joint activity and communication, which have become the basis for the study of social groups and personality. A fundamental principle of the new paradigm of social psychology offered by G.M. Andreyeva, – the issues of the influence of the social context and the influence of social changes on the formation (construction) of a person's world image and his social behavior. Significant moments in the field of social cognition created by G.M. Andreyeva are highlighted. The potential of her main ideas in modern psychology is shown. The main biographical data of Galina Andreyeva are presented, showing her life path and significant for the creation of the G.M. Andreyeva School of Social Psychology at Moscow University. <br><strong>Methodology.</strong> The article uses methods of deductive analysis; methods of historical and psychological hermeneutics. <br><strong>Conclusions.</strong> The main scientific ideas of G.M. Andreeva not only became the theoretical and methodological basis for understanding and explaining the fundamental problems of socio-psychological knowledge, but also made a huge contribution to understanding the ongoing social changes.</p>

How Does Understanding of Social Situations and Other's Intention Contribute to Idiom and Irony Comprehension in Autism Spectrum Disorder?

Background/Objectives: Figurative language is a central tool for enriching spoken and written languages, and it is important for building social relationships. Difficulties in figurative language understanding may impair social adjustment. Some studies have found more gaps in the understanding of irony and idioms among children with autism spectrum disorder (ASD) compared to those of their peers with typical development (TD). To date, no studies have examined the relationship between the ability to understand social situations (as a separate ability) and the ability to understand irony and idioms. The present study examined the roles of theory of mind (ToM) and social situation understanding in the comprehension of idioms and ironic criticism. Methods: The current study included 58 participants aged 8-11, including 28 children with high-functioning ASD and 30 children with TD matched by age, gender, and nonverbal intelligence. All the participants completed a ToM questionnaire that assesses their understanding of others' intentions, as well as a questionnaire pertaining to their comprehension of social situations, ironic criticism, and idioms. Results: TD children outperformed the autistic children in idiom and irony understanding, as well as in ToM and social situation understanding. Understanding social situations and ToM contributed to idiom and irony understanding, with ToM ability uniquely contributing to irony (but not to idiom) understanding. Path analysis revealed that social cognitive abilities mediated the link between group affiliation and vocabulary, affecting figurative language comprehension. Conclusions: The present study demonstrates that social cognition skills influence the ability to understand ironic criticism and idioms, mediating the association between vocabulary and figurative language comprehension.

Effect of small dose esketamine on perioperative neurocognitive disorder and postoperative depressive symptoms in elderly patients undergoing major elective noncardiac surgery for malignant tumors: A randomized clinical trial.

Perioperative neurocognitive disorder and postoperative depressive symptoms are significant complications after surgery. Studies have indicated that esketamine possesses neuroprotective and antidepressant qualities. This trial included 209 patients aged 60 to 86 years undergoing tumor resection who received esketamine (Group E) or not (Group C) during and after surgery. In group E, patients were given an intravenous dose of 0.5 mg/kg of esketamine 10 minutes after induction of general anaesthesia. In addition, esketamine (2 mg/kg) in combination with sufentanil was used for PCIA during 48 hours postoperatively. On the other hand, saline was used as a substitute for esketamine in group C. Cognitive function was evaluated using neuropsychological tests and telephone interview for cognitive status-modified, and symptoms of depression were assessed using Hamilton Depression Rating Scale 17. Compared to Group C, patients in Group E exhibited lower rates of depressive symptoms at 3, 7, and 90 days post-surgery (53.9% vs 67.7%, 26.3% vs 47.9%, and 13.3% vs 28.4%). Group E also showed decreased time for Trail Making Test on days 7 and 90. However, there were no significant differences in the incidence of delirium 1 to 5 days post-surgery or cognitive impairment 90 days post-surgery between the 2 groups (12.1% vs 10.9% and 8.4% vs 9.7%). Intraoperative low-dose esketamine and postoperative low-dose esketamine combined with sufentanil for patient-controlled intravenous analgesia has been shown to improve postoperative analgesia, alleviate postoperative depressive symptoms, and aid in the recovery of social executive ability. However, this approach did not reduce the incidence of postoperative delirium or postoperative cognitive dysfunction.