The article is devoted to the analysis of peculiarities of formation of business social responsibility. Increasing the level of competition in the domestic market promotes the search for new managerial decisions, one of which is the introduction of social responsibility in the activities of domestic enterprises. An important issue today is the study of the benefits of implementation and effective approaches to the implementation of social responsibility of business for domestic enterprises as an integral part of entrepreneurship in the system of national economy and justification of the benefits of such activities. The approaches of scientists and international organizations to the concept of social responsibility are researched. The advantages of introduction of business social responsibility in the national practice are determined. The effective approaches to realization of business social responsibility for domestic enterprises are substantiated as an integral part of entrepreneurship in the system of national economy. The components of levels of business social responsibility are systematized. The concept of business social responsibility is considered. The concept of business social responsibility is effective and tested by international companies as a tool for sustainable development of both society and the country as a whole. Social responsibility is a connecting link between sustainable development of society and the sustainable development of the organization. An important step in its formation is state regulation and support. State policy in the field of social responsibility is an integral part of its systemic development. Such a policy stimulates the dissemination of institutional norms of social responsibility, creates conditions for the business of social investment; it is a series of legislative and additional initiatives aimed at the business community and is realized largely due to the active position of the representatives of society. The necessity of development of effective state policy in the field of social responsibility is emphasized, in this connection the directions of stimulation by the state of development of social programs are highlighted. The practical significance of the results obtained is that their application will contribute to the development of the enterprise and the country as a whole, at the expense of the social benefits received from the introduction of social responsibility at domestic enterprises.