The modern engineering products must fulfill the increasing requirements to the vibroacoustical behavior of the components and the system. For many applications such as automotive engineering, where light-weight design is desired, passive measures for noise and vibration reduction have reached certain limits. For this reason, active techniques for structural vibration reduction are becoming increasingly important in this field of applications. Commonly, actively or adaptively controlled structural systems consist of a large number of components with various functionalities. As the complexity of the systems increases, reliability and robustness studies become a more complicated task. The knowledge of parameter effects and their interactions is important for the reliability study and the design optimization of such systems. Sensitivity analysis can help the system designers to understand interactions between the system components and identify the important parameters with significant overall influences on the system performance. In this paper, several approaches to sensitivity analysis are applied for a smart structure system with active vibration control. Through these analyses, the influences of the system parameters and control algorithms on the performance of active vibration reduction are investigated. An improvement of the robustness of the active system by using adaptive control will be shown.