New reflector structure (RS) based on ultra-wide stopband single-layer frequency selective structure (FSS) for mid-band sub-6 GHz 5G applications is designed. The proposed RS is arranged into array of 7 × 7-unit cell of FSS elements for antenna gain and front-to-back ratio enhancement. The single antenna element of volume 30 × 20 × 1.6 (in mm3) consists of a dual-quarter-circular truncated edge-fed rectangular slot (R-slot) loaded rectangular patch (R-patch) antenna with degraded ground structure (DGS) to operate at 3.6 GHz mid-band sub-6 GHz 5G and 5.8 GHz WBAN band. The proposed unit cell FSS element, the RS of volume 55.5 × 55.5 × 13.2 (in mm3) and the associated antenna are designed on lossy thin FR-4 substrate material and investigated numerically using commercial computer simulation technology microwave studio (CST-MS) software. The studied dual-structure based RS made with array of single-layer FSS and monopole R-patch antenna is fabricated and measured. The measured impedance bandwidth (IBW) of 48.28% (3.06–4.85 GHz) and 86.20% (5–10 GHz), peak gain of 5.36 and 7.45 dBi, radiation efficiency of 67.11% and 80.16%, and front-to-back ratio of 12.23 dB and 22.84 dB are achieved at the resonant frequencies 3.5 and 5.8 GHz respectively. The FSS reflector associated with the dual-band monopole R-patch antenna performances are in good agreement with the portable wireless applications requirements.