With the rapid development of 5G infrastructure, cloud computing and other technologies to enhance the rapid development of autonomous vehicles. How to quickly, safely and efficiently test and evaluate the autonomous vehicles is the only way for that to have the ability to drive on real public road. This paper build a set of automatic driving simulation test system based on digital twin technology, describing the necessary steps taken for the system design, system implementation, and testing of a autonomous vehicle. In the system the real traffic scene in the digital space re-emerged, to achieve the real vehicle running in the real environment, while mapping to the virtual environment to achieve the vehicle in the loop, making it possible to define driving test scenarios for different types of tractor and trailer combinations and providing the free test site for autonomous vehicles. At the same time, the system provides an open interface, to verify and test various autonomous algorithms. The sensor device of the tested autonomous system is flexibly configured, and the test cost is low and the efficiency is high.