Voltage Shift Research Articles

Fundamental understanding of quantum confinement effect on gate oxide reliability for gate-all around field-effect transistor

Gate oxide reliability has become a significant concern for emerging technology nodes, particularly as transistors continue to scale down. Quantum confinement effects in nano-scaled devices complicate the trapping dynamics near the interface. Although these behaviors can be modeled using density-functional theory (DFT) and Marcus theory, a more efficient method is essential for characterizing critical reliability issues at the nano-device level. This paper presents a pioneering numerical study that employs a Bohm potential and Marcus theory, examining carrier concentration decay near the channel/oxide interface to evaluate the charge-trapping process using density-gradient coupled Poisson equations. This approach incorporates vital quantum corrections to classical studies. Key physics-based parameters are initially derived from DFT calculations and subsequently calibrated against experimental data. Our findings indicate that charge trap rates decrease with carrier density at the interface, ultimately affecting the device's threshold voltage shift.

Investigation of total ionizing dose effects on SOI FinFETs at elevated temperatures

Abstract The synergistic effects of total ionization dose (TID) and high temperature (HT) are investigated for n-type Silicon-on-Insulator (n-SOI) FinFETs. Experimental results reveal that both HT and TID will lead to a negative shift in threshold voltage (ΔV TH) in n-SOI FinFETs. While the ΔV TH induced by the synergistic effects is smaller than the sum of the ΔV TH shifts caused by TID and HT effects individually. Theoretical analysis suggests that the weaken degradation phenomenon can be attributed to the decrease of shallow-level electron traps in the HfO2 layer of stacked gate oxide. Based on this analysis, an analytical model is developed to simulate the synergistic effects of TID and HT, which has been validated by both experimental results and TCAD simulations. The proposed model enables accurate prediction of the potential distribution within the fin, allowing for precise calculation of V TH variations under HT and TID irradiation.

Al modification layer method for enhancing InAlZnO transistors

In this work, a surface engineering method is proposed to boost electrical performance and stability of the InAlZnO (IAZO) transistors, of which an Al modification layer is deposited on surface of the IAZO channel layer. Through analysed by transmission electron microscope and X-ray photoelectron spectroscopy, the IAZO thin film with Al modification layer undergoes a reduction reaction to generate more oxygen vacancies. Hall effects measurement further demonstrates that IAZO thin films with Al modification layer exhibit higher carrier concentrations than the ones without Al modification layer. The IAZO transistors with Al modification layer exhibit better performance and stability, including a field-effect mobility of 4.36 cm2 V−1s−1 (an improvement of about three-fold), a small subthreshold swing of 105.23 mV/decade, a high on-to-off current ratio greater than 107, and a threshold voltage shift of less than 0.50 V under positive and negative gate bias stress. Moreover, the IAZO transistors with Al modification layer demonstrate high thermal stability under 400 °C for 120 min in air atmosphere. Based on this method, the IAZO inverters have been implemented with high voltage gain of 87.55 V/V. This surface engineering technology paves the way for application of high-performance oxide transistors for advanced monolithic three-dimensional integration.

Improved p-GaN/AlGaN/GaN HEMTs with magnetronsputtered AlN cap layer

In this paper, a low temperature sputtered AlN cap-layer p-GaN HEMT with high gate breakdown and improved reliability is realized. XPS test shows that the valence band offset of p-GaN and low-temperature magnetron sputtered AlN is 1.2 eV, which successfully suppresses the gate leakage current and greatly improves the gate reliability. Low capacitance–voltage hysteresis and small pulsed threshold voltage shift predict good AlN/p-GaN interface quality. The threshold voltage of the AlN/p-GaN HEMT is improved from 0.61 V to 0.82 V compared to the conventional p-GaN HEMT with tungsten Schottky gate (W/p-GaN HEMT), the DIBL decrease from 34.4 mV/V in W/p-GaN HEMT to 1.1 mV/V in AlN/p-GaN HEMT. The gate forward and reverse leakage is significantly suppressed, and the gate forward breakdown voltage is improved to 17 V. The gate operating range is improved from 7 V to 12 V, and the ID/IG under saturation state is improved from 104 to 107. In addition, a smaller on-resistance of 67.5 Ω·mm was obtained, which is 15.3 % lower than that of the W/p-GaN HEMT, minimizing on-state loss. The gate leakage mechanism of the AlN/p-GaN HEMT is mainly dominated by the PF emission in the medium gate voltage range. Based on this leakage mechanism, the maximum forward VG for a ten-year lifetime was extracted as 6.8 V at room temperature at a failure level of 63.2 % for the AlN/p-GaN HEMT, while this value for W/p-GaN HEMT is 5.4 V. In addition, the AlN cap layer attenuates the depletion region of metal/p-GaN by the gate Schottky metal, which keeps the GaN channel better depleted, thus keeping a higher off-state breakdown voltage. These results demonstrate the good potential of magnetron sputtering AlN as a low-cost, methodologically simple growth method for the commercial use of p-GaN HEMTs.

Label-Free Electrochemical Sensor Sensitivity Enhancement Using Field Effect Transistors: Fluoride Ions for Fuel Cell Degradation Analysis

In the context of proton exchange membrane fuel cells, precise monitoring of fluoride ions in the effluent water is crucial. Associated with the fluoride ion accumulation, membrane degradation and reduction of fuel cell efficiency arise. This study focuses on developing extended gate field-effect transistors (EGFET) sensors for real-time monitoring of fluoride ion concentrations. High sensitivity and specificity in detecting the concentration of fluoride ions using both N-type (TN0702) and P-type (LP0701) metal-oxide-semiconductor field-effect transistors (MOSFET) were achieved. The transfer characteristics (Id vs Vgs) owere thoroughly examined across a range of fluoride concentrations from parts per million (ppm) to parts per billion (ppb). N-type MOSFET-based sensors showed a distinct decrease in drain current (Id) with increasing fluoride concentration. With fluoride concentrations changed, the P-type MOSFET exhibited a notable shift in the threshold voltage (Vgs). A robust linear relationship was observed on calibration curves with R2 values exceeding 0.90 between the natural logarithm of fluoride concentration (lnC) and gate-source voltage (Vgs). This work demonstrates that MOSFET can significantly enhance the sensitivity of electrochemical sensors without complex labeling processes. The improvement has a future in the miniaturization of cost-effective sensor systems for fuel cell applications, facilitating real-time performance and degradation monitoring.

Impact of bias stress and endurance switching on electrical characteristics of polycrystalline ZnO-TFTs with Al2O3 gate dielectric

Abstract This study experimentally investigates electrical characteristics and degradation phenomena in polycrystalline zinc oxide thin-film transistors (ZnO-TFTs). ZnO-TFTs with Al2O3 gate dielectric, Al-doped ZnO (AZO) source–drain contacts, and AZO gate electrode are fabricated using remote plasma-enhanced atomic layer deposition at a maximum process temperature of 190 °C. We employ positive bias stress (PBS), negative bias stress (NBS), and endurance cycling measurements to evaluate the ZnO-TFT performance and examine carrier dynamics at the channel-dielectric interface and at grain boundaries in the polycrystalline channel. DC transfer measurements yield a threshold voltage of −5.95 V, a field-effect mobility of 53.5 cm2/(V∙s), a subthreshold swing of 136 mV dec−1, and an on-/off-current ratio above 109. PBS and NBS measurements, analysed using stretched-exponential fitting, reveal the dynamics of carrier trapping and de-trapping between the channel layer and the gate insulator. Carrier de-trapping time is 88 s under NBS at −15 V, compared to 1856 s trapping time under PBS at +15 V. Endurance tests across 109 cycles assess switching characteristics and temporal changes in ZnO-TFTs, focusing on threshold voltage and field-effect mobility. The threshold voltage shift observed during endurance cycling is similar to that of NBS due to the contrast in carrier trapping/de-trapping time. A measured mobility hysteresis of 19% between the forward and reverse measurement directions suggests grain boundary effects mediated by the applied gate bias. These findings underscore the electrical resilience of polycrystalline ZnO-TFTs and the aptitude for 3D heterogeneous integration applications.

The degradation mechanism of high power S-band AlGaN/GaN HEMTs under high temperature

Abstract The radio frequency (RF) degradation mechanism under high temperature is proposed in this paper. The saturated output power (P sat), power added efficiency (PAE) and gain of the HEMTs deteriorate significantly under high power dissipation operation conditions, which contribute to an elevation of the junction temperature (T j). The high T j causes a negative shift of the threshold voltage and a reduction of electron mobility, as well as enhancing the trapping effects of the devices. As a result, the P sat and PAE of the high-power HEMTs (P sat = 152 W) decreased by 0.76 dB and 8.3%, respectively, which is more severe compared to low-power HEMTs (P sat = 20 W), where P sat and PAE reduced by 0.16 dB and 3.1% when the operation temperature was increased from 25 °C to 150 °C. By increasing the gate-to-drain distance from 1.625 to 2.175 μm, drain current stability and high temperature reverse bias reliability are improved. The results demonstrate that the trapping effect can be suppressed by decreasing the electric field under the gate; therefore, the RF output characteristics are boosted by 1.2 W, 1 dB and 2.6% for a device with gate width of 11.52 mm.

Mechanisms and models of interface trap annealing in positively-biased MOS devices

Abstract We propose a hydrogen anion (H$^-$) passivation mechanism of the interface trap annealing (ITA) in positively-biased metal-oxide-semiconductor (MOS) devices. It is demonstrated that, the protons (H$^+$) released in SiO$_2$ due to H$_2$ cracking on oxide traps can migrate into Si at relatively high temperature, therefore passivating the interfacial $P_b$ centers by capturing two electrons provided by the positive bias. This new mechanism explains the elimination temperature of about 100$^\circ$C in experiments, which is much lower than temperature above 220$^\circ$C predicted by the traditional H$_2$ passivation mechanism. We also derive analytic models of the ITA, based on the coupling transformation dynamics of oxide and interface traps, as well as the concept of hierarchically constrained dynamics in glassy materials. These models can universally describe a generation-to-elimination transition of $P_b$, and predict the enhanced elimination of $E'_\gamma$ as the annealing temperature is elevated. Moreover, we demonstrate that, the defect annealing models can be applied to analysis the nonmonotonic temperature dependence of the annealing of threshold voltage shift in nMOS devices. Our findings provide a theoretical basis for achieving the low temperature elimination of interface traps, and for setting the high temperature stages of accelerated aging and damage evaluations of MOS devices.

Thermal atomic layer deposition-processed InHfZnO thin film transistors with excellent stability

In recent years, the downscaling of transistors has sparked considerable interest in the advancement of amorphous oxide semiconductors, particularly indium-hafnium-zinc oxide (IHZO) has remarkable potential in applications such as high-resolution displays and 3D NAND. For the first time, we propose the fabrication of IHZO thin film transistors (TFTs) via thermal atomic layer deposition (TH-ALD). The preparation, electrical properties, and stability of IHZO TFTs are investigated. The performance of TFT deposited at 250 °C and annealed in N2 atmosphere at 300 °C exhibits a high field-effect mobility (μ) of 22.53 cm2/Vs, a high Ion/Ioff of ∼107, a low threshold voltage (Vth) of 0.15 V, and a minimum subthreshold swing (SS) of 0.24 V/decade. Furthermore, the threshold voltage shifts (ΔVth) in TFTs annealed in N2 and O2 are 0.31 and 0.16 V, respectively. These enhancements are attributed to the defects suppression and remaining ionized oxygen vacancies result in increased electron concentration in N2-annealed films. In comparison, O2 annealing causes a reduction in field effect mobility but concurrently enhances stability due to the direct passivation of defects, which leads to fewer oxygen vacancies. Additionally, Hf content can also impact the performance of TFT devices, even a small addition of Hf also results in the effective reduction of the carrier concentration. These findings provide valuable insights into the device mechanism of IHZO TFTs, presenting a novel avenue for comprehending and augmenting their overall performance.

Electron trapping in HfO2 layer deposited over a HF last treated silicon substrate

Electron trapping in HfO2-based MOS structures was studied through pulsed capacitance-voltage (C-V) technique. 10 nm HfO2 layer was deposited by atomic layer deposition over a HF last treated Si substrate. The C-V curves were observed to shift to positive voltages driven by the positive applied voltage along the pulses, consistent with electron trapping due to tunneling transitions between the substrate and pre-existing defects within the oxide and the subsequent lattice relaxation through electron-phonon interaction. The dependences of the voltage shift for a given capacitance value (ΔVC) with stress bias and time, allowed to distinguish two mechanisms. An initial trapping process occurs for times shorter than the microsecond, probably associated with a thin non-stoichiometric SiOx interfacial layer, which is followed by a trapping process that starts after tens of μs and progressively slowed down, associated with traps within the HfO2 layer. Numerical simulations yield for the HfO2 traps an energy of 1.3 eV below the conduction band edge, decreasing exponentially with the distance from the Si interface with a characteristic length of 1.7 nm; and phonon and relaxation energies of 50 meV and 1 eV, respectively. These physical parameters are consistent with previous reports of electron trapping in HfO2 layers deposited on a controlled interfacial layer, suggesting that trapping properties of defects inside the HfO2 layer are insensitive to the treatment of the Si surface before HfO2 deposition. On the other hand, the observed large initial trapping suggests that the non-controlled SiOx interfacial region is more defective than a controlled one.

Microscopic Origin of Polarity-Dependent VTH Shift in Amorphous Chalcogenides for 3D Self-Selecting Memory.

Ovonic threshold switching (OTS) selectors based on amorphous chalcogenides can revolutionize 3D memory technology owing to their self-selecting memory (SSM) behavior. However, the complex mechanism governing the memory writing operation limits compositional and device optimization. This study investigates the mechanism behind the polarity-dependent threshold voltage shift (ΔVTH) through theoretical and experimental analyses. By examining the physical principles of threshold switching and conducting defect state analysis, the ΔVTH as a memory window is confirmed to be attributed to the dynamics of charged defects and their gradient near electrodes, influenced by the nonuniform electric field after threshold switching. This study provides critical insights into the operational mechanism of OTS-based SSM, known as selector-only memory, highlighting its advantages for developing high-density, low-cost, and energy-efficient memory technologies in the artificial intelligence era.

Characterization and modeling of the mobility, threshold voltage, and subthreshold swing in p-GaN gate HEMTs at cryogenic temperatures

This study presents a comprehensive investigation of the electrical properties of p-GaN gate HEMT devices under cryogenic operations, spanning a temperature range from 300 K all the way down to 10 K. We report achievement of a low sub-60 mV/dec sub-threshold swing (SS) (33.2 mV/dec at 10 K), a high ION/IOFF ratio (∼3.5 × 1010 at 10 K), and a remarkable ID,max (∼358 mA/mm at 10 K) in p-GaN gate HEMTs operating under cryogenic conditions. Furthermore, the mobility, threshold voltage shifts, and SS characteristics at cryogenic temperatures are modeled in p-GaN HEMTs. In summary, p-GaN gate HEMTs are promising for cryogenic applications due to their low SS, high gm,max, impressive ION/IOFF ratio, and substantial ID,max. Furthermore, the modeling achieved in this work can pave the way for future characteristic prediction in p-GaN HEMTs at cryogenic temperatures.

Electron Irradiation on Metal Oxide Silicon Field Effect Transistors in Space Applications

The space environment is hostile to most semiconductor electronic devices and components used for space applications. The radiation generally encountered in space are α, β, γ, x-ray, energetic electrons, protons, neutrons and ions of various kinds. Especially the Van Allen Belts consist of high energy electrons which are in continuous motion. Satellites systems operating in Low Earth Orbits (LEO) are prone to get exposed to high energy electrons. This paper describes the effect of electron beam irradiation on MOSFETs planned for space applications. The devices selected for the study are 2N6768 n- channel MOSFETs (JANTXV) procured from ISAC, Bangalore. The decapped MOSFETS are exposed to a beam of electrons for various doses ranging from 50 Gy to 10 KGy in the electron energy range 7 – 10 MeV using the electron accelerator facility at RRCAT, Indore. Pre and post- irradiation measurements of the electrical characteristics are undertaken to investigate the electron induced device degradation and damage. The dominant mechanism of the interaction of the electrons with semiconductors is to produce atomic displacement which can have serious impact on electrical characteristics. MOS (Metal oxide semiconductor) devices are the most sensitive of all semiconductor devices to radiation showing considerable degradation even for a relatively low dose of exposure to high energy electrons. The energy dissipated by electrons in semiconductors is sufficient to displace silicon atoms and causes a shift in the threshold voltage and leakage current. The study indicates that the gate threshold voltage substantially decreases with the increase in electron dose. The leakage current increases with dose which could have an impact on the performance of the device. The transconductance of the MOS transistor is found to decrease with increase in electron dose. The observed changes in the electrical characteristics upon electron irradiation are analysed and interpreted as due to trapped charges in the SiO2 layer and at the interface. The present investigation reveals that there is a remarkable degradation in threshold voltage and the leakage current displays substantial increase when the devices are exposed to electrons. This increase in leakage current can have significant impact on device performance in a radiation environment.

Comparing post-deposition and post-metallization annealing treatments on Al2O3/GaN capacitors for different metal gates

Vertical Metal–Insulator–Semiconductor (MIS) capacitors with an Al2O3 thin film as a gate insulator have been fabricated on homoepitaxial GaN-on-GaN samples. The effect of the annealing treatments on the MIS characteristics has been investigated exploring two different approaches: Post-insulator-Deposition-Annealing (PDA) and Post-gate-Metallization-Annealing (PMA), i.e., annealing on the bare Al2O3 layer and annealing after the gate metallization deposition on Al2O3. The direct comparison between PDA and PMA is crucial to understand the impact of the metal/dielectric interface quality on the behavior of the Al2O3/GaN MIS capacitors. The efficacy of annealing has been monitored as a function of metal gates having different work functions: nickel (Ni), molybdenum (Mo), and tantalum (Ta). It has been found that both PDA and PMA approaches are equally able to improve the Al2O3/GaN interface electrical quality. However, the PMA demonstrates an additional beneficial effect on the metal/Al2O3 interface. In particular, the possible chemical reactions activated by the annealing process at the metal/dielectric interface can perturb the known metal/dielectric dipole responsible for Fermi-level pinning phenomena, causing a positive shift of the flat voltage (VFB), which depends on the metal, and approaching the theoretical value in the case of Mo and Ta.

Recovery of drain-induced threshold voltage shift by positive gate bias in GaN power HEMTs with p-GaN gate

We demonstrate that exposure to positive gate bias can favor a fast recovery of the threshold voltage variation induced by off-state stress, in p-GaN gate high electron mobility transistors. Two process splits were investigated, having different Schottky barriers at the metal/p-GaN junction. Results indicate that: (a) drain stress may result in significant threshold voltage increase; (b) devices with sufficiently high gate leakage current show an immediate recovery after gate turn-on, resulting in stable operation in actual applications. The contribution of leakage current is demonstrated, based on recovery experiments at different voltages and for the same rate of hole injection from the gate.

A Novel Isolation Approach for GaN-Based Power Integrated Devices.

This paper introduces a novel technology for the monolithic integration of GaN-based vertical and lateral devices. This approach is groundbreaking as it facilitates the drive of high-power GaN vertical switching devices through lateral GaN HEMTs with minimal losses and enhanced stability. A significant challenge in this technology is ensuring electrical isolation between the two types of devices. We propose a new isolation method designed to prevent any degradation of the lateral transistor's performance. Specifically, high voltage applied to the drain of the vertical GaN power FinFET can adversely affect the lateral GaN HEMT's performance, leading to a shift in the threshold voltage and potentially compromising device stability and driver performance. To address this issue, we introduce a highly doped n+ GaN layer positioned between the epitaxial layers of the two devices. This approach is validated using the TCAD-Sentaurus simulator, demonstrating that the n+ GaN layer effectively blocks the vertical electric field and prevents any depletion or enhancement of the 2D electron gas (2DEG) in the lateral GaN HEMT. To our knowledge, this represents the first publication of such an innovative isolation strategy between vertical and lateral GaN devices.

Amorphous InZnSnO thin-film-transistors performance enhancement with low-energy Xenon Pulsed-light annealing

The electrical characteristics and stability of amorphous indium-zinc-tin oxide (IZTO) thin-film transistors (TFTs) were significantly improved in this study using low-energy Xenon pulsed-light annealing (PLA). In comparison to conventional furnace annealing (FA), PLA treatment significantly reduced the processing temperature and annealing time. Besides, the defect states are obviously reduced from 1.73×1012 cm-2 to 6.53×1011 cm-2 by PLA treatment, resulting in improved device electrical characteristics and enhanced reliability, including improved carrier mobility from 20.08 to 39.61 cm2/V∙s, threshold voltage from 0.82 to 0.24 V, subthreshold swing (S.S.) from 0.54 to 0.24 V/decade, and the ON/OFF current ratio from 2.32×107 to 7.31×108. In addition, the enhanced stability is observed under both positive gate-bias stress (PGBS) of VGS = 30 V and negative gate-bias stress (NGBS) of VGS = –30 V for a stress duration of 3000 s. The threshold voltage shift (ΔVTH) is reduced from 8.31 V to 1.65 V and from –3.93 V to –1.51 V, respectively. This is the first time low-energy PLA was conducted for IZTO TFT performance improvement.

Plasma-enhanced atomic layer deposition of indium-free ZnSnOx thin films for thin-film transistors

An appropriate synthesis technique for growing high-quality indium-free ZnSnOx (ZTO) films should be developed to achieve high-performance thin-film transistors (TFTs) utilizing ZTO films. This study investigated the growth characteristics and electrical properties of ZTO thin films grown via plasma-enhanced atomic layer deposition (PEALD) using bis(1-dimethylamino-2-methyl-2-propoxide)Sn, diethylzinc, and O2 plasma to optimize the composition and enhance the device performance. Deviations were observed in the growth per cycle when using PEALD for ZTO, compared with binary oxides. In the PEALD of the ZTO films, the introduction of the SnO2 sub-cycle enhanced the mass gain in the ZnO sub-cycle, whereas the mass gain in the SnO2 sub-cycle decreased with the addition of the ZnO sub-cycle. This was attributed to changes in the density of the functional groups on the reaction surface. Precise control over the composition was achieved, enabling the identification of the optimal Zn58Sn42Ox composition. Post-deposition annealing significantly improved the TFT performance, with devices showing enhanced mobility, positive shifts in the threshold voltage, and reduced subthreshold swing values. These improvements stemmed from reductions in oxygen vacancies and sub-gap defect states. These findings highlight the potential of PEALD-grown ZTO films for use in high-performance, cost-effective TFTs, facilitating their integration into modern semiconductor electronics.

Back-side stress to ease p-MOSFET degradation on e-MRAM chips

Abstract The magnetoresistive random access memory process makes a great contribution to threshold voltage deterioration of metal–oxide–silicon field-effect transistors, especially on p-type devices. Herein, a method was proposed to reduce the threshold voltage degradation by utilizing back-side stress. Through the deposition of tensile material on the back side, positive charges generated by silicon–hydrogen bond breakage were inhibited, resulting in a potential reduction in threshold voltage shift by up to 20%. In addition, it was found that the method could only relieve silicon–hydrogen bond breakage physically, thus failing to provide a complete cure. However, it holds significant potential for applications where additional thermal budget is undesired. Furthermore, it was also concluded that the method used in this work is irreversible, with its effect sustained to the chip package phase, and it ensures competitive reliability of the resulting magnetic tunnel junction devices.

Increased Static Charge‐Induced Threshold Voltage Shifts and Memristor Activity in Pentacene OFETs Comprising Polystyrene‐Based Gate Dielectrics Containing Electroactive Small Molecule Crystallites

AbstractTop‐contact bottom‐gate pentacene OFETs are fabricated with single layer dielectrics comprised of either polystyrene (PS), poly(4‐methylstyrene) (P4MS), or poly(4‐tert‐butylstyrene) (P4TBS). The polystyrenes are blended with varying concentrations of two different small molecules, dibenzotetrathiafulvalene (DBTTF) and 2,8‐difluoro‐5,11‐bis(triethylsilylethynyl)anthradithiophene (diF‐TES‐ADT), to form small, separated crystallites contained throughout the polymer dielectric layer. The OFET characteristics of these devices are investigated and their threshold voltage shifts are measured after −70 V static charging for 5 min. Two‐terminal measurements are conducted using multiple different gate biases in the range of −50 to +50 V to investigate memristor behavior in the devices. OFETs containing DBTTF exhibited ΔVth increases as large as 330% relative to control OFETs containing no DBTTF, while OFETs containing at least 7.5 wt.% DBTTF exhibited memristor activity, with currents ranging from 20 nA to 44 µA depending on the applied bias. This work demonstrates that including small, separated crystallites in polymer dielectrics enhances their charge storage ability and can be promising for creating nonbinary memory devices for data processing. Additionally, the observed memristor activity indicates the OFETs in this work can be used in development of neuromorphic systems that aim to mimic the synaptic behavior of the human nervous system.