Thermal power cycles using sCO2 as a working fluid place extreme demands on their turbomachinery components and their electric motors/generators. In this paper, new system topologies for sCO2 turbomachinery are proposed which take advantage of “bearingless” electric machine technology to improve performance. Bearingless motors/generators are a new type of electric machine which integrate the functionality of active magnetic bearings into the existing hardware of an electric motor/generator. The existing electromagnetic surfaces and materials are reused to enable controllable production of radial forces on the machine shaft. This is envisioned to improve hermetic direct-drive turbomachinery systems by either augmenting existing bearings (i.e., bearing assist) or replacing existing bearings (i.e., bearing removal). The state-of-the-art technologies for several bearing types (gas foil bearings, externally pressurized porous (EPP) gas bearings, and active magnetic bearings) and electric machines are reviewed to motivate the introduction of bearingless technology. Two system designs using bearingless machines are proposed and compared against existing commercial solutions in terms of maximum shaft weight, number of passthroughs into the hermetic environment, cost, and complexity. A case-study bearingless motor/generator is assessed via simulations and a hardware prototype to investigate practical considerations for using bearingless technology in sCO2 turbomachinery. The proposed bearingless solutions have potential to enable a new generation of sCO2 turbomachinery with improved reliability, reduced complexity, and lower cost. This paper shows that by transforming the motor/generator already present in turbomachinery into a bearingless motor/generator, the technical challenges involved with sCO2 can be overcome without adding significant cost.