This study aims to determine the relationship on the application of Genius Hour in teaching 21st Century Literature from the Philippines and the World and students learning achievement. Accordingly, this study gathered data from the respondents from the three (3) sections of Science, Technology, Mathematics, and Engineering (STEM) Grade 11 at Laguna State Polytechnic University Santa Cruz Senior High School Department (LSPU-SCC SHS Department), rendering a total of 110 responses. The main instruments used in this research were the self-madae questionnaire and the self-made rubrics. The data gathered using these instruments were statistically treated through Mean, Standard Deviation, Frequency, and Pearson R. This set of information were gathered through the application of Genius Hour, and the responses of the students were taken using the Google Form. Additionally, the researcher utilized the self-made rubric in order to determine students learning achievement. Based on the data analyzed, it was revealed that the students have a Very High level of application of their risk assessment, strengths and weaknesses, planning of approach, application of strategies, and reflection in relation to the application of Genius Hour in teaching Literature and Media under the subject 21st Century Literature from the Philippines and the World. Moreover, it also showed that the students also have Very High level of engagement with risk assessment, strengths and weaknesses, planning of approach, application of strategies, and reflection in relation to the application of Genius Hour in teaching in the same topic of the said subject. Further, the study also revealed that as per indicator Over-all Quality of Presentation, students learning achievement was Satisfactory, and as per indicators Effort, Inquisitiveness, Originality of Idea, and Over-all Learning, students learning achievement were proven Excellent. Based on the findings and conclusions drawn from this study, the researcher would like to recommend the following: 1) The teachers may consider the use of Genius Hour in teaching, not only on the subject 21st Century Literature in the Philippines and the World, but also on different subjects considering that Genius Hour is a student-centered teaching pedagogy, and 21st century classrooms are also learner-centered 2) The teachers and future researchers, considering that this study was conducted only using the online distance learning, may consider adapting the strategies to an in-person classroom setting 3) Stakeholders may consider the results of the study on their planning given that the students application of and engagement on Genius Hour both have significance on their learning achievements 4) Students may refer on this study in order for them to understand their need to wonder, ask questions, be inquisitive, and create their own research is vital for their learning and their future as an individual. This may also help them realize that their competencies are harnessed by different approaches their teachers apply in their class 5) Future researchers, contrary to how the researcher gathered information on the students application, may conduct in-person classes and gather data on the level of students application based on the teachers assessment and not on the learners perception 6) Future researchers may also utilize the variables that were used considering that all indicators and predictors were proven to provide a satisfying outcome for this study, specifically Application of Strategies, as it was proven to be very strongly significant in students learning achievement and, 7) Future researchers may use this study as it may serve as data bank for further enrichment of their readings of similar nature and thus may strengthen further the findings of the present research undertaking.