With the rapid development of the Belt and Road Initiative, the cultivate of interdisciplinary language talents should be further explored. As the International Language Service has became a subdiscipline under the Discipline of Foreign Language and Literature, the cultivation and training of contemporary language service talents has began to accelerate. This paper discussed overall development of language service industry, the challenges, principles, macro strategy and micro approaches of cultivating qualified language service talents to meet the requirements for the Belt and Road Initiative. This paper addresses the importance of strategy and planning of the subject of language service, and the necessity to hand over the rights to set sub-discipline to teaching units. Specific approaches includes but not limited to disciplinary integration from the begin to the end of course framework, integration of discipline and technology, integration of various entities involved in the cultivation, such as government, industry and enterprises, universities and research institutes.