Electrode Materials For Sensors Research Articles

Photocatalytic degradation of direct green & fast orange red dyes: Electrochemical sensor of lead using cupric oxide nanoparticles synthesized via sonochemical route

In this study, nanocrystalline cupric oxide was produced using a basic, low-cost sonochemical method (CuO). Through powder X-ray diffraction, the phase and nanocrystalline nature of CuO nanoparticles (NPs) were determined. The Kubelka-Monk function revealed that the band gap of CuO in diffuse reflectance spectra (DRS) is 1.75 ​eV. Ingenious photocatalysts for the removal of the dyes Direct green (DG) and Fast orange red (F-OR) have been demonstrated to work with CuO NPs. To examine the photocatalytic characteristics of NPs under UV light and sunlight irradiation, Direct Green (DG) and Fast Orange Red (F-OR) dyes were utilised as traditional dyes. Direct green dye was found to be excited at 624.1 and 623.8 ​nm in UV and sunlight, while Fast orange red dye is excited at 496.8 and 495.1 ​nm. Lead in 0.1 ​N HCl solution was detected using the cyclic voltammetry (CV) method with a modified carbon paste electrode (MCPE). According to electrochemical performance, CuO is an advantageous sensing electrode material for an element like lead.

Enzyme Free Detection of Glucose Using MgO Nanocubes Based Extended Gate N-channel MOSFET

MgO nanocubes were used as a sensing electrode material for detection of glucose in the extended gate field effect transistor (EGFET) configuration. MgO nanocubes were prepared by thermal CVD approach. Morphology and elemental composition of as-prepared MgO nanocubes were obtained using the scanning electron microscope (SEM) along with EDS. The sensing electrode was prepared by coating MgO nanocubes over the copper foil by doctor blade method and it was tested with various concentrations of glucose in Phosphate Buffer Saline (PBS) buffer solution. The MgO nanocubes coated electrode showed linear response for glucose concentrations from 1.6 mM to 25.6 mM. The sensitivity was calculated as 0.12 |aA/mM.cm2.

In Situ Wet Synthesis of N-ZnO/N-rGO Nanohybrids as an Electrode Material for High-Performance Supercapacitors and Simultaneous Nonenzymatic Electrochemical Sensing of Ascorbic Acid, Dopamine, and Uric Acid at Their Interface

The present manuscript reports one-pot greener in situ synthesis of nanohybrids (N-GZO320) consisting of nitrogen-doped ZnO (N-ZO) particles (with an average size of 16 nm) coated on nitrogen-doped...

Machine Learning-Assisted Development of Sensitive Electrode Materials for Mixed Potential-Type NO2 Gas Sensors.

Yttrium-stabilized zirconia (YSZ)-based mixed potential-type NOx sensors have broad application prospects in automotive exhaust gas detection. Great efforts continue to be made in developing high-performance sensitive electrode materials for mixed potential-type NO2 gas sensors. However, only five kinds of new sensing electrode materials have been developed for this type of gas sensor in the last 3 years. In this work, four different tree-based machine learning models were trained to find potentially sensitive electrode materials for NO2 detection. More than 400 materials were selected from 8000 materials by the above machine learning models. To further verify the reliability of the model, 13 of these materials containing unexploited elements were selected as sensitive electrode materials for making sensors and testing their gas-sensing performances. The experimental results showed that all 13 materials exhibited good gas-sensing performance for NO2. More interestingly, an electrode material BPO4, which does not contain any metal elements, was also screened out and showed good sensing properties to NO2. In a short period of time, 13 new sensitive electrode materials for NO2 detection were targeted and screened, which was difficult to achieve by a trial-and-error procedure.

Mixed-potential ammonia sensor using Ag decorated FeVO4 sensing electrode for automobile in-situ exhaust environment monitoring

High-performance YSZ-based mixed potential NH3 sensor has been developed and utilized with the prospect of excellent applications in in-vehicle SCR (Selective Catalytic Reduction) systems. In order to further lower the detection limit and improve the sensitivity to NH3, we prepared Ag decorated FeVO4 as sensing electrode material through the NaBH4 reduction method in this work. Electrochemical methods such as cyclic voltammetry (CV), linear sweep voltammetry (LSV) and I-t curves are used to explore and compare the electrochemical catalytic activity of electrode materials. 3 mol% Ag decorated FeVO4 was considered as the best sensing electrode material because of its highest electrochemical catalytic activity and reliable stability. Also, the reaction product under the sensor’s working condition was confirmed by the online mass spectrometer. The sensor attached with 3 mol% Ag decorated FeVO4-SE could give a response of − 57 mV to 50 ppm NH3 in 3s and recover to base line in 16s, exhibiting its rapid detection ability at high temperature of 550 °C. Moreover, it displayed good selectivity and a low detection limit of 200 ppb. Additionally, the stability of the sensor under different oxygen concentration and humidity was studied in detail.

Ce0.8Gd0.2O1.95-based mixed potential type triethylamine sensor utilizing La2NiFeO6 sensing electrode

Mixed potential Ce0.8Gd0.2O1.95-based gas sensors utilizing double perovskite type composite oxide La2NiFeO6 – prepared by sol-gel method and sintered at different temperatures – as sensing electrode were fabricated to detect triethylamine (TEA). The influence of the sensing electrode materials with different sintering temperatures on sensing properties of the sensors was mainly studied. Results showed that the sensor utilizing La2NiFeO6 sintered at 1100 °C had the highest response value (−123.2 mV) towards 50 ppm TEA at 490 °C. The greater sensitivity of the sensor was explained by the fact that La2NiFeO6 sintered at 1100 °C had bigger electrochemical active area compared with the other two materials (La2NiFeO6 sintered at 1100 °C/1200 °C), which was confirmed by testing the electric double-layer capacitance (EDLC) of the materials. Besides, the response value of the sensor displayed a linear relationship with the logarithm of TEA concentration, and the slope was −62.2 mV/decade at the range of 0.5–200 ppm TEA. It also displayed good repeatability and selectivity. The fabricated TEA sensor would have good application prospects in the fields spanning from biomedical, chemical detection to seafood safety control.

An electrochemical dopamine sensor based on RF magnetron sputtered TiO2/SS thin film electrode

Titanium Dioxide (TiO2) coated Stainless Steel (SS) thin film (TiO2/SS) as electrochemical Dopamine (DA) sensing electrode materials are synthesized via a Radio Frequency Magnetron Sputtering (RFMS) method. TiO2 nanomaterial is uniformly dispersed on the surface of SS, thus enhancing the electronic conductivity and preventing the aggregation of TiO2/SS thin film. The TiO2/SS thin film exhibit good efficiency which is 0.0219 ± 0.01 µA/µM for the linear range of 50 µM – 450 µM with a detection limit of 23 nM.

YSZ-Based Mixed Potential Type NH3 Sensor Attached with Ag Doped FeVO4 Sensing Electrode

Introduction In an automobile selective catalytic reduction (SCR) system, the monitoring of NH3 concentration is of vital importance. NH3 detection in such harsh environment of high temperature and humidity is an almost impossible task for most testing methods. Nevertheless, YSZ-based mixed potential type gas sensor is an incomparable choice. Moreover, the development and utilization of sensing electrode materials is an effective method to develop high performance YSZ-based mixed potential type ammonia gas sensor [1]. FeVO4, a n-type semiconductor with direct band gap, is considered as a promising sensing electrode material due to its special three-dimensional layered structure [2]. Ag was reported to have excellent catalytic activity. Through Ag collaborating with the sensing electrode, the response of the NH3 sensor could be enhanced accompanied by the improved sensitivity and detection limit [3]. In this study, we prepared FeVO4 through the sol-gel method. Then, Ag doped FeVO4 in different molar ratio (1.5, 2.5, 3.5 and 4.5 mol.%) was synthesized through the sodium borohydride reduce method and used as sensing electrode material of the YSZ-based mixed potential type NH3 gas sensor. The effects of different molar ratios Ag doped on the NH3 sensing performance were studied. The sensor attached with 3.5 mol.% Ag doped FeVO4 displays high response to target NH3 gas, short response and recovery time, satisfying humidity resistance and good repeatability, indicating its potential for in-situ ammonia monitoring for automotive applications [4]. Method Fabrication and measurement of the gas sensor The sensor was fabricated on a YSZ plate (8 mol. % Y2O3 doped, 2 mm × 2mmsquare, 0.2 mm thickness), provided by Anpeisheng Corp. China. A point-shaped electrode and a narrow stripe-shaped electrode were formed on the two sides using a commercial Pt paste (Sino-platinum Metals Co. Ltd.), and sintered at 1000°C. The sensing material was mixed with a minimum quantity of deionized water and the resultant paste was applied on the point-shaped Pt to form stripe-shaped SE and then sintered at 800 °C for 2 h. The testing method of the sensor was as showed in our previous work [5]. Results and Conclusions A series of sensing tests showed the sensor attached with 3.5 mol.% Ag doped FeVO4-SE had the highest response to NH3, as Fig.1a shows. The reason that the sensor attached with 3.5 mol.% Ag doped FeVO4-SE have the highest sensing performance is due to best electrochemical catalytic activity to NH3 of the sensing electrode materials. The best electrochemical catalytic activity of the material will be proved by the polarization curves and complex impedance test in the future. The NH3 sensing performance of the sensor attached with 3.5 mol.% Ag doped FeVO4 was studied at different operating temperatures and the optimal operating temperature was determined at 550 °C, as Fig.1b shows. The sensor could even detect as low as 200 ppb NH3 with the response of -3.2 mV, as shown in Fig.1 c. Also, the sensor had a good reproducibility as shown in Fig.1 d. Moreover, the sensor displayed good selectivity to NH3 when compared to other interfering gases such as NO2, SO2, C2H2 and CO, as shown in Fig.1 e. For accurate and rapid detection of NH3, the response and recovery time is a vital indicator. In the present research, the typical 90% response time to 50 ppm NH3 of the sensor was less than 3 s as shown in Fig.1 f. In the actual working condition, the exhaust gas is always of high humidity. Therefore, the environmental humidity’s influence on the NH3 sensor was studied and the result in F ig.1g and h showed that the sensor had an acceptable humidity stability. Based on the above results, the sensor we fabricated is prospective in automobile selective catalytic reduction (SCR) exhaust gas treatment system.

A trace ppb-level electrochemical H2S sensor based on ultrathin Pt nanotubes

An amperometric sensor has been developed with high sensitivity for real-time measurement of H2S gas at room temperature (25 °C ± 2 °C). In order to enhance the utilization of platinum and improve its catalytic performance, an ultrathin and one-dimensional (1D) Pt nanotubes (Pt NTs, ~3.5 nm in wall thickness) were designed and used as sensing electrode materials. Different concentrations of H2S gas were tested to evaluate the sensitivity of the sensor and to obtain the relationship between the electricity response signal and H2S gas concentration. At room temperature, the sensor based on Pt NTs shows better sensing performance than that based on Pt nanoparticles, which is mainly attributed to two factors, namely, the inherent characteristic of the hollow 1D Pt NTs. The Pt NTs-based sensor shows a detection limit as low as 0.025 ppb, which are the lowest among H2S gas sensors reported in the literatures. The response and recovery times are 0.75 s and 0.86 s for 0.8 ppb H2S, respectively. In addition, the sensor shows a wide range (100 ppm-0.025 ppb), high selectivity compared to other gases (including CO, NH3, CH2O, NO and NO2), good reproducibility, and satisfactory long-term stability. Thus, the ultrathin Pt NTs-based gas sensor would be a great potential to the real-time and online monitoring of the trace ppb-level H2S gas at room temperature.

Mixed potential type NH3 sensor based on YSZ solid electrolyte and metal oxides (NiO, SnO2, WO3) modified FeVO4 sensing electrodes

YSZ-based mixed potential type NH3 sensor has a good application foreground in on-board SCR (Selective Catalytic Reduction) system due to its good thermal and chemical stability. In this study, we greatly improved the NH3 sensing performance of this type of sensor to meet the detection requirement through the development of high-performance sensing electrode materials. FeVO4 was synthesized through a traditional sol-gel method and used as basis material. In order to improve the electrochemical catalytic activity, different molar ratio of metal oxides (NiO, SnO2, WO3) modified FeVO4 were prepared. The cyclic voltammetry (CV), the linear sweep voltammetry (LSV) and dc polarization (I–V) measurements were carried out to confirm the electrochemical catalytic activity of the sensing electrode materials. Eventually, the sensor attached with 20 mol.% NiO modified FeVO4-SE exhibited the highest response (−83 mV) to 100 ppm NH3 and had a low detection limit of 5 ppm. What is more, the sensor also displayed short response and recovery time, satisfying oxygen resistance and good stability over 20 days at 650 °C, indicating its potential for in-situ ammonia monitoring in industrial and automotive applications.

PH Sensitivity Estimation in Potentiometric Metal Oxide pH Sensors Using the Principle of Invariance

A numerically solvable engineering model has been proposed that predicts the sensitivity of metal oxide- (MOX-) based potentiometric pH sensors. The proposed model takes into account the microstructure and crystalline structure of the MOX material. The predicted pH sensitivities are consistent with experimental results with the difference below 6% across three MOX (RuO2, TiO2, and Ta2O5) analysed. The model distinguishes the performance of different MOX phases by the appropriate choice of surface hydroxyl site densities and dielectric constants, making it possible to estimate the performance of MOX electrodes fabricated through different high-temperature and low-temperature annealing methods. It further addresses the problem, cited by theoreticians, of independently determining the C1 inner Helmholtz capacitance parameter while applying the triple-layer model to pH sensors. This is done by varying the C1 capacitance parameter until an invariant pH sensitivity across different electrolyte ionic strengths is obtained. This invariance point identifies the C1 capacitance. The corresponding pH sensitivity is the characteristic sensitivity of MOX. The model has been applied across different types of metal oxides, namely, expensive platinum group oxides (RuO2) and cheaper nonplatinum group MOX (TiO2 and Ta2O5). High temperature annealed, RuO2 produced a high pH sensitivity of 59.1082 mV/pH, while TiO2 and Ta2O5 produced sub-Nernstian sensitivities of 30.0011 and 34.6144 mV/pH, respectively. Low temperature annealed, TiO2 and Ta2O5 produced Nernstian sensitivities of 59.1050 and 59.1081 mV/pH, respectively, illustrating the potential of using cheaper nonplatinum group MOx as alternative sensor electrode materials. Separately, the usefulness of relatively less investigated, cheap, and readily available MOX, viz. Al2O3, as the electrode material was analysed. Low-temperature-annealed Al2O3 with a Nernstian sensitivity of 59.1050 mV/pH can be considered as a potential electrode material. The proposed engineering model can be used as a preliminary prediction mechanism for choosing potentially cheaper alternative sensor electrode materials.

2D Accordion‐like MXene Nanosheets as a Sensitive Electrode Material for Baicalin Sensing

AbstractHerein, accordion‐like MXene nanosheets was used as electrode sensing material for baicalin determination in traditional Chinese medicine preparation for the first time. The consecutive multilayer nanostructure of MXene observably enhanced the electroactive surface area of electrode and accelerated the electron transfer rate to acquire outstanding electrochemical response to baicalin. The electrode process of baicalin and relative dynamic parameters were investigated using cyclic voltammetry and chronocoulometry. Under optimized conditions, a good linear relationship was achieved between the response current and baicalin levels over the range of 0.08–60 μM with a detection limit of 26 nM (S/N=3). The developed sensor was successfully applied for baicalin monitoring in traditional Chinese medicine preparation and human urine samples.

A Nanocomposite Containing Carbon Nano‐onions and Polyaniline Nanotubes as a Novel Electrode Material for Electrochemical Sensing of Daidzein

AbstractGlassy carbon electrode (GCE) were modified with nanocomposites containing conductive polyaniline nanotubes (PANInt) and carbon nano‐onions (CNOs). Herein we report a simple and sensitive way for daidzein (DA) determination at concentrations between 1 and 10 μM by linear sweep voltammetry using GCE/PANInt/CNOs system. The DA electrochemical behavior was examined in two buffer environments (pH 7.5 and 4.5) using electrodes modified with the oxidized CNOs or their derivatives containing carboxyl and benzylamino functional groups. The direct electrooxidation of DA was observed at +0.65 V and +0.8 V at pH 7.5 and at +0.7 V and +1.1 V vs. Ag/AgCl at pH 4.5.

Mesoporous titanium niobium nitrides supported Pt nanoparticles for highly selective and sensitive formaldehyde sensing

A highly sensitive and selective formaldehyde sensor is prepared by using mesoporous Ti0.75Nb0.25N supported Pt NPs as a high efficiency gas sensing electrode material.

Design of an enzyme-mimicking NiO@Au nanocomposite for the sensitive electrochemical detection of lactic acid in human serum and urine

Detection of lactic acid (LA) in biological systems is required for medical diagnostics and the management of numerous medical conditions due to its key active metabolic role in the production of glycogen in muscle. Herein, we report on the facile synthesis of a novel enzyme-free gold (Au) modified flower-structured nickel oxide (NiO@Au) nanocomposite through an electrochemical strategy, which resulted in the generation of a sensing electrode material with robust synergistic effects. This sensing platform contained highly porous structured NiO flowers, which provided an extensive surface area with the capacity to mimic enzymatic activity, akin to lactate dehydrogenase (LDH) and lactate oxidase (LOD), etc. for the oxidation of LA. The effective dispersion of Au on NiO further enhanced the electron transfer process at the electrode surface. The developed sensor demonstrated a low detection limit of 11.6 µM, high sensitivity of 8.0 µA/mM, a wide linear range between 100.0 µM and 0.5 M, exceptional selectivity against potential interferences such as cystamine, ascorbic acid, uric acid, and glucose, and excellent stability over repeated cycles. The developed sensor was further tested for the detection and determination of LA in human serum and urine samples, showing that this new NiO@Au nanocomposite has strong practical applicability. The present study established a novel strategy for the synthesis of a unique NiO@Au nanocomposite, while offering a powerful and reliable electrochemical platform for the sensitive detection of LA, which translates to broad applications in biomedical, food safety, and environmental monitoring.

Specificity improvement of the YSZ-based mixed potential gas sensor for acetone and hydrogen sulfide detection

In this paper, mixed potential gas sensor using yttria-stabilized zirconia (YSZ) solid electrolyte was developed for acetone and hydrogen sulfide detection. By adjusting the operating temperature and fabricating a double-sensing electrode gas sensor, the specificity of the device was effectively improved. At first, we successfully synthesized two kinds of sensing electrode materials NiAlGaO4 and Sm1.2Sr0.8CoO4 by sol-gel method. The sensor based on NiAlGaO4 sensing electrode and Pt reference electrode performed high sensing performances to both acetone and hydrogen sulfide (H2S). By controlling the operating temperature of the sensor, we successfully improved the specificity of the device to H2S against acetone at 700 °C. However, when measuring acetone, H2S was still a non-negligible influential factor. Hence, sensing electrode material Sm1.2Sr0.8CoO4 was used to replace Pt electrode and develop a double-sensing electrode gas sensor. Due to the similar sensing property to H2S and the difference to acetone between NiAlGaO4 and Sm1.2Sr0.8CoO4, the double-sensing electrode sensor performed a good specificity to acetone against H2S. The response of the double-sensing electrode sensor to 10 ppm acetone was 15 mV while approximated 0–10 ppm H2S. The low detection limit of the present device could reach 1 ppm and the sensitivity of the sensor was 21 mV/decade. The result of simulation exhaled breath measurement exhibits the sensors we fabricated have an enormous potential for non-invasive breath analysis.

(Invited) Peptide Screening for the Regulation of Gold Nano-Biomineralization Using Peptide Array Technology

Some peptides have been utilized in the functionalization of nanomaterials, the control of nanoparticle (NP) synthesis, as biotemplating for morphological control, and biocatalysts for the NP crystallization. The catalytic peptides used for NP synthesis, named biomineralisation peptides, generally demonstrate high specific binding to a target material, and are screened from a peptide library (e.g. phage display library). However, the properties of NPs synthesized, using such biomineralization peptides, cannot be predicted from screening process; thus the development of a rational peptide screening method which can be used to synthesize NPs with specific morphological and optical properties would greatly expand the potential of biomineralization peptides.Herein, we focused on gold, which is also used as an electrode material for sensors, and developed an efficient method for identifying peptides that bind to gold nanoparticles (AuNPs). Using the spot synthesis-based peptide array technique, AuNP binding activities of approximately 1,800 peptides were firstly evaluated and revealed various activities ranging from positive (high-affinity binding peptides) to negative (weak- or null-affinity binding peptides). Among 50 peptides showing the highest AuNP binding activity, 46 sequences showed the presence of tryptophan-based motifs including W[Xn]W, H[Xn]W, and W[Xn]H (W: tryptophan, X: any amino acid, n: 1 to 8 amino acid residues), whereas none of these motifs was found in the WORST50 peptides. Notably, by using peptide array comprising high-binding peptides, more than 100 sequences were discovered at once to have AuNP synthetic ability on the peptide array. In addition, the image analysis of peptide array disclosed the optical property information from synthesized AuNPs at each peptide spot. Subsequently, screened peptides were demonstrated as suitable agents for the one-pot aqueous-phase synthesis of AuNPs and optical properties shown in the solution were consistent with that of array. Furthermore, obtained AuNPs were characterized to three types regarding to their optical properties, which are red, green and blue. The particle sizes were around 8.9, 2.6 and 34.7 nm respectively. These techniques are show potential not only in improved AuNP biomineralizations, but also could be used in the synthesis of other inorganic nanomaterials, such as semiconductor and magnetic particles in ambient condition. In this talk, I will also present some research examples using peptide array technology for biosensor development. References Tanaka, M., et al., (2017) Acta Biomaterialia, 49, 495-506.Tanaka, M., et al., (2019) Nanoscale Adv., 1, 71-75.Tanaka, M., et al., (2020) Int. J. Mol. Sci., 21(7), 2377Komikawa, T., et al., (2020) Biosens. Bioelectron., 153, p112030 Figure 1

Flexible Waterproof Piezoresistive Pressure Sensors with Wide Linear Working Range Based on Conductive Fabrics

HighlightsThe laser-engraved method was introduced to fabricate the electrode for the sensor.The sensor showed a wide linear working range, superior sensitivity, and fast response time and also exhibited excellent viability in a wet situation.Wireless integrated network sensors successfully monitored the health states.Developing flexible sensors with high working performance holds intense interest for diverse applications in leveraging the Internet-of-things (IoT) infrastructures. For flexible piezoresistive sensors, traditionally most efforts are focused on tailoring the sensing materials to enhance the contact resistance variation for improving the sensitivity and working range, and it, however, remains challenging to simultaneously achieve flexible sensor with a linear working range over a high-pressure region (> 100 kPa) and keep a reliable sensitivity. Herein, we devised a laser-engraved silver-coated fabric as “soft” sensor electrode material to markedly advance the flexible sensor’s linear working range to a level of 800 kPa with a high sensitivity of 6.4 kPa−1 yet a fast response time of only 4 ms as well as long-time durability, which was rarely reported before. The integrated sensor successfully routed the wireless signal of pulse rate to the portable smartphone, further demonstrating its potential as a reliable electronic. Along with the rationally building the electrode instead of merely focusing on sensing materials capable of significantly improving the sensor’s performance, we expect that this design concept and sensor system could potentially pave the way for developing more advanced wearable electronics in the future.

Large scale preparation of polyaniline/polyvinyl alcohol hybrid films through in-situ chemical polymerization for flexible electrode materials

Flexible electrode materials are inevitable for high-end applications such as wearable electronics, implantable microelectrodes, artificial muscles, various sensors, and biomedical devices. A simple and easy method for large scale preparation of mechanically stable and flexible electrode material using PANI and PVA films is presented. The hybrid films prepared through the chemical coating of PVA using an in-situ chemical polymerization of aniline were highly electroactive and comprised of coral-like nanowires of PANI grown on the surface of PVA films resulting large surface area and high porosity as evinced from SEM studies. FTIR spectra showed characteristic bands of PANI and PVA. Bandgap energies estimated were consistent with the electrical conductivity of the films. The doubly coated film showed an electrical conductivity as high as 4.0 × 10−2 S cm−1. The high electrochemical activity studied through cyclic voltammetry was attributed to the easy diffusion of ions through the porous nanowires of PANI on the surface of the films. Thermal studies revealed that hybrid films are thermally more stable. The tensile strength of the hybrid films was comparable with that of pure PVA film in the dry state while in the wet state the single coated film was mechanically more stable. Sorption studies showed that the mass swelling ratio of the hybrid films was decreased due to the incorporation of PANI into the hydrogel matrix. As the films were mechanically stable and highly electroactive and can be cut into pieces of any desirable size and shape we propose that they can be used as active electrode materials for sensors, supercapacitors, actuators, etc.

Electrochemical assay of ampicillin using Fe3N-Co2N nanoarray coated with molecularly imprinted polymer.

Self-supported Fe3N-Co2N nanoarray with high electric conductivity and large surface area was prepared for growth of MIPs and further constructing a sensitive and stable electrochemical sensor. For the evaluation of its performance, Fe3N-Co2N is used as sensing electrode material, and AMP is used as template molecule to construct the MIP electrochemical sensor. Under the optimized conditions, the developed MIPs electrochemical sensor detects AMP with a low detection limit of 3.65 × 10-10molL-1 and shows outstanding reproducibility and stability. When the MIPs electrochemical sensor was applied to detect AMP in milk samples via standard addition method, the recovery within 97.06-102.43% with RSD of 1.05-2.11% was obtained. The fabrication of MIPs electrochemical sensor is highly promising for sensitive and selective electrochemical measurement and food safety testing. This work can provide theoretical guidance for truly challenging problems. Graphical abstract Principle diagram of MIP-EC sensor for detecting AMP Molecular imprinted polymers (MIPs) are widely performed for construction of electrochemical (EC) sensors especially for detecting small molecules in complex environment. However, the large-scale and robust preparation of MIPs in situ on sensor platform limits their practical applications. We fabricated a MIPs EC sensor based on Fe3N-Co2N in situ grown on carbon cloth (CC) as the substrate platform (Fe3N-Co2N/CC) combining with MIPs as the target recognition element for the label-free detection of AMP. Under the optimal conditions, the developed MIPs EC sensor can detect AMP with a low detection limit of 3.65 × 10-10molL-1. When the AMP in milk is detected by the proposed EC sensor, it shows ideal results. Therefore, the use of self-supported Fe3N-Co2N nanoarray as the platform for the fabrication of MIPs EC sensors is highly promising for sensitive and selective EC measurement and point-of-care testing.