Breast milk is a great supply of vitamins for newborns, breast milk contains a variety of iron needed for growth and for the development of the baby. This study was conducted at the Puskesmas of East Baturaja District, OKU Regency. This study used quantitative research. The sample in this study were 32 breastfeeding mothers. This observe used a move sectional technique and this observe used gear withinside the shape of the Pittsburgh Sleep Quality Index (PSQI) questionnaire, the Perceived Stress Scale (PSS) questionnaire, and the Fluency of Breast Milk Questionnaire. From the results of statistical tests it was found that mothers who experienced good sleep quality were 19 respondents (67,9%) even as the easy manufacturing of breast milk changed into pretty easy as many as 8 respondents (28,6%). Based on bivariate evaluation of Chi-Square take a look at effects acquired p-value 0,004 (<0,05). Even as from the consequences of statistical checks of moms who've moderate strain tiers as many as 14 respondents (73,7%) even as the clean manufacturing of breast milk is pretty clean eight respondents (28,6%). Based on bivariate evaluation of Chi-Square take a look at consequences acquired p-value 0,001 (<0,05). From the conclusion of this study, there is a significant relationship between sleep quality, stress level, and milk production in breastfeeding mothers at the Puskesmas of East Baturaja District, OKU Regency.