The purpose of the work was to study the effect of targeted physical therapy in scoliotic disease on changes in carbohydrate metabolism in patients with metabolic syndrome. The dependence of visceral fat and glycated hemoglobin levels on the C-shaped right-sided thoracic scoliosis as stimulated through comprehensive physical therapy is being investigated. A hypodynamic lifestyle and a forced posture when sitting during working hours causes a change in the spinal rotation which deform the thorax and affect functioning of the organs. Materials and Methods: the study involved 36 patients split into two groups. The level of glycated hemoglobin was higher than 5.93% in women and 6.05% in men. The same physical and diet therapy was prescribed for the two groups. However, the main study group combined targeted exercises and kinesio-taping to reduce the scoliosis. Results: based on the distribution of χ2 the classical method of processing statistical data was applied to the study, which is well applicable for a small amount of data. The statistical data showed a linear dependence between the Cobb angle and glycosylated hemoglobin level which was especially pronounced in women prior to physical therapy. The correlation between glycosylated hemoglobin level and the Cobb angle declined in both men and women with an improvement in posture. Conclusions: with a decrease in the Cobb angle, the correlation between it and the level of glycosylated hemoglobin decreased in both men and women, which confirms the hypothesis that carbohydrate metabolism is associated with changes in the pancreas that occur due to rotational changes in the spine. By studying metabolic syndrome, even in small groups of patients, general practitioners will be able to expand the list of treatment recommendations.