This study aimed to design the application of science during the Covid-19 pandemic in elementary school. This study used the literature review method which was divided into two types of references, primary references (8 references) and secondary references (supporting journal articles). References were sourced from google scholar, tandfonline, and observations in the surrounding environment. Data analysis was carried out in stages, starting from collecting data, analyzing, and drawing conclusions. The results of this study provide a design for the application of science in elementary schools during the Covid-19 pandemic, by implementing good communication between students, teachers, and parents, and the need for appropriate media to help students understand learning topics. Besides, through the design of the application of science to learning, it can overcome learning problems by implementing the Covid-19 Health protocol.