Rotational Stimuli Research Articles

Interplay of photonic, electrical, and inertial loads on the stability of rotating sector perovskite sandwich plates with a GPL-based nanocomposite core

The bifurcation stability of sandwich sector plates, primarily constructed from lead halide perovskite skins known for their significant photostrictive and electrostrictive properties, is explored. These properties render them highly relevant for multiphysics applications. The influence of a photo-induced thermal environment on the behavior of these plates is also examined. A notable challenge, the inherent stiffness of these structures, is addressed by integrating a nanocomposite laminated core composed of a polymer matrix and graphene platelet (GPL) reinforcers. The GPLs are distributed throughout the core layers according to functionally graded models, significantly enhancing structural integrity. To effectively model the core environment, the Halpin-Tsai micromechanical rule is employed. The structural displacement field is modeled using the first-order shear deformation theory. Moreover, the von-Kármán geometrically nonlinear strain-displacement relations are applied. The constitutive relationships are governed by the theory of linear photo-thermo-electro-elasticity, providing a framework for the analysis of perovskite-based structures. The reorganization of bifurcation points from the pre-buckling route and the linearization of stability equations are performed using the adjacent-equilibrium criterion. The generalized differential quadrature (GDQ) method is utilized to solve the equilibrium equations of pre-buckling and the stability equations of buckling. This comprehensive investigation reveals the critical influence of photonic, electrical, and rotational stimuli on the stability characteristics of advanced perovskite-based sandwich sector plates, demonstrating potential advancements in multiphysics applications.

2D4-5 The Influence of Musical Tempo on VR Motion Sickness Induced by Visual Rotational Stimuli

2D4-5 The Influence of Musical Tempo on VR Motion Sickness Induced by Visual Rotational Stimuli

Designing a Motion-Onset Visual-Evoked Potential-Based Brain–Computer Interface to Control a Computer Game

Brain-computer interface (BCI) establishes an alternative direct communication channel between the brain and computer or other external devices. Motion-onset visual evoked potential (mVEP) related to the individual perception of movement is among synchronous BCI system that utilizes external stimulus. mVEPs stimulation paradigm is like an oddball stimulation paradigm. Researchers have recently been investigating mVEPs to control a computer game. To control a computer game, they used translation stimulus to evoke these potentials in EEG brain signals. In this study, we examine designing a computer game with four different types of stimuli, including translation, contraction, expansion, and rotation. We also used time-domain and wavelet coefficients for the feature extraction. Also, we used different types of linear discriminant analysis (LDA) classification methods, including least absolute shrinkage and selection operator (LASSO), stepwise LDA (SWLDA); moreover, and spatial-temporal discriminant analysis (STDA) for detecting the target stimulus. Our results demonstrate that contraction, expansion, and rotation stimuli, as well as translation, could be employed to control a BCI game. Our results showed that subjects got higher scores, game accuracy control, and information transfer rate using the rotation stimulus with SWLDA/STDA classification methods.

Atrial Natriuretic Peptide Alleviates Motion Sickness Potentially through Regulating Endolymph Volume in the Inner Ear Increased by Arginine Vasopressin

Introduction: Dimenhydrinate and scopolamine are frequently used drugs, but they cause drowsiness and performance decrement. Therefore, it is crucial to find peripheral targets and develop new drugs without central side effects. This study aimed to investigate the anti-motion sickness action and inner ear-related mechanisms of atrial natriuretic peptide (ANP). Methods: Endolymph volume in the inner ear was measured with magnetic resonance imaging and expression of AQP2 and p-AQP2 was detected with Western blot analysis and immunofluorescence method. Results: Both rotational stimulus and intraperitoneal arginine vasopressin (AVP) injection induced conditioned taste aversion (CTA) to 0.15% sodium saccharin solution and an increase in the endolymph volume of the inner ear. However, intraperitoneal injection of ANP effectively alleviated the CTA behaviour and reduced the increase in the endolymph volume after rotational stimulus. Intratympanic injection of ANP also inhibited rotational stimulus-induced CTA behaviour, but anantin peptide, an inhibitor of ANP receptor A (NPR-A), blocked this inhibitory effect of ANP. Both rotational stimulus and intraperitoneal AVP injection increased the expression of AQP2 and p-AQP2 in the inner ear of rats, but these increases were blunted by ANP injection. In in vitro experiments, ANP addition decreased AVP-induced increases in the expression and phosphorylation of AQP2 in cultured endolymphatic sac epithelial cells. Conclusion: Therefore, the present study suggests that ANP could alleviate motion sickness through regulating endolymph volume of the inner ear increased by AVP, and this action of ANP is potentially mediated by activating NPR-A and antagonising the increasing effect of AVP on AQP2 expression and phosphorylation.

Embodied mental rotation ability in open- and closed-skill sports: pilot study with a new virtual paradigm

Embodied mental rotation is the influence of the body on mental rotation ability. Sports expertise enhances embodied mental rotation ability. However, sport-skill-dependent effects remain unclear. Previous studies refer to the influence of body positions on mental rotation ability. Yet, in sports, the investigation of the effect of simultaneous body and mental rotation movements is essential. Athletes need to constantly mentally and physically adapt to environmental changes and new motor tasks while being in motion themselves. This study aimed to investigate embodied mental rotation ability with simultaneous body and mental rotation in individuals with different sport skills, i.e., in open- and closed-skill sports. Forty-eight men and women, divided into two groups depending on their sport, performed 32 trials of an extended embodied mental rotation task. Simultaneous body and mental rotation were enabled by a novel test method including Virtual Reality. Results revealed shorter response times to the task stimulus in closed-skill sports participants than in open-skill sports participants. This group difference was significant for trials in which rotation directions of the own body and the mental rotation stimulus were aligned. The results might be related to sport-specific skill development processes. Motor imitation skills, as relevant in many closed-skill sports, may facilitate cognitive processes when the motion direction of the own body and of the mental rotation stimulus are aligned. The novel test method identifies potential applications that should be increasingly explored in the future, both for cognitive science and sports research.

Dynamic alpha power modulations and slow negative potentials track natural shifts of spatio-temporal attention.

Alpha power modulations and slow negative potentials have previously been associated with anticipatory processes in spatial and temporal top-down attention. In typical experimental designs, however, neural responses triggered by transient stimulus onsets can interfere with attention-driven activity patterns and our interpretation of such. Here, we investigated these signatures of spatio-temporal attention in a dynamic paradigm free from potentially confounding stimulus-driven activity using electroencephalography. Participants attended the cued side of a bilateral stimulus rotation and mentally counted how often one of two remembered sample orientations (i.e., the target) was displayed while ignoring the uncued side and non-target orientation. Afterwards, participants performed a delayed match-to-sample task, in which they indicated if the orientation of a probe stimulus matched the corresponding sample orientation (previously target or non-target). We observed dynamic alpha power reductions and slow negative waves around task-relevant points in space and time (i.e., onset of the target orientation in the cued hemifield) over posterior electrodes contralateral to the locus of attention. In contrast to static alpha power lateralization, these dynamic signatures correlated with subsequent memory performance (primarily detriments for matching probes of the non-target orientation), suggesting a preferential allocation of attention to task-relevant locations and time points at the expense of reduced resources and impaired performance for information outside the current focus of attention. Our findings suggest that humans can naturally and dynamically focus their attention at relevant points in space and time and that such spatio-temporal attention shifts can be reflected by dynamic alpha power modulations and slow negative potentials.

How embodied is cognition? fMRI and behavioral evidence for common neural resources underlying motor planning and mental rotation of bodily stimuli.

Functional neuroimaging shows that dorsal frontoparietal regions exhibit conjoint activity during various motor and cognitive tasks. However, it is unclear whether these regions serve several, computationally independent functions, or underlie a motor "core process" that is reused to serve higher-order functions. We hypothesized that mental rotation capacity relies on a phylogenetically older motor process that is rooted within these areas. This hypothesis entails that neural and cognitive resources recruited during motor planning predict performance in seemingly unrelated mental rotation tasks. To test this hypothesis, we first identified brain regions associated with motor planning by measuring functional activations to internally-triggered vs externally-triggered finger presses in 30 healthy participants. Internally-triggered finger presses yielded significant activations in parietal, premotor, and occipitotemporal regions. We then asked participants to perform two mental rotation tasks outside the scanner, consisting of hands or letters as stimuli. Parietal and premotor activations were significant predictors of individual reaction times when mental rotation involved hands. We found no association between motor planning and performance in mental rotation of letters. Our results indicate that neural resources in parietal and premotor cortex recruited during motor planning also contribute to mental rotation of bodily stimuli, suggesting a common core component underlying both capacities.

Quantitative analysis and correlative evaluation of video-oculography, micro-computed tomography, and histopathology in Pendrin-null mice

Patients with SLC26A4 mutations exhibit highly variable hearing loss and vestibular dysfunction. Although Slc26a4 mutant mice similarly exhibit vestibular deficits, including circling behavior, head tilting, and torticollis, the underlying pathogenesis of the vestibular symptoms remains unclear, hindering its effective management for patients with SLC26A4 mutations. In this study, we evaluated the equilibrium function using the inspection equipment, which can record eye movements against rotational, gravitational, and thermal stimulations. Moreover, we correlated the degree of functional impairment with the morphological alterations observed in Slc26a4Δ/Δ mice. The rotational stimulus and ice water caloric tests revealed considerable impairment of the semicircular canal, while the tilted gravitational stimulus test showed a severe functional decline of the otolithic system in Slc26a4Δ/Δ mice. Generally, the degree of impairment was more severe in circling Slc26a4Δ/Δ mice than in non-circling Slc26a4Δ/Δ mice. In non-circling Slc26a4Δ/Δ mice, the semicircular canal function was normal. Micro-computed tomography results showed enlargement of the vestibular aqueduct and bony semicircular canals but no correlative relationship between the severity of the caloric response and the size of bony labyrinths. Giant otoconia and a significant decrease in total otolith volume in the saccule and utricle were observed in Slc26a4Δ/Δ mice. However, the giant otoconia were not overly dislocated in the bony otolithic system and ectopic otoconia were absent in the semicircular canal. The number and morphology of the utricular hair cells in Slc26a4Δ/Δ mice were not significantly reduced compared to those in Slc26a4Δ/+ mice. Collectively, we can conclude that vestibular impairments are mainly associated with otoconia formation and morphology rather than hair cell degeneration. In addition, severe disturbances of semicircular canals cause circling behavior in Slc26a4Δ/Δ mice. Our comprehensive morphological and functional assessments apply to mouse models of other genetic diseases with vestibular impairment.

Evaluation of effects of optokinetic and rotational stimuli with functional head impulse test (fHIT) in individuals with motion sickness.

To evaluate effects of optokinetic and rotational stimulus in individuals with and without motion sickness (MS) using fHIT. The study included subjects aged 18-40; 35 subjects with MS for MS group and 35 subjects without vertigo for control group. Percentage of the correct answer (% CA) with and without optokinetic stimulus (o-fHIT) in the frontal plane in the fHIT test was compared in both groups. In addition, both group subjects were seated on an ordinary rotating office chair. % CA was compared between groups by applying rotational fHIT (r-fHIT) test after the subjects were rotated randomly to the right and left and also simultaneously moved their heads in the vertical plane. There was no significant difference in % CA in fHIT o-fHIT and r-fHIT in the control group. Both groups showed a significant difference in % CA for fHIT, o-fHIT, and r-fHIT for all SCCs (p < 0.05). Since individuals with MS are affected by optokinetic and rotational stimuli, fHIT performed after these stimuli can be used as an objective confirming test for diagnosing MS.

Comparing the impact of the method of adjustment and forced-choice methodologies on subjective visual vertical bias and variability.

Previous research suggested that the method of adjustment and forced choice variants of the subjective visual vertical (SVV) produce comparable estimates of both bias and variability. However, variants of the SVV that utilize a method of adjustment procedure are known to be heavily influenced by task parameters, including the stimulus rotation speed, which was not accounted for in previous SVV research comparing the method of adjustment to forced-choice. The aim of the present study was to determine if (1) the SVV with a forced-choice procedure produces both bias and variability estimates that are comparable to those obtained using a method of adjustment procedure, (2) to see if rotation speed impacts the comparability of estimates and (3) quantify correlations between the estimates produced by different procedures. Participants completed a variant of the SVV which utilized a forced-choice procedure as well as two variants of the SVV using a method of adjustment procedure with two different rotation speeds (6°/s and 12°/s). We found that the bias estimates were similar across all three conditions tested and that the variability estimates were greater in the SVV variants that utilized a method of adjustment procedure. This difference was more pronounced when the rotation speed was slower (6°/s). The results of this study suggest that forced-choice and method of adjustment methodologies yield similar bias estimates and different variability estimates. Given these results, we recommend utilizing forced-choice procedures unless (a) forced-choice is not feasible or (b) response variability is unimportant. We also recommend that clinicians consider the SVV methods when interpreting a patient's test results, especially for variability metrics.

Event-related potentials during mental rotation of body-related stimuli in spinal cord injury population

Mental rotations of body-related stimuli are known to engage the motor system and activate body schema. Sensorimotor deficits following spinal cord injury (SCI) alter the representation of the body with a negative impact on the performance during motor-related tasks, such as mental rotation of body parts. Here we investigated the relationship between event-related potentials in SCI participants and the difficulty in mentally rotating a body-part. Participants with SCI and healthy control subjects performed a laterality judgment task, in which left or right images of hands, feet or animals (as a control stimulus) were presented in two different orientation angles (75° and 150°), and participants reported the laterality of the stimulus. We found that reaction times of participants with SCI were slower for the rotation of body-related stimuli compared to non-body-related stimuli and healthy controls. At the brain level, we found that relative to healthy controls SCI participants show: 1) reduced amplitudes of the posterior P100 and anterior N100 and larger amplitudes of the anterior P200 for overall stimuli; 2) an absence of the modulation of the rotation related negativity by stimulus type and rotation angles. Our results show that body representation changes after SCI affecting both components of early stimulus processing and late components that process high-order cognitive aspects of body-representation and task complexity.

Effects of Aging, Sex and Forgetfulness on Mental Rotation Performance

AbstractBackgroundThere is growing interest in the development of screening tests for AD and MCI that focus on non‐amnestic symptoms. Moreover, evidence suggests that declining mental rotation ability can be associated with prodromal Alzheimer’s Disease (AD) and Mild Cognitive Impairment (MCI). Additional studies in healthy aging adults are therefore needed to determine whether computerized mental rotation tasks may prove useful in predicting cognitive decline.MethodHere, we report findings from a large group of aging adults (n = 276, 42% female, aged 56–89 years, M = 70.5) who were remotely administered a computerized mental rotation task as part of a larger California Cognitive Assessment Battery (CCAB). During the mental rotation task, participants had to decide as quickly as possible whether a presented letter was in its typical (e.g., R) versus mirror‐reversed (Я) orientation. Letters were presented either upright (at 0 degrees) or rotated (+/‐60, or +/‐120 degrees). Participants’ responses on the Cognitive Failures Questionnaire were also collected as part of the assessment battery.ResultResponse times (RT) and accuracy on the mental rotation task were captured and analyzed to determine whether any effects of age, sex, and rotation angle could be observed using this remotely administered mental rotation task. Analysis revealed that both age and sex were significantly associated with performance measures on this task. The expected pattern of longer response times with greater degree of stimulus rotation was also observed. Analysis of sex differences revealed greater accuracy overall by females, while males experienced smaller RT costs based on rotation angle. Finally, a significant relationship between forgetting scores and mental rotation response times was also observed.ConclusionIncreased age and forgetting scores were both associated with worse mental rotation performance. Continuing longitudinal assessment at 6‐month intervals is ongoing and will further establish trends in mental rotation performance during aging.

Mental Rotation in Sports

Abstract: This study further validates the sport-specific Mental Rotation Test – Basketball (MRT-BB) in which participants solve 24 items regarding basketball plays. The task of each item consists of comparing four alternative stimuli with a criterion stimulus and identifying the two “correct” alternatives. A total of 203 participants (101 females) took part in this experiment in which they solved the original MRT and the MRT-BB. The results replicate the findings of Weigelt and Memmert (2021 ). The number of items attempted declined toward the end of each set, with participants solving more items in the second set and men outperforming women. While participants solved more items on the MRT-BB, performance in both tests was positively correlated. Our replication of the previous results supports the validity of the MRT-BB. The correlation supports the notion that the mental rotation of the sport-specific stimuli is based on more general mental rotation skills.

Representational Processes of Actions Toward and Away from the Body.

The aim of the present study was to investigate the role of mental representation processes during the planning, reaching, and use phases of actions with tools commonly used toward the body (TB, e.g., toothbrush) or away from the body (AB, e.g., pencil). In the first session, healthy participants were asked to perform TB (i.e., making circular movements with the toothbrush near the mouth) and AB (i.e., making circular movements with the pencil near the desk) actions both with (i.e., actual use) and without the tool in hand (i.e., the pantomime of tool use). In the second session, the same participants performed a series of mental rotation tasks involving body- (i.e., face and hands) and object-related (i.e., abstract lines) stimuli. The temporal and kinematic analysis of the motor actions showed that the time required to start the pantomimes (i.e., the planning phase) was shorter for the AB action than for the TB action. In contrast, the reaching phase lasted longer for the AB action than for the TB action. Furthermore, the TB pantomime was associated with the performance in the mental rotation of body-related stimuli, especially during the planning and reaching phases, whereas the AB pantomime was more related to the performance in the mental rotation of object-related stimuli, especially during the tool use phase. Thus, the results revealed that the direction of a goal-directed motor action influences the dynamics of the different phases of the motor action and can determine the type of mental images involved in the planning and execution of the action.

Effector-dependent stochastic reference frame transformations alter decision-making.

Psychophysical, motor control, and modeling studies have revealed that sensorimotor reference frame transformations (RFTs) add variability to transformed signals. For perceptual decision-making, this phenomenon could decrease the fidelity of a decision signal's representation or alternatively improve its processing through stochastic facilitation. We investigated these two hypotheses under various sensorimotor RFT constraints. Participants performed a time-limited, forced-choice motion discrimination task under eight combinations of head roll and/or stimulus rotation while responding either with a saccade or button press. This paradigm, together with the use of a decision model, allowed us to parameterize and correlate perceptual decision behavior with eye-, head-, and shoulder-centered sensory and motor reference frames. Misalignments between sensory and motor reference frames produced systematic changes in reaction time and response accuracy. For some conditions, these changes were consistent with a degradation of motion evidence commensurate with a decrease in stimulus strength in our model framework. Differences in participant performance were explained by a continuum of eye–head–shoulder representations of accumulated motion evidence, with an eye-centered bias during saccades and a shoulder-centered bias during button presses. In addition, we observed evidence for stochastic facilitation during head-rolled conditions (i.e., head roll resulted in faster, more accurate decisions in oblique motion for a given stimulus–response misalignment). We show that perceptual decision-making and stochastic RFTs are inseparable within the present context. We show that by simply rolling one's head, perceptual decision-making is altered in a way that is predicted by stochastic RFTs.

Impact of walking speed and motion adaptation on optokinetic nystagmus-like head movements in the blowfly Calliphora

The optokinetic nystagmus is a gaze-stabilizing mechanism reducing motion blur by rapid eye rotations against the direction of visual motion, followed by slower syndirectional eye movements minimizing retinal slip speed. Flies control their gaze through head turns controlled by neck motor neurons receiving input directly, or via descending neurons, from well-characterized directional-selective interneurons sensitive to visual wide-field motion. Locomotion increases the gain and speed sensitivity of these interneurons, while visual motion adaptation in walking animals has the opposite effects. To find out whether flies perform an optokinetic nystagmus, and how it may be affected by locomotion and visual motion adaptation, we recorded head movements of blowflies on a trackball stimulated by progressive and rotational visual motion. Flies flexibly responded to rotational stimuli with optokinetic nystagmus-like head movements, independent of their locomotor state. The temporal frequency tuning of these movements, though matching that of the upstream directional-selective interneurons, was only mildly modulated by walking speed or visual motion adaptation. Our results suggest flies flexibly control their gaze to compensate for rotational wide-field motion by a mechanism similar to an optokinetic nystagmus. Surprisingly, the mechanism is less state-dependent than the response properties of directional-selective interneurons providing input to the neck motor system.

On-board reagent storage and release by solvent-selective, rotationally opened membranes: a digital twin approach

Decentralized bioanalytical testing in resource-poor settings ranks among the most common applications of microfluidic systems. The high operational autonomy in such point-of-care/point-of-use scenarios requires long-term onboard storage of liquid reagents, which also need to be safely contained during transport and handling, and then reliably released just prior to their introduction to an assay protocol. Over the recent decades, centrifugal microfluidic technologies have demonstrated the capability of integrated, automated and parallelized sample preparation and detection of bioanalytical protocols. This paper presents a novel technique for onboard storage of liquid reagents which can be issued by a rotational stimulus of the system-innate spindle motor, while still aligning with the conceptual simplicity of such “Lab-on-a-Disc” (LoaD) systems. In this work, this highly configurable reagent storage technology is captured by a digital twin, which permits complex performance analysis and algorithmic design optimization according to objectives as expressed by target metrics.

Recognition of rotated objects and cognitive offloading in dogs

SummaryRecognition of rotated images can challenge visual systems. Humans often diminish the load of cognitive tasks employing bodily actions (cognitive offloading). To investigate these phenomena from a comparative perspective, we trained eight dogs (Canis familiaris) to discriminate between bidimensional shapes. We then tested the dogs with rotated versions of the same shapes, while measuring their accuracy and head tilts. Although generalization to rotated stimuli challenged dogs (overall accuracy: 55%), three dogs performed differently from chance level with rotated stimuli. The amplitude of stimulus rotation did not influence dogs’ performance. Interestingly, dogs tilted their head following the direction and amplitude of rotated stimuli. These small head movements did not influence their performance. Hence, we show that dogs might be capable of recognizing rotated 2D objects, but they do not use a cognitive offloading strategy in this task. This work paves the way to further investigation of cognitive offloading in non-human species.

Normative data for ages 18-45 for ocular motor and vestibular testing using eye tracking.

ObjectiveEye tracking technology has been employed in assessing ocular motor and vestibular function following vestibular and neurologic conditions, including traumatic brain injury (TBI). Assessments include tests that provide visual and motion (rotation) stimuli while recording horizontal, vertical, and torsional eye movements. While some of these tests have shown diagnostic promise in previous studies, their use in clinical practice is limited by the lack of normative data. The goal of this study was to construct normative reference ranges to be used when comparing patients' results.MethodsOptokinetic response, subjective visual horizontal and vertical, and rotation tests were administered to male and female volunteers, ages 18‐45, who were free from neurological, vestibular disorders, or other head injuries. Tests were administered using either a rotatory chair or a portable virtual reality‐like goggle equipped with video‐oculography.ResultsReference values for eye movements in response to different patterns of stimuli were analyzed from 290 to 449 participants. Analysis of gender (self‐reported) or age when grouped as pediatric (late adolescent; 18‐21 years of age) and adult (21‐45 years of age) revealed no effects on the test metrics. Data were pooled and presented for each test metric as the 95% reference interval (RI) with 90% confidence intervals (CI) on upper and lower limits of the RI. ConclusionsThis normative database can serve as a tool to aid in diagnosis, treatment, and/or rehabilitation protocols for vestibular and neurological conditions, including mild TBI (mTBI). This database has been cleared by the FDA for use in clinical practice (K192186).Level of evidence2b

Modulation of Vestibular Microphonics: A Historical Note.

Modulation of microphonics has recently been used to investigate the sensitivity of the utricle in the vestibular organ of the guinea pig. The same technique was used more than 30 years ago to obtain information on the processing of rotational stimuli in the horizontal semicircular canals of the pigeon. Data from that time were reanalysed to give a relation that describes the mechano-electrical transduction (MET) process in vestibular hair cells.