In recent years, prefabricated structures have been widely constructed to reduce construction costs and time. In this study, a new type of prefabricated structure, lightweight concrete-filled steel tubular (CFST)-framed building assembled with microcrystalline foam boards (MFBs), was developed. The MFBs exhibited high strength, heat insulation, soundproof, light weight, fireproof, and ecofriendly characteristics. The MFBs were combined with light steel keels and connected to the CFST frame with flexible and rigid connections. Shaking table tests on a full-scale, two-story, single-span lightweight CFST-framed building assembled with MFBs as exterior wallboards were performed to assess its dynamic properties and seismic response under the earthquake. The input waves used for the shaking table tests were the El-Centro, Taft, and Zhangjiakou artificial waves with seismic ground motion intensities of 8°–9°. The results indicated that the CFST-framed building exhibited satisfactory seismic performance. The main damage behavior was the cracking and spalling of the MFBs, however, the MFBs used as exterior wallboards were easy to repair and replace. No wallboard collapse occurred, and the lightweight CFST frame was in the elastic deformation stage. The flexible connections absorbed a large amount of energy, resulting in a reduction in the displacement of the structure and little damage to the wallboards under the earthquake. Finally, a nonlinear distribution model of acceleration amplification factors for calculating the seismic force on MFBs was established.
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