Objective To investigate the clinical effect of zirconia all-ceramic crown for anterior teeth restoration, and its influence on the quality of life. Methods Eighty-four patients with anterior teeth repair[4 cases were lost during the follow-up, and there were 80 cases (106 teeth)] were selected.According to different surgical methods, they were divided into control group(56 teeth) and study group(50 teeth). The control group used Ni Cr alloy porcelain crown, the study group used two zirconia all-ceramic crown.The patients were followed up for 1 year, the repair effect, incidence rate of adverse reactions and quality of life score were compared between the two groups. Results After 1 year of crown restoration, the color, integrity, edge coloring in the study group were significantly better than those in the control group(all P 0.05). The quality of life scores in the study group after repair were significantly higher than those in the control group(t=18.623, 22.389, 20.724, 10.190, all P<0.05). Conclusion The clinical effect of zirconia all-ceramic crown for anterior teeth restoration is better.It can improve the aesthetic effect, safety and quality of life score of patients.It is worthy of popularizing and application in clinic. Key words: Tooth preparation, prosthodontic; Metal ceramic alloys; Dental alloys; Quality of life