The purpose of this work is to improve veterinary and hygienic methods for implementing the reproductive qualities of sows and preserving the health of suckling piglets. The animals of the 1st experimental group were injected intramuscularly with the immunotropic preparation PigStim-C at a dose of 5 ml per head three times 10 and 5 days before weaning from piglets and directly during weaning. The Pigstim-M immunotropic preparation was injected into the sows of the 2nd experimental group at the specified time and at the same dose. The animals of the control group were not injected with immunotropic drugs and other procedures not provided for by the technological map were not performed. It was found that intramuscular injection of PigStim series immunotropic drugs (PIGSTIM-C and PigStim-M) to sows 10 and 5 days before and immediately after weaning of piglets contributed to: the earliest manifestation of signs of hunting and a reduction in the period from weaning to insemination; an increase to 100% of the fruitfulness of insemination; a reduction in the duration of farrowing by 1.0-1.1 hours and the optimal course of the birth and postpartum periods by reducing the number of sows in need of obstetric care, and the number of postpartum diseases, such as metritis-mastitis-agalactia syndrome; an increase in the multiple pregnancy of sows by 1.0 – 1.2 heads, a decrease in the number of stillbirths and an increase in the number of piglets received from the group as a whole by 22 and 24 heads; an increase in the safety of piglets during the suckling period by 1.78 and 0.32% and an increase in the number of piglets weaned from sows by an average of 1.2 heads and in the group as a whole by 24 heads.