This paper presented a method to estimate the pressure relief time of spacecraft cabin by testing a single component in the airway. Comparison between the theoretical prediction and experimental measurement indicates that there exits two methods which can effectively predict the pressure relief time of spacecrafts: measuring the effective flow area each single component or direct measurement of the effective flow area of the pressure relief system composed of single component. It also should be noted that the latter one can bring about a smaller error. Therefore, when conditions were met, the measurement and calculation of the system composed of components could more accurately predict the time required for the spacecraft pressure to drop to the target point.