As more and more people shift their purchasing habits from bricks-and-mortar stores to online platforms, e-commerce practitioners must understand the factors that influence consumers’ purchase intentions. By identifying these key determinants, practitioners can develop effective strategies to attract and retain customers. This study aims to examine the impact of information quality, product quality, user satisfaction, system quality, and service quality on consumers’ purchase intentions in e-commerce. Empirical data were collected from 181 consumers to capture their perceptions of e-commerce, the factors influencing their purchase intentions, and the relationships between them. The data were then analyzed using Pearson’s correlations and structural equation modelling techniques to determine the importance of each factor. The results show that information quality, product quality, user satisfaction, system quality, and service quality significantly influence consumers’ purchase intentions in e-commerce. This study provides valuable insights into the factors that affect consumers’ purchase intentions in e-commerce and allows practitioners to develop appropriate strategies customized to their own context.