Promising Types Research Articles

Polymorph of LiAlP2O7: Combined Computational, Synthetic, Crystallographic, and Ionic Conductivity Study.

We report a new polymorph of lithium aluminum pyrophosphate, LiAlP2O7, discovered through a computationally guided synthetic exploration of the Li-Mg-Al-P-O phase field. The new polymorph formed at 973 K, and the crystal structure, solved by single-crystal X-ray diffraction, adopts the orthorhombic space group Cmcm with a = 5.1140(9) Å, b = 8.2042(13) Å, c = 11.565(3) Å, and V = 485.22(17) Å3. It has a three-dimensional framework structure that is different from that found in other LiMIIIP2O7 materials. It transforms to the known monoclinic form (space group P21) above ∼1023 K. Density functional theory (DFT) calculations show that the new polymorph is the most stable low-temperature structure for this composition among the seven known structure types in the AIMIIIP2O7 (A = alkali metal) families. Although the bulk Li-ion conductivity is low, as determined from alternating-current impedance spectroscopy and variable-temperature static 7Li NMR spectra, a detailed analysis of the topologies of all seven structure types through bond-valence-sum mapping suggests a potential avenue for enhancing the conductivity. The new polymorph exhibits long (>4 Å) Li-Li distances, no Li vacancies, and an absence of Li pathways in the c direction, features that could contribute to the observed low Li-ion conductivity. In contrast, we found favorable Li-site topologies that could support long-range Li migration for two structure types with modest DFT total energies relative to the new polymorph. These promising structure types could possibly be accessed from innovative doping of the new polymorph.

Advances in Photocrosslinkable Materials for 3D Bioprinting

3D bioprinting integrating multidisciplinary advances in engineering, cell biology, and material science is able to fabricate artificial tissues and organ‐like structures with biology or clinic‐relevant size, shape, and structural integrity. Therefore, 3D bioprinting has huge potential in tissue engineering and regenerative medicine. Suitable bioink plays a key role in the modulation of the printing process, the properties, and functions of printed constructs. Herein, the advances in photocrosslinkable biomaterials are focused on, which have been proven as promising types of bioinks for 3D bioprinting. The general strategies of 3D bioprinting and the main mechanisms involved in photocrosslinking are first discussed. Then, the recent advances in photocrosslinkable bioinks including natural protein‐ and polysaccharide‐based materials, synthetic polymers, and decellularized extracellular matrix (dECM)‐based materials are highlighted. Finally, the ongoing challenges in the delicate balance between the printability and biological activities of photocrosslinkable biomaterials are discussed and the outlook for this emerging area is analyzed.

Giant room temperature elastocaloric effect in metal-free thin-film perovskites

Solid-state refrigeration which is environmentally benign has attracted considerable attention. Mechanocaloric (mC) materials, in which the phase transitions can be induced by mechanical stresses, represent one of the most promising types of solid-state caloric materials. Herein, we have developed a thermodynamic phenomenological model and predicted extraordinarily large elastocaloric (eC) strengths for the (111)-oriented metal-free perovskite ferroelectric [MDABCO](NH4)I3 thin-films. The predicted room temperature isothermal eC ΔSeC/Δσ (eC entropy change under unit stress change) and adiabatic eC ΔTeC/Δσ (eC temperature change under unit stress change) for [MDABCO](NH4)I3 are −60.0 J K−1 kg−1 GPa−1 and 17.9 K GPa−1, respectively, which are 20 times higher than the traditional ferroelectric oxides such as BaTiO3 thin films. We have also demonstrated that the eC performance can be improved by reducing the Young’s modulus or enhancing the thermal expansion coefficient (which could be realized through chemical doping, etc.). We expect these discoveries to spur further interest in the potential applications of metal-free organic ferroelectrics materials towards next-generation eC refrigeration devices.

Фактор транскрипции 7 (TCF7L2): фактор риска развития сахарного диабета 2 типа

The genetics of Type 2 diabetes a complex metabolic disorder, characterized by decreased insulin secretion and insulin resistance resulting in impaired blood glucose homeostasis remains enigma for geneticists. In 2006 an important step while finding genetic causes of diabetes type 2 was identification of transcription factor 7-like 2 (TCF7L2) gene an important marker in predisposition of type 2 diabetes in almost all ethnic population. Recent genetic research identifies numerous novel type 2 diabetes susceptible genes among these genes TCF7L2 is considered as gang head and emerged as the most promising types 2 diabetes causing gene. Risk variants in TCF7L2 effects pancreatic beta cell development and insulin secretion by influencing Wnt Signaling pathway. Genetic variants in TCF7L2 confer risk for type 2 diabetes by altering expression of transcription factor (which has key role in blood glucose regulation) in pancreas. The purpose of this paper is to evaluate type 2 diabetes susceptible gene the TCF7L2 and to present a comprehensive review of studies carried out worldwide in different ethnic population on association of TCF7L2 polymorphism with type 2 diabetes.

Adipose-derived stem cells alleviate radiation-induced dermatitis by suppressing apoptosis and downregulating cathepsin F expression

BackgroundRadiation-induced dermatitis is a serious side effect of radiotherapy, and very few effective treatments are currently available for this condition. We previously demonstrated that apoptosis is an important feature of radiation-induced dermatitis and adipose-derived stem cells (ADSCs) are one of the most promising types of stem cells that have a protective effect on acute radiation-induced dermatitis. Cathepsin F (CTSF) is a recently discovered protein that plays an important role in apoptosis. In this study, we investigated whether ADSCs affect chronic radiation-induced dermatitis, and the underlying mechanisms involved.MethodsADSCs were isolated from male Sprague-Dawley (SD) rats and characterized. For in vivo studies, rats were randomly divided into control and ADSC-treated groups, and cultured ADSCs were transplanted into radiation-induced dermatitis model rats. The effects of ADSC transplantation were determined by skin damage scoring, histopathological analysis, electron microscopy, immunohistochemical staining, and western blotting analysis of apoptosis-related proteins. To evaluate the effects of ADSCs in vitro, radiation-induced apoptotic cells were treated with ADSC culture supernatant, and apoptosis-related protein expression was investigated by TUNEL staining, flow cytometry, and western blotting.ResultsIn the in vivo studies, skin damage, inflammation, fibrosis, and apoptosis were reduced and hair follicle and sebaceous gland regeneration were enhanced in the ADSC group compared with the control group. Further, CTSF and downstream pro-apoptotic proteins (Bid, BAX, and caspase 9) were downregulated, while anti-apoptotic proteins (Bcl-2 and Bcl-XL) were upregulated. In vitro, ADSCs markedly attenuated radiation-induced apoptosis, downregulated CTSF and downstream pro-apoptotic proteins, and upregulated anti-apoptotic proteins.ConclusionADSCs protect against radiation-induced dermatitis by exerting an anti-apoptotic effect through inhibition of CTSF expression. ADSCs may be a good therapeutic candidate to prevent the development of radiation-induced dermatitis.

Помологические особенности форм айвы, обнаруженных на территории Нахичевани

The article examines the areas of spread of quince types found in the territory of the Nakhchivan, their names and synonyms and which sortotype they belong to. For the first time, 11 types of quinces were found in the territory of Nakhchivan, and agro-biological traits were studied by conducting phenological observations on them. The development of annual shoots and fruits of each type was monitored separately, promising types were selected, and grafted material was taken from them, grafted in the area where they are spread and in the field of practice of our Institute. The pomological traits of each of the newly discovered types were studied separately. Here, the weight, color of fruits, stalk length, color and taste of the pulp, the location of the germ cell and the number of seeds in each cell were studied. The tasting prices of the fruits of each of the found types were determined separately. According to the tasting price, Badamli Factory 1, Andamich-2, Sabir village 2 and Milakh-1 types were preferred. Also, the productivity of these types was compared with standard varieties. Here the weight of the fruits of each type and the harvest of each tree were clearly given.

An efficient and low-cost DMPPT approach for photovoltaic submodule based on multi-port DC converter

Solar energy is one of the most promising energy types, but photovoltaic (PV) mismatches have several negative effects. Finding an efficient and low-cost method to reduce or eliminate the power loss caused by the mismatch in PV power generation systems is necessary. In this paper, we propose a PV submodule-distributed maximum power point tracking (DMPPT) scheme based on a multi-port DC converter. In-depth analysis and research are performed on the PV model and mismatch characteristics, the PV module voltage equalization (VE) strategy, and implementation with the multi-port buck–boost converter. We discuss the trade-off between true DMPPT and VE on control overhead and tracking accuracy, and a detailed derivation is created to illustrate the differences between them. The VE can reduce the cost and complexity of the system at the expense of a small PV energy capture. The proposed implementation reduces the number of semiconductor components and current sensors, which is conducive to the integrated design of the hardware. A prototype based on a multi-port buck–boost converter for a 36 V/200 W PV module was designed and built. The feasibility and progress of the proposed scheme were verified through experiments.

SOME CHEMICAL AND PHYSICAL QUALITIES OF COLD-ADAPTED PROMISING WALNUT GENOTYPES:TURKEY, BINGOL REGION

The objective of the present study was to examine some physical and chemical shell and kernel attributes of promising walnut types selected from Bingol province in Turkey. Bingol province possesses a rich walnut population almost all of which are seedling-grown. Shell cracking resistance, kernel firmness, kernel percentage, pellicle and cotyledon color, total oil ratio, total phenol content, and antioxidant capacity as DPPH were analyzed and evaluated. Shell cracking resistance ranged from 8.73 to 34.83 kgf with an average value of 17.96 kgf. Kernel firmness was found to range from 0.87 to 1.34 kgf. Lightness (L*) of pellicle was in range of 47.06 and 63.01 while yellowness (b*) in the range of 25.02 and 31.98. Lightness (L*) of cotyledon changed mildly from 70.76 to 76.47 with a mean of 73.57 while cotyledon yellowness was in the range of 25.49 and 30.34. Total oil ratio was found to vary between 45.04 and 56.88%. Total phenol content was in the range of 80.97 and 142.91 mg.kg-1 with average value of 118.12 mg.kg-1. The DPPH free radical scavenging capacity of the genotypes vaguely varied from 64.14 to 70.52% with a mean of 69.04%. Finding especially shell cracking index, kernel percentage and pellicle color may contribute to walnut improvement programs.

Dynamics of poultry and the current state of poultry in the Western region of Ukraine

One of the most attractive and promising types of agrarian business in Ukraine is poultry farming, the rapid development of which ensures high competitiveness, due to the short period of production, lower compared to other food products of animal origin, price and high demand among consumers. Now, the market of our country has significantly increased demand for turkey meat, which has practically no contraindications, as it does not contain cholesterol, is a gentle, hypoallergenic, dietary product that is rich in unsaturated fatty acids, including omega-3, proteins, essential amino acids, minerals, vitamins A and B, etc. The purpose of the work was to investigate the dynamics of poultry in the period from 2011 to 2020 and to get the current state of poultry in general, and turkey farming in particular, in the Western region of Ukraine. It is found that in the period from 2011 to 2020 the largest number of poultry, 9548.3 ± 447.1 thousand, was kept in farms of Lviv region, slightly less – 8109.1 ± 546,1 thousand of Khmelnytsk region, even less – 7222.1 ± 121.0 and 7682.9 ± 316.2 thousand Volynj and Rivne regions. The farms of Ivano-Frankivsk, Ternopilj, Transcarpathian and Chernivtsi regions was kept 5290.8 ± 284.7 5200.2 ± 86.2, 4127.6 ± 115.2 and 3636.7 ± 50.5 thousand poultry, respectively. The largest poultry population in the farms of Lviv and Volynj regions was in 2020 and amounted to 11938,1 and 8822.4 thousand, respectively, Rivne region – 7742.3 thousand in 2018, Transcarpathian – 4385.8 thousand in 2015, Chernivtsi – 3863.9 thousand in 2012, Ternopilj – 5584.2 thousand in 2019, Khmelnytskyj – 10864.5 thousand in 2014 and Ivano-Frankivsk – 6761.1 thousand in 2011.The lowest number of poultry in farms of Lviv, Rivne, Volynj, Transcarpathian, Ternopilj, Khmelnytskyj regions was in 2011, the number of which was 7961.5, 6721.2, 5933.7, 3126.1, 4681.6, 5069.7 thousand, respectively, and Chernivtsi and Ivano-Frankivsk – 3376.5 and 4175.7 thousand in 2016 and 2017. The smallest number of turkey farms in Western Ukraine was in the period from 2011 to 2013. By 2017, there was an increase in their number by 20 %, and in 2018 – a decrease of 10 % compared to 2017. In 2019, the number of registered enterprises increased by 18.18 %, compared to 2018, and in 2020 their number was the largest.

Analysis of technical and operational characteristics of high-speed vessels - their promising types

The article presents the development trends and a comparative analysis of the technical and operational characteristics of various types of high-speed vessels, which in the future can be used for transport in the Russian Federation.

Promising types of packaging for canned products

The article discusses modern types of packaging for canned products and analyzes their advantages and disadvantages.

Development of technology of highly accessible compound feeds with vacuum spraying of liquid components

The technology of production of compound feeds for agricultural (pigs) and unproductive (dogs, cats) animals, as well as for fur-bearing animals (minks, arctic foxes, sables) and valuable fish (sturgeon, trout, etc.), in which the replacement of expensive components of animal origin (fish meal, meat and bone meal, blood meal, offal), for extruded vegetable high-protein components (soy, sunflower or rapeseed meal, lupine, peas, soy) is carried out. The use of vacuum spraying of thermolabile liquid components (amino acids, protein-vitamin-mineral additives, vitamins, fats) on the surface of extruded pellets will allow you to obtain highly digestible feed. The kinetic regularities of the studied processes of humidification and steaming, extrusion, drying/cooling and draining are determined, and their rational modes are revealed. The technological scheme of the line for the production of highly digestible compound feeds has been developed, which includes the following equipment: hopper; extruder; dryer-cooler; liquid component injection plant, draining machine; conveyor and finished product hopper. According to the technical characteristics (overall dimensions, weight, occupied area, drive power, uniformity of application of fat on the surface of granules), the manufactured coating machine and the liquid component injection unit exceed the best world analogues. The technology of vacuum mixing with the introduction of liquid components will ensure their uniform distribution over the entire volume, reduce the duration of mixing, which will increase the productivity of the vacuum mixer and reduce energy consumption. The developed technology and promising types of technological equipment (mixer, extruder, vacuum sprayer, dryer-cooler) will make it possible to obtain highly digestible feed of a new generation with a protein content of 60 %, fat content of 40 %, with the introduction of growth stimulants, biologically active additives. An increase in the protein and fat complex will increase the digestibility of compound feeds by 10-12 %, increase weight gain by 10-12 % and reduce feed conversion by 15 %.

Укрепление и защита берегов в Калачевском районе Волгоградской области с помощью кустарниковой растительности

The critical abrasion situation manifests itself on the coastal part of the Kalachevsky district due to the increasing anthropogenic load. The most important element of the complex of measures to combat silting of reservoirs and coastal abrasion, as well as an effective measure to strengthen the banks is forest vegetation. The objectives of the research were to study the soil, forest and climatic conditions of the object under study, to develop an assortment of shrubs and features of the formation of protective forest stands, as well as criteria for selecting an adapted assortment of tree and shrub vegetation and methods of caring for the soil and plantings. During the research, the most promising types of shrubs for creating upper protective forest stands were identified: Ligustrum vilgare L., Berberis vulgaris L., Cotoneaster lucidus Schltdl., Amelanchier Medik., Ribes aureum Pursh., Rosa canina L. It was found that the useful role of forest stands is manifested in their ability to convert surface runoff into subsurface runoff, to clean surface stock water from fine-grained soil, to weaken the speed of movement and to extinguish the energy of waves, binding the soil with roots. Recommendations are given for the creation and placement of anti-abrasion plantings, depending on the steepness and height of the slope. It is stated that one of the main measures for the care of the aboveground part of the plantings is the pruning of the crown, carried out taking into account the biological characteristics of their growth and development, including the removal of dry and damaged branches, thinning of the crown, preservation of the previously given crown size, rejuvenation of the crown. It is recommended to place shrubs depending on the landscape, soil and climatic conditions and features of abrasive processes in areas of constant, periodic, episodic flooding and strong moderate and weak flooding of the coastline.

Anionic three-dimensional porous aromatic framework for fast Li-ion conduction

Solid polymer electrolytes (SPEs) have been received significant attention due to their inherent advantages of high safety and high electrochemical stability as fast Li-ion conductors. However, conventional SPEs of dual-ion conductors (i.e., conducting both anions and cations) are prone to induce concentration polarization and thus decrease in ionic conductivities, which remains a significant hurdle for their practical applications. Here, we propose a new host of porous aromatic frameworks (PAFs) as a promising single Li-ion conducting SPEs. PAF1 is one of the promising types for crystalline polymers with the integration of aromatic organic building units into a 3-dimensional framework, having plenty of voids space inside. By covalently tethering the sulfonate on aromatic groups, anions are immobilized onto the frameworks, and the exchanging process of protons with Li-ions makes it perform as a fast Li-ionic conductor. Consequently, Li sulfonated PAF1 (denoted as Li-SPAF1) shows superior ion-conducting properties of 0.102 mS cm−1 at room temperature with the activation energy of 0.21 eV. It is demonstrated that the aromatic groups have high chemical and thermal stabilities, even stable with Li metal, which is advantageous for delivering stable electrochemical performances. Also, the structure and conduction mechanism are theoretically investigated by using density functional theory calculations.

Перспективные направления технологического оснащения производства комбикормов

The promising areas of technological support of compound feed production facilities have been established. The main specifications and advantages and disadvantages of promising types of technical equipment are indicated. Projects of industrial and scientific institutions in the field of feed production that allow reducing the cost and improving the quality of the finished feed have been selected. The main areas of improving technological support using domestic equipment are highlighted.

Tuning Microbial Activity via Programmatic Alteration of Cell/Substrate Interfaces.

A wide portfolio of advanced programmable materials and structures has been developed for biological applications in the last two decades. Particularly, due to their unique properties, semiconducting materials have been utilized in areas of biocomputing, implantable electronics, and healthcare. As a new concept of such programmable material design, biointerfaces based on inorganic semiconducting materials as substrates introduce unconventional paths for bioinformatics and biosensing. In particular, understanding how the properties of a substrate can alter microbial biofilm behavior enables researchers to better characterize and thus create programmable biointerfaces with necessary characteristics on demand. Herein, the current status of advanced microorganism-inorganic biointerfaces is summarized along with types of responses that can be observed in such hybrid systems. This work identifies promising inorganic material types along with target microorganisms that will be critical for future research on programmable biointerfacial structures.

METHODOLOGICAL APPROACHES TO ASSESSMENT OF THE TECHNOLOGY AND INNOVATION LEVEL OF THE INDUSTRY, TAKING INTO ACCOUNT THE MODERN TRENDS OF ITS DEVELOPMENT

The article reveals the stages of the formation of sectoral approach to assessing the level of industrial technology in accordance with international practice. The differences between the categories «technology intensity» and «innovativeness» are determined in accordance with the recommendations of the Organization for Economic Cooperation and Development and regulatory documents of the Republic of Belarus. A comparative assessment is carried out and a much lower intensity of R&D in the manufacturing industry of our country is shown in comparison with international data, which necessitates the intensification of scientific research in the framework of the innovation process. Identified promising types of economic activities that produce products new to the domestic and world markets. Innovative projects for the creation of new industries based on technologies of the V and VI techno-logical modes are presented. The directions and instruments of state innovation policy for 2021–2025 in the field of creating new and accelerating the development of existing high-tech sectors of the economy are proposed.

Strategic analysis of the tourist potential of the Ternopil region

For the development of the economy of the Ternopil region, tourist potential has an extremely important. It is represented by historical and architectural monuments, religious buildings, natural landscapes. The combination of existing tourist resources with natural and climatic conditions, developed transport and tourist infrastructure The tourist potential of the region allows us to create prerequisites for further sustainable tourism development in the region. To study the tourist potential of the Ternopil region, we used a SWOT analysis matrix by which we identified the existing tourist potential of the region, which includes natural resources (water, deposits of peat mud, fauna) and historical and cultural objects (PAM ‘ Architectural people). The article defines the main promising types of tourism, which allow to effectively use existing resources of the region. The purpose of the article: conducting a strategic analysis of the tourist potential of the Ternopil region using the SWOT matrix and the identification of the most promising strategic directions of development of the tourist industry of the region. Research methodology. In the course of conducting research, the following methods of analysis and synthesis are used (when clarifying the essence of the concept of “tourist potential”), generalization (when forming conclusions and determining the priority areas of tourism development in the region), induction and deduction (when forming a SWOT analysis matrix). The scientific novelty of the article is to use SWOT analysis to assess the tourist potential of the region. Conclusions. Application of strategic analysis to evaluate the tourist potential of the region is an effective instrument. He allowed to identify existing resources to identify promising types of tourism and further development of the tourism industry in the region. Key words: tourism, tourist potential, strategic analysis, tourist resources, SWOT analysis.

FUNCTIONAL PURPOSE RABBIT MEAT ROLL

The article presents the results of the development of a new type of rabbit meat product - meatloaf. The consumption of healthy and nutritious foods rich in macro- and micronutrients, low in lipids and cholesterol, as well as various nutritional supplements, is preferable for the modern consumer. One of the promising types of meat as a dietary raw material is rabbit meat. As a result of the studies, a physicochemical analysis was carried out, the amino acid composition of rabbit meat was determined, and an organoleptic and tasting assessment of rabbit meatloaf was given. The technological scheme, the recipe is developed and the technological parameters of the meatloaf preparation are determined. It is recommended to store meatloaf no more than 10 days at a temperature of 0–2 °C with a humidity of 85-90 %. Meatloaf from rabbit meat has functional properties, contains a large number of vitamins PP – 174.3 mg, potassium minerals – 5052.8 mg, magnesium – 382.4 mg, phosphorus – 2875 mg, sodium – 8598.7 mg.The results of the nutritional and biological value of rabbit meatloaf allow us to make an informed conclusion about the high level of their nutritional value, which clearly illustrates the values of quality indicators.

Prospective artificial lift equipment for shale oil production from the Bazhenov formation

The article provides an analysis of shale oil production and artificial lift equipment world market for choosing the optimal method for oil production from the Bazhenov formation. The result of the analysis is the identification of prospective complexes of artificial lift (wellhead and downhole) equipment that meet the following conditions:
 • artificial lift equipment is used in operating conditions that are similar to those, which planned for the Bazhenov formation development: for wells with a long horizontal wellbore and multi-stage hydraulic fracturing; conditions similar to the Bazhenov formation in terms of the depth of the deposit, production volumes (production curve, initial flow rates, gas-oil ratio (GOR), reservoir temperature, etc ).;
 • the properties of the produced fluid are similar to the Bazhenov formation reservoir fluid (light oil, GOR increase over production time, water cut drop over time, etc.
 Analysis includes wellhead equipment, downhole equipment, and control stations for wellhead and downhole equipment.
 Based on the analysis results, the main selection criteria are given, a comparative analysis of the main types of artificial lift equipment is carried out, and promising types of artificial lift for oil production from the Bazhenov formation are identified.