With the rapid development of modern science and technology, computer technology has been widely used in various industrial fields of society, and the education industry is no exception. The application of virtual reality technology in clothing design has greatly improved the efficiency of designers in the redesign process and perfected the wearing effect of clothing. In the face of the future demand for innovative design talents, cultivating talents who meet the requirements of clothing design is an important issue and task for university teaching. At present, there are problems in the teaching of clothing design profession such as single traditional teaching mode, weak creativity of students' works, disconnection between teaching content and practice, imperfect teaching resources and imperfect teaching details. In this paper, virtual reality technology is introduced to reform the curriculum system of the clothing profession through a mixed research approach, using experimental project-based teaching combined with quantitative research methods. Through practice, it is proven that the integration of virtual technology into apparel teaching creates a simulation effect for teachers and students that cannot be matched in the traditional apparel design teaching process and enhances students' interest in learning. The application of virtual reality technology is a new and efficient teaching method that has emerged in recent years with the development of computers, combining technology and art, and based on the teaching of clothing design projects, which greatly improves learning efficiency and teaching effectiveness and can effectively improve students' innovation ability, and has a broad development prospect.