BACKGROUND: A pressure ulcer (PU), also known as bedsore, pressure injury, or decubitus ulcer, is a localized injury brought on by sustained pressure applied to the skin and underlying soft tissue over an extended length of time. This study aimed to identify the outcome and challenges of the application of pressure ulcer prevention project focus to clarify the findings of the application of the project, to highlight the challenges met by the team who apply the project, to know the prevalence state during the application period, and to identify the adherence of nurses to their role. Through Improved nursing education, improve adherence to a policy of pressure ulcer prevention, being sure all equipment is in adequate working condition, Monitoring high-risk patients.
 
 METHODOLOGY: This is a retrospective hospital-based study, which monitored the pressure ulcer prevention project’s (PUPP) results from 2019 to 2021 for 3 years. Data on 21400 patients were gathered from several departments of a hospital in the west region of Saudi Arabia. The project’s main goals were the installation of a wound care team, hospital staff education, ongoing data monitoring, and follow-up visits for inpatient units.
 
 RESULTS: This current study showed that the pressure ulcer prevention project was successful showing a statistically significant reduction of hospital-acquired pressure ulcers (HAPUs) from 1.97% in 2018 to 1.4% in 2019 to 0.53% in 2020 to 0.14% in 2021. 
 
 CONCLUSION: The research concluded the percentage of cases of pressure ulcers was successfully decreased by the PUPP. The project can be expanded and carried out in additional hospitals.