Pressure Slope Research Articles

Instability and its prediction of an inverted inhomogeneous plate loaded by a subsonic airflow: Theory and experiment

This paper presents a study on the instability of an inverted cantilevered plate with an inhomogeneous cross-section in axial flow from both theory and experiment. The plate is free at the leading edge and clamped at the trailing one. It has a cross-section with discontinuity, bringing difficulty in solving the fluid–structure interaction equation by the traditional methods. We study this problem in state space and transfer its solution into a function approximation problem. We bring no approximation at the first equation level, and the derived instability equation is on the continuum. A numerical scheme is proposed to solve the instability equation. Series expansion and least square method apply to the numerical solutions. The convergence and reliability of the present method are entirely tested. This present modeling method preserves the original information of the problem and facilitates the exploration of the effects of inhomogeneity. Based on the present continuum instability equation, prediction formulas for critical dynamic pressure and instability slope of an inhomogeneous plate are first given and verified. They can apply to the stability prediction of arbitrary cross-sectional plates and have application potential for the plate design. In addition, we report an optimized stiffness distribution of the plate for the maximum critical dynamic pressure. Finally, a wind tunnel test is designed and implemented. A comparative study shows that the present method and prediction formula agree well with the experiment. The present modeling method for a fluid–structure interaction problem in a continuous sense, avoiding approximation at the beginning level, can serve as another new way to address the static instability problem of plates.

RENAL11: Novel Clog-Based Switch to Surveille Peritoneal Dialysate for Peritonitis

Background: Quickly triaging patients on Peritoneal Dialysis (PD) for infection is critical for patient-health outcomes. The best methods of detection, such as blood panels or sample culture, are not suited for quick point-of-care applications. The current detection method is by visual inspection of the fluid by the patient who looks for ‘cloudiness’ in the spent dialysate. Peritoneal dialysis, a type of renal replacement therapy for patients with end-stage renal disease (ESRD), has a survival advantage for the first two years of use over hemodialysis (HD). Other advantages of PD over HD include higher patient satisfaction and lower costs. The main shortcoming of PD is the patients’ increased susceptibility to peritonitis due to the permanent catheter that provides access to the peritoneal cavity for fluid exchanges. The infection can create life-threatening situations for patients. Importantly, for most patients using PD, repeated peritonitis can result in peritoneal membrane failure, necessitating a switch to HD with its associated disadvantages. Preemptive monitoring is currently not available in clinical practice of PD. The current detection method is by visual inspection of the fluid by the patient who looks for ‘cloudiness’ in the spent dialysate. Progress has been made to reduce the incidence of peritonitis, but detection remains problematic. Methods: To achieve this goal, we have developed a novel switch to detect the presence of dangerous levels of WBC in spent peritoneal dialysate (see Figure 1). Since the sensitivity of a clog-based sensor is dependent on the permeability of its membranes, incorporating highly permeable silicon nanomembranes into a white blood cell detector will produce a highly sensitive WBC detector. Spent Dialysate from peritoneal dialysis fluid exchanges (spike the dialysate with varying amounts of WBCs) is pushed at 200 µL/min into the top channel with the top outlet open to the atmosphere. The inlet of the bottom channel is closed, and the outlet pulls at 100 µL/min through the membrane. If the membrane is clogged the transmembrane pressure (recorded for the duration of the experiment at ~0.5-second intervals) will increase. Results: We have preliminary data demonstrating that membranes with 4-µm wide microslit pores block the passage of WBCs while allowing all other cells and proteins in whole blood to pass. Figure 2 shows the pressure increase across the membrane when subjected to varying concentrations of white blood cells in spent dialysate. The slope of the pressure indicates the WBC count. The primary innovation comes from the use of microporous membranes as a fouling-based sensor; using membranes with pores tuned to be just slightly smaller than the size of leukocytes, we will see a change in the transmembrane pressure (under a steady flow rate) as the WBCs block pores which correlates to the WBC concentration.Figure 1. a: Schematic showing WBC-detection switch. Pressure transducers report pressure increase as cells clog the membrane. b: WBCs are drawn to the micropores by transmembrane flow.Figure 2. Transmembrane pressure slope correlates with the white blood cell concentration in the dialysate.

Effects of ambient pressure on smoke propagation in inclined tunnel fires under natural ventilation

This paper systematically studied the coupling effect of ambient pressure and tunnel slope on temperature distribution and smoke propagation in full-scale tunnel fires under natural ventilation by FDS. The downstream length (longitudinal length from fire source center to tunnel downstream exit) was also considered. The concept of "height difference of stack effect" was put forward when analyzing the mutual effect of tunnel slope and downstream length on smoke movement. The results show that the maximum smoke temperature beneath the ceiling decreases with the increasing ambient pressure or tunnel slope. The longitudinal smoke temperature decays faster with the decreasing ambient pressure or slope in inclined tunnel. The induced inlet airflow velocity increases with the increasing height difference of stack effect, while decreases with the increasing ambient pressure. And the smoke backlayering length decreases with the increasing height difference of stack effect. Taking heat release rate (HRR), ambient pressure, tunnel slope and downstream length into account, the prediction models of dimensionless induced inlet airflow velocity and smoke backlayering length in inclined tunnel fires at high altitude were developed, which agree well with our and others' results. The outcomes of current study are great meaningful to fire detection and smoke control in inclined tunnel fires at high altitude.

Centrifuge model studies on the performance of earthen dams with geocomposite internal drain subjected to pseudostatic seismic loading

This paper evaluates geocomposite (GC) as an internal drain for seepage control in earthen dams subjected to upstream impoundment and inertial loading through centrifuge model tests. A total of five centrifuge tests were performed on a homogeneously built small earthen dam section having prototype height of 7.2 m with 1H:1V side slopes at 30 g-level using a 4.5 m radius large beam geotechnical centrifuge available at the Indian Institute of Technology Bombay, India. The studied earthen dam models had an internal drain in the form of (a) a geocomposite horizontal drain (GC HD); (b) a sand-sandwiched geocomposite horizontal drain (SSGC HD); (c) a geocomposite chimney drain (GC CD); and (d) a sand-sandwiched geocomposite chimney drain (SSGC CD). The seepage-deformation response of the GC equipped earthen dam models is presented in terms of the development of pore-water pressure (PWP), phreatic surfaces, surface settlements (sc), and downstream slope face movements (sf). The behavior of the earthen dam model without any internal drain is also presented for comparison. In the case of an earthen dam with GC internal drain both as HD and CD, it was found to be efficient up to some extent in restricting phreatic surfaces, but phreatic surfaces were observed to be close to downstream side slope. However, a sand-sandwiched GC internal drain HD and CD seemed more promising in restricting the phreatic surface much within the downstream region and imparting higher stability even during sustained inertial loading conditions. The study concludes that SSGC chimney drain can be safely adopted for seepage control in small earthen dams and similar geotechnical structures viz levees, raw water reservoirs (RWRs), coastal protection structures, etc.

Abstract P349: Predictive Value of Long-Term Systolic Blood Pressure Variability for the Development of Type 2 Diabetes Mellitus

Background: Better identification of high-risk individuals of type 2 diabetes mellitus (T2DM) for focused delivery of preventive measures requires risk prediction models using novel predictors. We evaluated the predictive value of long-term variability of systolic blood pressure (SBPV), which was recently reported to be associated with T2DM incidence, if added to a model with conventional T2DM predictors in a Japanese cohort study. Methods: A cohort of 3017 Japanese individuals (2446 male, 571 female) ages 36-65 years were followed from 2007 to 2019. Root-mean-square error (RMSE) and slope of systolic blood pressure (SBP) change regressed on year were calculated per individual using SBP values obtained consecutively from 2003 to 2007 to represent SBPV. An initial Cox model included age, sex, smoking status, regular exercise, family history of diabetes, body mass index (BMI), baseline SBP, blood levels of triglycerides (TG), high-density lipoprotein cholesterol (HDLC) and fasting blood glucose (FBG), and backward elimination was used for variable selection. The c-statistics, net reclassification improvement (NRI) and integrated discrimination improvement (IDI) were used to compare the performance of prediction models without (Model 1) and with SBPV (Model 2). Results: During 9.8-year (median) follow-up, 135 developed T2DM. We confirmed that RMSE was significantly associated with T2DM incidence independent of other variables used in a conventional model. Backwards elimination procedure selected BMI, TG, HDLC, FBG, SBP RMSE, and SBP slope for the final model (Table 1). Although the c-indices were not statistically different between Model 1 (0.77) and Model 2 (0.78) as well as the NRI (7.1%), the IDI was statistically significant (0.8%, p<0.05). Conclusions: The present study revealed that long-term variability of SBP slightly improved the predictive value of T2DM if added to a conventional prediction model.

Qualitative Evaluation of Intracranial Pressure Slopes in Patients Undergoing Brain Death Protocol

Due to the importance of not mistaking when determining the brain death (BD) diagnostic, reliable confirmatory exams should be performed to enhance its security. This study aims to evaluate the intracranial pressure (ICP) pulse morphology behavior in brain-dead patients through a noninvasive monitoring system. A pilot case-control study was conducted in adults that met the BD national protocol criteria. Quantitative parameters from the ICP waveforms, such as the P2/P1 ratio, time-to-peak (TTP) and pulse amplitude (AMP) were extracted and analyzed comparing BD patients and health subjects. Fifteen patients were included, and 6172 waveforms were analyzed. ICP waveforms presented substantial differences amidst BD patients when compared to the control group, especially AMP, which had lower values in patients diagnosed with BD (p < 0.0001) and the TTP median (p < 0.00001), but no significance was found for the P2/P1 ratio (p = 0.8). The area under curve for combination of parameters on the BD prediction was 0.77. In this exploratory study, noninvasive ICP waveforms have shown potential as a screening method in patients with suspected brain death. Future studies should be carried out in a larger population.

Effect of the Discharging Flap on Particle Separation in a Cyclone

AbstractThe flow field, pressure drop, and separation efficiency of an industrial cyclone separator were computationally investigated using the Reynolds stress model simulations. The effects of the flapper valve on the static pressure drop, cut size, and slope of the grade efficiency curve were revealed. For that, the cyclone was simulated in three operation regimes, when the flapper valve is open, closed, and without the flapper valve. The results showed that a flapper valve increases the cyclone cut size by 3.4 % when it is in the position “closed” and by 11.4 % when it is in the position “open”. The slope of the grade efficiency curve increases when a valve is switched to the position “open” but the static pressure drop increases by 4.8 % when a flapper valve is in the position “closed”.

Experimental and numerical investigation of transient starting of pre-evacuated exhaust diffuser in high altitude ground test

This paper deals with numerical and experimental investigation of exhaust diffuser transient starting in a high-altitude ground test of a thrust optimized parabolic (TOP) nozzle. The experimental investigation has focused on cold gas flow inside TOP nozzle and second throat exhaust diffuser (STED), performed to examine flow unsteadiness at the starting phase. In order to identify physical phenomena during STED starting, unsteady numerical simulations have also been carried out. Two major parameters including nozzle pressure slope and pre-evacuated regions along the diffuser have been examined. The results indicate elimination of the cap shock separation or restricted shock separation (RSS) pattern during the transient starting at high nozzle pressure slope with pre-evacuation. Also, considerable reduction in the starting time is achieved, so that it causes more desirable instantaneous starting of the diffuser in some conditions. However, at average and lower nozzle pressure slopes, RSS pattern still develops inside the nozzle. Investigation of the effect of pre-evacuation spaces along the diffuser on the course of evacuation development indicates that the larger the pre-evacuation space along the diffuser, the more desirable is the STED operation quality, whereby the starting time decreases considerably. It is shown that with a given nozzle pressure slop, enlarging the pre-evacuation area from the diffuser inlet to the middle of the second throat results in a 25% reduction in diffuser starting time, and the further increase of the pre-evacuation area to the end section of the diffuser leads to instantaneous starting of the diffuser. Furthermore, we found that initial pre-evacuation pressure value has less effect on the diffuser starting process, so that for a given nozzle pressure slop and a pre-evacuation area by reducing this parameter five times, the starting time is reduced by only 3.75%.

Slope Stability Prediction Method Based on Intelligent Optimization and Machine Learning Algorithms

Slope engineering is a type of complex system engineering that is mostly involved in water conservancy and civil and mining engineering. Moreover, the link between slope stability and engineering safety is quite close. This study took the stable state of the slope as the prediction object and used the unit weight, cohesion, internal friction angle, pore water pressure coefficient, slope angle, and slope height as prediction indices to analyze the slope stability based on the collection of 117 slope data points. The genetic algorithm was used to solve the hyperparameters of machine learning algorithms by simulating the phenomena of reproduction, hybridization, and mutation in the natural selection and natural genetic processes. Five algorithms were used, including the support vector machine, random forest, nearest neighbor, decision tree, and gradient boosting machine models. Finally, all of the obtained stability prediction results were compared. The prediction outcomes were analyzed using the confusion matrix, receiver characteristic operator (ROC), and area under the curve (AUC) value. The AUC values of all machine learning prediction results were between 0.824 and 0.964, showing excellent performance. Considering the AUC value, accuracy, and other factors, the random forest algorithm with KS cutoff was determined to be the optimal model, and the relative importance of the influencing variables was studied. The results show that cohesion was the factor that most affects slope stability, and the influence factor was 0.327. This study proves the effectiveness of the integrated techniques for slope stability prediction, makes essential suggestions for future slope stability analysis, and may be extensively applied in other industrial projects.

Pressure And Spacer Effect On The Performance Of Immersed Microfiltration Membrane

The water treatment applied in PDAM Surabaya City to treat Kali Surabaya still uses a conventional process where the treatment process will get even harder with decreasing quality of raw water. Immersed microfiltration membrane is a reliable technology in water treatment compared to conventional technology. Nevertheless, the performance of the membrane decreases due to deposits that occur on the membrane surface and lead to fouling. This study aims to examine the effect of pressure and spacers on the performance of microfiltration ceramic membrane measured based on quality and quantity parameters. The research parameters used were turbidity, TSS, organic matter, total coliform, E. Coli and the number of microplastic while the quantity parameters included flux, amount of water production and the duration of membrane operation before fouling. This study tested immersed flat-sheet microfiltration ceramic membranes in sedimentation unit of PDAM Ngagel III Surabaya City. Membrane operation used cross-flow with variable pressure (0.6 bar, 0.7 bar, 0.9 bar) and spacer slopes (75°, 90°, 105° and without spacers). Based on the results of the study, it was found that the effect of optimal pressure occurred at 0.7 bar with the efficiency of eliminating turbidity, TSS, organic matter, microplastic, total coliform, and E. Coli parameters respectively, 94.66%, 96.88%, 24.29%, 62.27%, 100% and 100%. The average flux value at pressure 0.7 bar is 64,33 L/m2.hour with operating duration of 55 hours and permeate production volume 530.70 L. The optimal spacer effect was achieved at slope of 90° with the efficiency of eliminating turbidity, TSS, organic matter, microplastic, total coliform and E. Coli parameters respectively 95.12%, 64.58%, 28.75%, 84.74%, 99.99% and 100%. The average flux value was 66,78 L/m2.hour with an operating duration of 90 hours and permeate production volume 901.55 L.

Study on fracture development and progressive failure characteristics of downstream dam-type expansion tailings reservoir

With the economic development and industrialization, the increasingly accumulated tailings ponds in China have become a great risk. Due to the difficulty of selecting proper site for a new reservoir in Yunnan, a sub-dam was built at the downstream original reservoir. This study explored the fracture development and progressive failure characteristics of the tailings reservoir area after capacity expansion based on a similarity experiment and the numerical simulation. The results showed that the primary cracks in the reservoir area were more than those at the top of the sub-dam. With the increase of the upper load, the primary cracks further developed and penetrated the whole sub-dam top, and the sub-cracks were then produced under the concentrate stress of the primary cracks. After the further development of the sub-cracks, the secondary cracks parallel to the primary cracks were formed on the outer slope of the sub-dam. The progressive failure of a tailings dam can be summarized as: the maximum shear stress was firstly generated at the toe of the slope or the top of the dam which then extended to the top of the sub-dam in the form of a curve and finally formed the failure surface by connecting with the primary fracture of the tensile plastic zone at the top of the dam. The study also found that in the process of tailings accumulation in the new reservoir area, tailings would form "back pressure slope protection" at the initial dam of the original reservoir, which not only effectively delayed the occurrence of shear failure, but also inhibited the generation and penetration of tensile plastic zone.

Numerical Investigation of the Strain Characteristics of a Natural Gas Transportation Pipeline Crossing Tunnel

To ensure the safe operation of a natural gas transportation pipeline (NGTP) crossing tunnel, a model is established to analyze the strain characteristics. Some factors affecting the strain are considered in this paper. The results show that the strain failure of a NGTP crossing tunnel may occur in the two elbows of the NGTP located at the tunnel entrance and the position in contact with the fixed pipe clamp near the tunnel entrance. At the same time, the strain of the NGTP crossing tunnel is obviously affected by the temperature change of natural gas. So, the temperature change should be controlled within 8 K in the actual operation process. The wall thickness, the length of the NGTP, and the slope angle of the crossing tunnel are also main factors to affect the strain of the NGTP crossing tunnel, while the operation pressure and mountain slope angle have little effect when the operation pressure is 6–11 MPa. The maximum value of Mises equivalent strain is also obviously affected by the pipe diameter when it is more than 273 mm. Meanwhile, a prediction model for the maximum value of Mises equivalent strain is also established by the nonlinear fitting method and the deviation is within ±15% between the calculations and simulation results. The above conclusions will provide a theoretical basis and data support for the safe operation and design of NGTP crossing tunnels.

Seismic geomorphology of the Chandeleur submarine landslide in the northern Gulf of Mexico

Abstract The Chandeleur Submarine Landslide Complex occurs on the upper Mississippi Fan of the Gulf of Mexico in approximately 1100 m of water, 200 km SE of New Orleans, Louisiana. This part of the Mississippi Fan received high sedimentation throughout the Pleistocene, causing high pore fluid pressure and abundant slope failures, though few as large as the Chandeleur. Given its large size, proximity to major coastal cities and seafloor infrastructures, we examine the Chandeleur Slide to understand what led to the initial slope failure and decipher its post-failure transport behaviour using 2D and 3D multichannel seismic surveys, high-resolution bathymetric data, and well logs. We find a large sediment mass with a translational-rotational behaviour that was displaced to the south/SE up to 40 km from the source area. The Chandeleur Slide includes extensional faulting in the headscarp area and compressional structures in the toe where confined by a natural ramp-like structure. Beneath the Chandeleur Slide, we identify a regional sand-rich unit (called the Blue Unit) that is known to be overpressured. Beneath the Blue Unit we observe an upward-migrating salt diapir. We suggest one possible scenario for the origin of the Chandeleur Slide is the combined effects of an upward-migrating salt diapir impinging on an already overpressured Blue Unit, leading to the initial failure. The initial failure was followed by retrogressive headwall retreat northward, which created the prominent scarp on the seafloor. In total, the Chandeleur Slide complex covers an area of about 1000 km 2 and contains about 300 km 3 of sediment.

Nonstationary Poiseuille flow of a non-Newtonian fluid with the shear rate-dependent viscosity

Abstract A nonstationary Poiseuille flow of a non-Newtonian fluid with the shear rate dependent viscosity is considered. This problem is nonlinear and nonlocal in time and inverse to the nonlinear heat equation. The provided mathematical analysis includes the proof of the existence, uniqueness, regularity, and stability of the velocity and the pressure slope for a given flux carrier and of the exponential decay of the solution as the time variable goes to infinity for the exponentially decaying flux.

Diagnosis model of shale gas fracture network fracturing operation pressure curves

Affected by reservoir heterogeneity, developed natural fractures, and bedding fractures, the fracturing pressure curves in fracturing of shale gas horizontal wells present complex shapes. A large amount of information contained in the fracturing curves is still not fully excavated. Based on the theory of shale gas fracture network fracturing, the calculation model of bottom hole net pressure is established by integrating the real-time data such as casing pressure, pump rate, and proppant concentration. Net pressure slope and net pressure index are constructed as key parameters, and the net pressure curve is divided dynamically to describe the mechanical conditions corresponding to the fracture propagation behavior during the fracturing process. Six fracture propagation modes were identified, including fracture network propagation, fracture propagation blockage, normal fracture propagation, fracture propagation long bedding, fracture height growth, and rapid fluid filtration, and then the operation pressure curve diagnosis and identification method were formed for shale gas fracture network fracturing in horizontal wells. The shortcomings of conventional operation curve diagnosis and identification methods are abandoned and the fracture network complexity index is presented. The higher index indicates more time of fracture network propagation and fracture propagation along bedding and the better reservoir stimulation effect. The model is applied to shale gas wells in the southeastern margin of Sichuan Basin, and the average fracture network complexity index of a single well is 0.3, which is in good agreement with the microseismic monitoring results. This proves the good reliability of the method developed. The method is helpful to improve the potential and level of fracturing stimulation of shale reservoirs and is of great significance for improving the post-fracturing evaluation technology of fracture network and guiding the real-time dynamic adjustment of field fracturing operations.

The description of fluid criticality by cusp equation of state: Scaling is no longer unique one

We introduce the concept of changeable covolume reaching at the critical point maximum - twice the value of van-der Waals covolume and obeying an empirical power law with critical exponent γ−1 and amplitude E0. On this base and proposed earlier cusp equation of state, we developed an explicit non-parametric equation of state for critical region that describes critical phenomena as an alternative to scaling. We get (i) - a relation between amplitudes D0B0δ−1=E0G0 were the last amplitude is the slope of saturated pressure at the critical point; (ii) – power law for diameter with critical exponent 1−α and amplitude E0B02/(3δ+6); (iii) – complex of amplitudes above Γ0+G0E0=1 and below the critical point δΓ0−G0E0=1; (iv) - universal strength of Yang-Yang anomaly.

Jeremiah Stamler, MD (1919-2022).

Jeremiah Stamler, MD (1919-2022).

Stability analysis of rock slope and calculation of rock lateral pressure in foundation pit with structural plane and cave development

In this study, numerical simulations were carried out to analyze the influence of caves in different positions and shapes, in combination with structural planes, on the stability of the slope and the failure characteristics of a rock slope in a deep foundation pit with high inclination structural planes and cave development. The schemes for substituting a single karst cave for karst caves were constructed. Based on the penetration failure characteristics of karst caves between parallel structural planes, calculation methods for the safety factor of the rock foundation pits and the upper bound of the lateral pressure of supporting structures under the combined influence of the caves and structural planes have been developed, which can be used to assess the safety factor of a rock mass and to calculate the lateral pressure under complex geological conditions. The example of Xuzhou Metro Line 3 Sanhuan South Road Station is taken as an example to verify. The displacement calculation results show that the proposed rock and soil pressure calculation method is close to the actual measured value.

Equal compressibility structural phase transition of molybdenum at high pressure

We have studied the high-pressure compression behavior of molybdenum up to 60 GPa by synchrotron radial x-ray diffraction (RXRD) in a diamond anvil cell (DAC). It is found that all diffraction peaks of molybdenum undergo a split at around 27 GPa, and we believe that a phase transition from a body-centered cubic structure to a rhombohedral structure at room pressure has occurred. The slope of pressure–volume curve shows continuity before and after this phase transition, when fitting the pressure–volume curves of the body-centered cubic structure at low pressure and the rhombohedral structure at high pressure. A bulk modulus of 261.3 (2.7) GPa and a first-order derivative of the bulk modulus of 4.15 (0.14) are obtained by using the nonhydrostatic compression data at the angle ψ = 54.7° between the diffracting plane normal and stress axis.

Left ventricular myocardial work indices in pediatric hypertension: correlations with conventional echocardiographic assessment and subphenotyping.

Myocardial work (MW) is a novel parameter that incorporates non-invasive estimates of left ventricular (LV) systolic pressure into the interpretation of strain, thus overcoming the limitations of load dependency traditionally encountered with LV fractional shortening (LVFS), ejection fraction (LVEF), and global longitudinal strain (GLS). However, data on MW in the pediatric population with hypertension are lacking. Conventional markers of LV function and MW indices were obtained from 88 echocardiographic examinations in 76 children with hypertension (47 males, 15.5 ± 2.96years). When compared with a previously published cohort of 52 healthy controls, global work index (GWI) and global constructive work (GCW) were both significantly elevated while LVEF and GLS were not impaired but rather mildly increased. On multivariable analysis, GWI was correlated with systolic blood pressure (slope = + 16, p < 0.001) and GLS (slope = -100, p < 0.001), while GCW was correlated with systolic blood pressure (slope = + 18, p < 0.001), GLS (slope = -101, p < 0.001), male sex (slope = -75, p = 0.016), and LV mass (slope = -0.93, p < 0.001). Global wasted work (GWW) was correlated with age at echo visit (slope = -4.5, p = 0.005) and GLS (slope = + 5.5, p < 0.001). The opposite occurred for global work efficiency (GWE; slope = + 0.20, p = 0.011, and slope = -0.48, p < 0.001, respectively). Principal component analysis and k-means clustering revealed 4 subphenotypes which differed in terms of etiology, afterload, and compensation stage of the disease. Conclusion: Non-invasive MW shows a good correlation with conventional markers of LV function and may help refine the assessment of hypertensive heart disease in children. What is Known: •Myocardial work (MW) is a novel parameter that incorporates non-invasive estimates of left ventricular (LV) systolic pressure into the interpretation of strain, thereby accounting for both deformation and afterload. • Although the usefulness of MW in the assessment of myocardial function beyond conventional markers has been demonstrated in various clinical populations, data in the pediatric population with hypertension are currently lacking. What is New: •Compared to normal values in healthy children, global work index and global constructive work were increased in those with hypertension, while LV ejection fraction and global longitudinal strain were not impaired. •Machine learning identified 4 subphenotypes which differed in terms of etiology, afterload, and compensation stage of the disease.