This study aims to carefully review published articles examining the effect of active rest with exercise to prevent the risk of musculoskeletal injuries among pharmacy workers. Using the systematic literature review method, data were obtained from a thorough search on Google Scholar. The keywords were "Active Rest AND Exercise AND Injury Risk AND Musculoskeletal AND Pharmacy Worker AND Ergonomics". Additionally, inclusion and exclusion criteria were applied to select articles that align with the study objective. For example, it focused on articles indexed in the Scopus database and published between 2019 and 2024. For standard operationalization, this study followed the PRISMA method. Based on the search results, 6,850 articles were found from various sources. Furthermore, the articles went through several stages of the screening process, in which 8 articles that fit the theme and met the inclusion requirements were selected. The results of this study found that active rest programs had a positive impact on the work productivity, physical activity, and physical fitness of pharmacy workers. In addition, an occupational safety and health (OSH) program, a supportive work environment, and the promotion of an active lifestyle with exercise were also important in improving productivity. Adjustment of active rest programs for specific types of workers, effective behavior change interventions, ergonomic education, and multimodal physical therapy have been shown to reduce the risk of musculoskeletal disorders. The findings of this study support the assumption that a comprehensive intervention program can prevent musculoskeletal injuries, improve employee well-being and comfort, and provide guidance for healthcare practitioners and pharmaceutical company managers in designing effective active rest programs.
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