Background: The skill of intravenous cannulation must be practiced regularly to maintain a high level of competency. This is important to gain quick and efficient intravenous access in populations when required. The insertion of intravenous catheters into peripheral veins is probably the most commonly performed invasive medical procedure in hospitals. This procedure could be difficult sometimes requiring several attempts and causing distress to patients. The high success rates of nurses in intravenous cannulation have been due to the frequent performance of intravenous cannulation Objectives: 1. To assess the existing knowledge regarding intravenous cannulation among staff nurses working in selected hospital. 2. To observe the existing practice regarding intravenous cannulation among nurses. 3. To assess the effectiveness of lecture cum demonstration regarding Intravenous cannulation among staff nurses. 4. To observe the practice of staff nurses regarding intravenous cannulation after lecture cum demonstration. 5. To correlate the knowledge and practice of staff nurses regarding intravenous cannulation .Methodology: Pre experimental one group pre test post test design. Material: Structured knowledge questionnaire and Observational checklist adopted as per WHO guidelines.Sample size: 60. Result: Among the 60 samples, according to age, 39(65%)of subjects were of 21-30 years of age, 14(23.33%) were of 31-40 years, 7(11.67%) were of 41-50 years and no subjects were above 50 yearsAccording to the educational qualification, 38(58.33%) of the subjects were with the qualification of general nurse midwives, 12(20%) were B.sc nursing, 13(21.67%) were PB.B.sc Nursing.Majority of the subjects 45% have work experience of less than 2 years, 23.33% have 3-5 years, 20% have 6-8 years and 11.67% of them have work experience of more than 8 years In relation to area of work, 26.67% of the subjects each were from the Medicine ward and surgical ward, 21.66%were from Intensive care unit and 25% of them were from Casualty/Emergency ward. post test majority of the subjects gained Knowledge regarding intravenous cannulation. 34 (56.67%) subjects had good level of Knowledge score and 23(43.33%) subjects had average level of Knowledge. None of the samples have poor level of Knowledge. the post test the findings shows that 57(95%) subjects had satisfactory level of practice whereas only 3(5%) of subjects had unsatisfactory level of practice. The mean pretest knowledge score was 15.28 and post test knowledge score was 26.58. The mean practice score 7.61 and posttest practice score was 13.76. Student’s paired ‘t’ test is applied at 5% level of significance and The calculated‘t’ value for overall knowledge score of subjects was 35.51 and the calculated ‘t’ value for overall practice score of subjects was 23.44 that statistically interpreted that the lecture cum demonstration regarding intravenous cannulation was effective in increasing the Knowledge and practice of subject. There was significant association between selected demographic variable of year of experience with their pretest knowledge, whereas other demographic variables are not significantly associated.The correlation coefficient of post test knowledge and post test practice score was ‘r’ 0.21, which is indicates a positive correlation. Conclusion: The knowledge of the target population was significantly increased, and there was significant improvement in the level of practice after receiving lecture cum demonstration regarding intravenous cannulation. The improvement in knowledge and practice was found in all subjects irrespective of their demographic variable
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