Technologies for gas conversion have attracted more serious attention, but energy efficiency, supply deficiencies, as well as other risks undermining the gas supply industry, make it difficult to achieve sustainability in gas supply in Ghana. This study explored strategies for improving supplies for sustainable power generation in Ghana. Specifically, the study investigates the risks associated with the gas supply industry and also investigates strategies for improving gas supplies in Ghana. A descriptive study that applied both qualitative and quantitative tools was applied to data collection and analysis to allow for an in-depth analysis of the findings of the research. The population was concentrated on the regulators (Energy Commission) and consumers (VRA and Sunon Asogli, and GNGC/Eni in the supply domains. In all, 357 population was targeted with a sample of 151. Probability (simple random sampling) and non-probability (purposive) sampling approaches were applied to source participants for the study. Statistical inferential tools that guided the analysis included means, standard deviation, Relative Importance Index (RII). The study identified issues of power sector debt due to the weak financial background of the gas supply sector, poor infrastructure, issues of corruption created by delays, poor transparency and weak regulatory framework as key risk factors in the gas supply industry in Ghana. The study also concluded that strategies to support the drive to achieve sustainability in the gas supply industry should involve a planned action towards providing regular and improved infrastructure in transportation and gas supply pipelines to enhance the visibility of the local gas industry and to also meet both domestic and industrial demand for gas products. Again, there should be the establishment and maintenance of functional gas-related policies and regulators, as well as an emergency supply plan to address any shocks that may tend to impact the gas supply industry in Ghana.