This work proposes a new moment-SOS hierarchy, called CS-TSSOS , for solving large-scale sparse polynomial optimization problems. Its novelty is to exploit simultaneously correlative sparsity and term sparsity by combining advantages of two existing frameworks for sparse polynomial optimization. The former is due to Waki et al. [ 40 ] while the latter was initially proposed by Wang et al. [ 42 ] and later exploited in the TSSOS hierarchy [ 46 , 47 ]. In doing so we obtain CS-TSSOS—a two-level hierarchy of semidefinite programming relaxations with (i) the crucial property to involve blocks of SDP matrices and (ii) the guarantee of convergence to the global optimum under certain conditions. We demonstrate its efficiency and scalability on several large-scale instances of the celebrated Max-Cut problem and the important industrial optimal power flow problem, involving up to six thousand variables and tens of thousands of constraints.