The article analyzes the issue of the Middle East security. The Arab countries are facing a lot of regional threats and a fundamental shift in the regional security system, which has become one of the basic variables for the Middle East through the transition to a new form of regional and international interactions. The existence of mutual influences between the nature of the international system and the regional order of the Middle East and the Gulf region is already considered as an incubator for all intractable conflicts and crises. We cannot study the concept of regional security in separate from the global effects and repercussions. After the end of the Cold War and after the collapse of the Soviet Union in 1991, the structural transformations and global changes led to the emergence of profound changes in the international system, which resulted in the restructuring of the general features of the international environment. The international transformation is marked by the fact that the new world order increased the chances of emergence of new international powers in both Europe and Asia, whether countries or major economic or political blocs trying to establish a multi-polar international order, which prompted the United States to pursue a policy of cooperation with competing powers. And in light of this international environment, it was natural for the regions of strategic importance, particularly the Middle East, to be affected because they were linked to relations of mutual influence with the international system, as international balances affect regional balances.