The information age has put forward higher requirements for the professional level of accounting talents, which not only pays attention to the accumulation of knowledge, the improvement of ability, but also pays more attention to the cultivation of professional ethics. As an important base for personnel training, colleges and universities need to give full play to their education functions and train more professionals to meet the needs of social work in the new era. Combined with the background direction of the development of the industry in the new era, based on professional values, and based on the teaching reform of accounting major in colleges and universities as the research background, this paper analyzes the necessity of teaching reform of accounting major in colleges and universities based on professional values, and discusses the teaching reform mode of accounting major in colleges and universities based on professional values from the aspects of goal orientation, platform building, content construction, etc. And put forward the corresponding practical countermeasures, in order to improve the professional ability and comprehensive quality of accounting major students, conform to the market demand and the development of The Times.