A Digital-to-Time Converter based (DTC-based) fractional-N digital phase-locked loop (DPLL) using probability-density-shaping (PDS) spur immunity and quantization phase (Q-noise) reduction techniques is presented. PDS-DSM is used to generate a loop spur immunity control code for DTC. A diff type dither is proposed to further suppress the fractional spur. The loop nonlinearity will not cause fractional spurs if certain conditions are obeyed. Moreover, to reduce the quantization noise, a configurable Phase Interpolator (PI) with 0.125/0.25/0.5/1.0 division step is integrated with a multi-module divider (MMDIV), leading to an 18-dB Q-noise suppression. A reference doubler with duty-cycle correction is adopted to further reduce phase noise. The fractional spurs are greatly mitigated by combining the PDS-DSM and phase interpolator. A DPLL prototype using the aforementioned techniques was designed in a 40-nm standard CMOS process, occupying a 0.99 mm2 silicon area. At a near-integer-N frequency, i.e., near 2.23 GHz, with PDS turned on and off, the post-layout simulated fractional spur is −59 dBc and −20 dBc, respectively. The RMS jitter of the whole chip is 4.218 ps, corresponding to a figure of merit (FOM) of −220.5 dB.