This paper examines the economic independence of pesantren in Lombok, West Nusa Tenggara and its impact on the development of Micro, Small, and Medium Enterprises (MSMEs) surrounding pesantren. For this study, a descriptive quantitative research design was employed. The results are then shown as graphs, figures, and tables to facilitate their interpretation. There are 28 selected pesantren locations. 11 percent of pesantren are traditional, while 89 percent of pesantren are modern. Twenty of the 200 SME samples were discovered in the vicinity of the traditional salaf pesantren, while 180 were discovered in the vicinity of the modern pesantren. In this survey, the following criteria were developed for respondents: 1) responders who reside close to a mosque. 2) respondents who are employed by SMEs in the pesantren environment. The areas covered by the respondents of this study include Mataram City, Central Lombok Regency, and West Lombok Regency. This study revealed that pesantren that manage their finances and enterprises with a modern and independent attitude had a negligible effect on the growth of surrounding SMEs.