Peripheral Temperature Research Articles

Blood rheological and electrical properties and relationships with the microvascular tone regulation in patients with diabetes mellitus type 2

Aim. The study aims to evaluate impairment of the rheological and electrical properties of blood, plasma viscosity and blood conductivity in patients with type 2 diabetes mellitus (T2DM) in comparison with the data of the control group of healthy individuals. It also aims to investigate the changes of the skin blood flow responses to cold stress in T2DM patients through wavelet analysis of the peripheral skin temperature pulsations and to estimate their relationships with the blood viscosity and blood conductivity parameters, obtained from the simulation of experimental data with mathematical equations.Materials and methods. The whole blood viscosity was measured by Contraves LS30 viscometer (Switzerland) at a steady flow in 9 healthy individuals and in 13 patients with type 2 diabetes mellitus. Time variation of whole blood conductivity σ under transient flow at rectangular and trapezium shaped Couette viscometric flow and under electric field of 2 kHz was determined. The amplitudes of the skin temperature pulsations (ASTP) were monitored by «Microtest» device («FM-Diagnostics», Russia). To analyze the temperature fluctuations, wavelet transformation analysis of the low amplitude oscillations of skin temperature in accordance with myogenic (0.05–0.14 Hz), neurogenic (0.02–0.05 Hz), and endothelial (0.0095–0.02 Hz) control mechanisms of the vascular tone (WAST method) was applied.Results. Blood viscosity was increased in the T2DM patients’ group, while blood conductivity decreased in comparison to controls. Two sigmoidal equations were applied to describe the kinetics of blood conductivity. Both models include conductivity indices (σ1 , σ2 , σ3 ) and time indices too. The Pearson correlations between these parameters and the ASTP in the frequency ranges, corresponding to the myogenic, neurogenic and endothelial mechanisms of the microcirculation tone regulation were analyzed. The correlation analysis revealed good ASTP–(σ1 , σ2 , σ3 ) relationships in the neurogenic range 3 minutes after the cold test, while the ASTP–(σ1 , σ2 , σ3 ) correlation in the myogenic frequency range before the cold test was negative (r<–0.8, p<0.5).Conclusion. The results complement the studies of the microvascular regulatory mechanisms and endothelial dysfunction in patients with type 2 diabetes mellitus, as well as their relationships with the rheological and electrical properties of blood.

Psychophysiology during exposure to trauma memories: Comparative effects of virtual reality and imaginal exposure for posttraumatic stress disorder.

This investigation involved an in-depth examination of psychophysiological responses during exposure to the trauma memory across 10 sessions among active duty soldiers with combat-related posttraumatic stress disorder (PTSD) treated by Prolonged Exposure (PE) or Virtual Reality Exposure (VRE). We compared psychophysiological changes, session-by-session, between VRE and traditional imaginal exposure. Heart rate (HR), galvanic skin response (GSR), and peripheral skin temperature were collected every 5 min during exposure sessions with 61 combat veterans of Iraq/Afghanistan and compared to the PTSD Checklist (PCL-C) and Clinician-Administered PTSD Scale (CAPS) outcomes using multilevel modeling. Over the course of treatment, participants in the PE group had higher HR arousal compared to participants in the VRE group. With reference to GSR, in earlier sessions, participants demonstrated a within-session increase, whereas, in later sessions, participants showed a within-session habituation response. A significant interaction was found for GSR and treatment assignment for within-session change, within-person effect, predicting CAPS (d = 0.70) and PCL-C (d = 0.66) outcomes. Overall, these findings suggest that exposure to traumatic memories activates arousal across sessions, with GSR being most associated with reductions in PTSD symptoms for participants in the PE group.

Pain Caused by Ear Tagging in Kids of Native Black Goats

Purpose: The normal behavior of goat kids is influenced by painful husbandry procedures such as ear tagging, with kids reducing peripheral temperature and increase restlessness. The present study was designed to elucidate that pain caused by ear tagging affects peripheral temperatures and behavioral observations in Karadi kid goats. Study Design: Experimental Study Design. Subjects and Methods: Nineteen native black goat kids, aged 10-14 days, were used in this study as a sample. Eye and nasal temperatures were recorded before ear tagging process (control) and after ear tagging 5 times in 30 minutes. In addition, the behavior of each kid was observed for 30 minutes before and 30 minutes after ear tagging using focal sampling recorded with instantaneous time sampling to measure the duration and frequency of each behavior of the kids. Results: It was revealed that peripheral temperatures were significantly decreased for both eye (P<0.01) and ear (P<0.01) after ear tagging. The temperatures of both eye and ear increased directly after tagging and then decreased significantly (P<0.01) for 30 minutes. The proportion of time kid goats spent normal standing and suckling the dam’s teat decreased whereas the proportion of time spent head-shaking increased after tagging. In addition, abnormal standing was seen after ear tagging which was absent before the process of tagging. Significant differences were found between abnormal standing (P<0.01) and vocalization (P<0.01). While the differences between suckling, normal standing and head shaking were not significant. Conclusions: It is concluded that ear tagging causes considerable pain in kid goats.

Alprazolam-induced EEG spectral power changes in rhesus monkeys: a translational model for the evaluation of the behavioral effects of benzodiazepines.

Benzodiazepines induce electroencephalography (EEG) changes in rodents and humans that are associated with distinct behavioral effects and have been proposed as quantitative biomarkers for GABAA receptor modulation. Specifically, central EEG beta and occipital EEG delta activity have been associated with anxiolysis and sedation, respectively. The extent to which nonhuman primates show the same dose- and topography-dependent effects remained unknown. We aimed at establishing a nonhuman primate model for the evaluation of benzodiazepine EEG pharmacology. Four adult male rhesus monkeys were prepared with fully implantable telemetry devices that monitored activity, peripheral body temperature, and contained two EEG (central and occipital), one electromyography (EMG), and one electrooculography channel. We investigated daytime alprazolam-induced changes in EEG spectral power, sleep-wake states, EMG activity, locomotor activity, and body temperature. Alprazolam (0.01-1.8 mg/kg, i.m.) or vehicle was administered acutely, and telemetry recording was conducted for 1 h. Daytime alprazolam dose-dependently increased central EEG power (including beta activity), increased occipital EEG delta power, and decreased occipital EEG alpha, theta, and sigma power. There was an ~8-fold difference in the potency of alprazolam to increase central EEG beta vs. occipital EEG delta activity (based on relative EEG power). The highest dose, which increased both central EEG beta and occipital EEG delta relative power, induced sedative effects (increased time spent in N1 and N2 sleep stages) and decreased peripheral body temperature and locomotor activity. Alprazolam induces dose- and topography-dependent EEG changes in rhesus monkeys and provides a valuable model for studying benzodiazepine pharmacology.

Viscous dissipation and joule heating effects on forced convection power law fluid flow through annular duct

Here we numerically analyse the effects of viscous dissipation and Joule heating on forced convection heat transfer rate of electrically conducting magnetohydrodynamic, ( MHD) power law fluid flow through annular duct. Mathematical model is formulated for constant properties power law fluid with steady, incompressible and laminar fully developed flow assumptions. Heat transfer results are determined by taking constant heat flux with peripheral wall temperature “known as H1 thermal boundary condition” at the solid walls of the channel. It has been observed that the effect of viscous dissipation reduces due to enhance damping magnetic field effect by increasing the value of Hartman number, Ha, especially in the case of shear thickening fluids.

Effects of manipulating body temperature on sleep in postmenopausal women

Study objectivesA decline in sleep quality, slow wave sleep (SWS) and slow wave activity (SWA) are common in older adults. Prior studies have shown that manipulating body temperature during sleep can increase SWS/SWA. The aim of this study was to determine the effects of manipulation of body temperatures during sleep, using a high heat capacity mattress, on SWS/SWA and heart rate in post-menopausal women. MethodsTwenty-four healthy postmenopausal women between 40 and 75 years of age (mean age 62.4 ± 8.2 years, mean BMI 25.4 ± 3.5 kg/m2) were randomized in a single-blind, counterbalanced, cross-over manner to sleep on either a high heat capacity mattress (HHCM) or a low heat capacity mattress (LHCM) a week apart. Sleep was recorded using polysomnography during an 8-h sleep opportunity. Core and peripheral temperature were recorded using an ingestible capsule and thermochron respectively. ResultsIn comparison to the LHCM, sleep on HHCM exhibited a selective increase in SWS (average increase in Stage N3 of 9.6 min (2.1%), p = 0.04) and in slow oscillatory (SO) activity (0.5–1 Hz) in the first NREM/REM cycle (p = 0.04). In addition, the HHCM induced a greater reduction in core body temperature (p = 0.002). The reduction in core body temperature (first 180 min after lights out) from LHCM to HHCM was associated (r = 0.5, p = 0.012) with the increase in SO activity (SO cycle 1 and 2/cycle 3 and 4). Average heart rate was 1.6 beats/minute lower across the night on the HHCM compared to the LHCM (p = 0.001). ConclusionsThe results of this study indicate that manipulation of body temperature during sleep may be a useful approach to enhance SWS sleep in postmenopausal women.

Peripheral body temperature rhythm is associated with suicide risk in major depressive disorder: a case-control study

BackgroundPatients with major depressive disorder (MDD) may have an abnormal peripheral body temperature rhythm, but its relationship with suicidal risk and the response to treatment with antidepressants remain unknown.AimsThis study...

Underbody blankets have a higher heating effect than overbody blankets in lithotomy position endoscopic surgery under general anesthesia: a randomized trial.

BackgroundSurgery under general anesthesia results in temperature decrease due to the effect of anesthetics and peripheral vasodilation on thermoregulatory centers. Perioperative temperature control is therefore an issue of high importance. In this study, we aimed to compare the warming effect of underbody and overbody blankets in patients undergoing surgery in the lithotomy position under general anesthesia.MethodsFrom September 2018 to October 2019, 99 patients undergoing surgery for colorectal cancer in the lithotomy position were included in this randomized controlled trial and assigned to the intervention group (underbody blanket) or control group (overbody blanket).ResultsThe central temperature was significantly higher in the underbody blanket group than in the overbody blanket group at 90 min after the beginning of the surgery (p = 0.02); also in this group, the peripheral temperature was significantly higher 60 min after the beginning of the surgery (p = 0.02). Regarding postoperative factors, the underbody blanket group had a significantly lower frequency of postoperative shivering (p < 0.01) and a significantly shorter postoperative hospital stay (p = 0.04) than the overbody blanket group.ConclusionsWe recommend the use of underbody blankets for intraoperative temperature control in patients undergoing surgery in the lithotomy position under general anesthesia. Underbody blankets showed improved rise and maintenance of central and peripheral temperature, decreased the incidence of postoperative shivering, and shortened the postoperative length of hospital stay.

A novel rabbit fixator made of a thermoplastic mask for awake imaging experiments

This study aimed to develop and validate a novel rabbit fixator made from a thermoplastic mask for awake imaging experiments. When heated in a hot-water bath at 65–70 °C for 2–5 min, the thermoplastic mask became soft and could be molded to fit over the entire body of an anesthetized rabbit (4 ml of 3% pentobarbital sodium solution by intramuscular injection). Twenty rabbits were randomly divided into fixator (n = 10) and anesthesia (n = 10) groups. The animals’ vital signs, stress hormones (cortisol and adrenaline), and subjective image quality scores for the computed tomography (CT), positron emission tomography (PET), and magnetic resonance imaging (MRI) scanning were measured and compared. Phantom CT, MRI and PET studies were performed to assess the performance with and without the thermoplastic mask by using image agents at different concentrations or with different radioactivity. The respiration rate (RR), systolic blood pressure (SBP), diastolic blood pressure (DBP), peripheral capillary oxygen saturation (SpO2) and body temperature (T) decreased after anesthesia (all P < 0.05) but did not significantly decrease after fixation (all P > 0.05). The heart rate (HR), cortisol and adrenaline did not significantly decrease after either anesthesia or fixation (all P > 0.05). The subjective image quality scores for the CT and MRI images of the head, thorax, liver, kidney, intestines and pelvis and the subjective image quality scores for the PET images did not significantly differ between the two groups (all P > 0.05). For all examined organs except the muscle, 18F-FDG metabolism was lower after fixation than after anesthesia, and was almost identical of liver between two groups. The phantom study showed that the CT values, standard uptake values and MR T2 signal values did not differ significantly with or without the mask (all P > 0.05). A novel rabbit fixator created using a thermoplastic mask could be used to obtain high-quality images for different imaging modalities in an awake and near-physiological state.

Study on the decay characteristics and transmission risk of respiratory viruses on the surface of objects

The complex and changeable environment is a brand-new living condition for the viruses and pathogens released by the infected people to the indoor air or deposited on the surface of objects, which is an important external condition affecting the decay and transmission risk of the viruses. Exposure to contaminated surfaces is one of the main routes of respiratory diseases transmission. Therefore, it is very important for epidemic prevention and control to study the law of virus decay and the environmental coupling effect on various surfaces. Based on the analysis of the influencing mechanism, a large amount of experimental evidence on the survival of viruses on the surface of objects were excavated in this paper, and the effects of various factors, such as surface peripheral temperature, relative humidity, virus-containing droplet volume, surface materials and virus types, on the decay rate constants of viruses were comprehensively analyzed. It was found that although the experimental methods, virus types and experimental conditions varied widely in different experiments, the virus concentrations on the surface of objects all followed the exponential decay law, and the coupling effect of various factors was reflected in the decay rate constant k. Under different experimental conditions, k values ranged from 0.001 to 100 h−1, with a difference of 5 orders of magnitude, corresponding to the characteristic time t99 between 500 and 0.1 h when the virus concentration decreased by 99%. This indicates a large variation in the risk of virus transmission in different scenarios. By revealing the common law and individuality of the virus decay on the surface of objects, the essential relationship between the experimental observation phenomenon and virus decay was analyzed. This paper points out the huge difference in virus transmission risk on the surface at different time nodes, and discusses the prevention and control strategies to grasp the main contradictions in the different situations.

Temperature Field Variation Law of Low Exothermic Polymer Grouting Material in Repairing Void Damage of Frozen Soil Subgrade

In this study, the self‐developed grouting mold was used to study the heat release characteristics of different density polymer grouting material under different temperature conditions. The spatial distribution characteristics of the frozen soil subgrade temperature field under the effect of polymer grouting repair were analyzed. Further, the rules governing the temperature change of a frozen soil subgrade monitoring point under the effect of polymer grouting repair were studied. The heat transfer mechanism of polymer grouting material in frozen soil subgrade was revealed. The results showed that in the void region of the frozen soil subgrade, a discontinuity zone appeared in the temperature field distribution isotherm due to the effect of voids; this zone exhibited a layered radioactive distribution along the two sides of the void area. Furthermore, during the exothermic stage of the curing reaction, the temperature distribution isotherms changed from a layered radioactive distribution to a ring distribution that decreased from the inside to outside. During the natural cooling process, the peripheral temperature of the ring isotherm first decreased and a negative temperature ring‐shaped isotherm gradually formed. Finally, the upper boundary of the influence of the heat energy released by the curing reaction on the frozen soil subgrade temperature field was determined to be 30 cm, and the lower boundary was 20 cm.

Evaluación de un protocolo de prevención de la hipotermia durante anestesia general en perros domésticos sometidos a profilaxis dental

El incorrecto manejo térmico del paciente canino sometido a anestesia general puede generar complicaciones en la recuperación e inclusive presentar el riesgo de muerte. El objetivo fue evaluar un protocolo de prevención de la hipotermia en pacientes caninos sanos sometidos a anestesia general para la realización de un procedimiento de profilaxis dental. Para el método investigativo se reclutaron 10 pacientes para un ensayo clínico controlado de tipo cruzado por intención de tratamiento, a los pacientes se les sometió a dos procedimientos anestésicos, el primero sin ningún medio de mantenimiento de la normotermia, y el segundo procedimiento acompañado de un protocolo compuesto por precalentamiento durante 30 minutos a 28°C, manta reflectante Survival Blanket ® + luz radiante (foco infrarrojo de 250W) para minimizar la perdida de temperatura de los pacientes. Se evaluaron las temperaturas rectales (temperatura periférica) durante todo el perioperatorio (60 minutos) obtenidas en los 10 pacientes en ambas intervenciones, siendo estos datos analizados mediante una prueba estadística (T-Test) Como Resultados se encontró diferencias significativas entre aplicar y no aplicar dicho protocolo. Las diferencias estadísticamente significativas que se encontraron fueron: al final de la premedicación (p valor= 0.039), al inicio de la inducción (p valor = 0.041), y durante todo el mantenimiento (p valor= 0.008 – 0.013 – 0.012 – 0.005 – 0.008 – 0.005 – 0.005). Conclusiones. - se observó y demostró que combinar métodos activos y pasivos ayudan a minimizar la perdida de temperatura del paciente.

Feasibility of continuous fever monitoring using wearable devices

Elevated core temperature constitutes an important biomarker for COVID-19 infection; however, no standards currently exist to monitor fever using wearable peripheral temperature sensors. Evidence that sensors could be used to develop fever monitoring capabilities would enable large-scale health-monitoring research and provide high-temporal resolution data on fever responses across heterogeneous populations. We launched the TemPredict study in March of 2020 to capture continuous physiological data, including peripheral temperature, from a commercially available wearable device during the novel coronavirus pandemic. We coupled these data with symptom reports and COVID-19 diagnosis data. Here we report findings from the first 50 subjects who reported COVID-19 infections. These cases provide the first evidence that illness-associated elevations in peripheral temperature are observable using wearable devices and correlate with self-reported fever. Our analyses support the hypothesis that wearable sensors can detect illnesses in the absence of symptom recognition. Finally, these data support the hypothesis that prediction of illness onset is possible using continuously generated physiological data collected by wearable sensors. Our findings should encourage further research into the role of wearable sensors in public health efforts aimed at illness detection, and underscore the importance of integrating temperature sensors into commercially available wearables.

Mean core to peripheral temperature difference and mean lactate levels in first 6 hours of hospitalisation as two indicators of prognosis: an observational cohort study

BackgroundTo study mean core to peripheral temperature difference (CPTD) and the mean lactate levels over the first 6 h of admission to hospital, as indicators of prognosis in critically ill children.MethodsA prospective observational study in a tertiary level Pediatrics ICU in Delhi, India. Seventy eight paediatric patients from 1 month to 12 years were studied. Children with physical trauma, post-surgical patients and patients with peripheral vascular disease were excluded. Core temperature (skin over temporal artery) to peripheral temperature (big toe) difference was measured repeatedly every minute over 6 h and mean of temperature difference was calculated. Pediatric Risk of Mortality (PRISM) II, lactate clearance and mean lactate levels during that time were also studied. In-hospital mortality was used as the outcome measure.ResultsMean temperature differenceDuring the first 6 h after admission the mean temperature difference was 9.37 ± 2 °C in those who died and 3.71 ± 2.27 °C in those who survived (p < 0.0001). The area under the receiver operating curve (AUROC) was 0.953 (p < 0.0001). The comparable AUROC of PRISM II was 0.999 (p < 0.0001).Mean LactateMean lactate level in the first 6 h was 7.1 ± 2.02 mg/dl in those who died compared to 2.86 ± 0.87 mg/dl in those who survived (p < 0.0001). The AUROC curve for mean lactate was 0.989 (95% CI = 0.933 to 0.999; p < 0.0001). AUROC for the lactate clearance was 0.682 (p = 0.0214).ConclusionsThe mean core to peripheral temperature difference over the first 6 h is an easy-to-use and non-invasive method that is useful to predict mortality in children admitted to the Pediatric ICU. The mean lactate during the first 6 h of Pediatric ICU admission is a better index of prognosis than the lactate clearance over the same time period. They may be used as components of a scoring system to predict mortality.

Exercise mitigates sleep-loss-induced changes in glucose tolerance, mitochondrial function, sarcoplasmic protein synthesis, and diurnal rhythms

ObjectiveSleep loss has emerged as a risk factor for the development of impaired glucose tolerance. The mechanisms underpinning this observation are unknown; however, both mitochondrial dysfunction and circadian misalignment have been proposed. Because exercise improves glucose tolerance and mitochondrial function, and alters circadian rhythms, we investigated whether exercise may counteract the effects induced by inadequate sleep. MethodsTo minimize between-group differences of baseline characteristics, 24 healthy young males were allocated into one of the three experimental groups: a Normal Sleep (NS) group (8 h time in bed (TIB) per night, for five nights), a Sleep Restriction (SR) group (4 h TIB per night, for five nights), and a Sleep Restriction and Exercise group (SR+EX) (4 h TIB per night, for five nights and three high-intensity interval exercise (HIIE) sessions). Glucose tolerance, mitochondrial respiratory function, sarcoplasmic protein synthesis (SarcPS), and diurnal measures of peripheral skin temperature were assessed pre- and post-intervention. ResultsWe report that the SR group had reduced glucose tolerance post-intervention (mean change ± SD, P value, SR glucose AUC: 149 ± 115 A.U., P = 0.002), which was also associated with reductions in mitochondrial respiratory function (SR: -15.9 ± 12.4 pmol O2.s−1.mg−1, P = 0.001), a lower rate of SarcPS (FSR%/day SR: 1.11 ± 0.25%, P < 0.001), and reduced amplitude of diurnal rhythms. These effects were not observed when incorporating three sessions of HIIE during this period (SR+EX: glucose AUC 67 ± 57, P = 0.239, mitochondrial respiratory function: 0.6 ± 11.8 pmol O2.s−1.mg−1, P = 0.997, and SarcPS (FSR%/day): 1.77 ± 0.22%, P = 0.971). ConclusionsA five-night period of sleep restriction leads to reductions in mitochondrial respiratory function, SarcPS, and amplitude of skin temperature diurnal rhythms, with a concurrent reduction in glucose tolerance. We provide novel data demonstrating that these same detrimental effects are not observed when HIIE is performed during the period of sleep restriction. These data therefore provide evidence in support of the use of HIIE as an intervention to mitigate the detrimental physiological effects of sleep loss.

Effects of local cold application on tissue & peripheral oxygen saturation, peripheral blood flow, skin temperature, and body temperature of healthy adult

Effects of local cold application on tissue & peripheral oxygen saturation, peripheral blood flow, skin temperature, and body temperature of healthy adult

Changes of Peripheral Nerve Function and Vitamin B12 Level in People With Parkinson's Disease.

Background and Purpose: Peripheral nerve function plays an important role in balance control. Impairment of peripheral sensory information appears in people with Parkinson's disease (PD). Furthermore, there is a link between peripheral nerve disorders and vitamin B12 level. Here, we studied whether there were deficits of peripheral nerve function and vitamin B12 level, which may lead to decreased postural stability in PD.Methods: Fifty PD and 50 age-matched healthy subjects were enrolled in the study. This study evaluated folic acid and vitamin B12 levels in serum. Postural balance was studied according to the clinical Tinetti scale. Some comprehensive physiological assessments of peripheral nerve functions, including peripheral sensation, the perception of temperature, pain, and touch sensations, were also undertaken in this study.Results: Compared with the control group, vitamin B12 and folic acid were decreased in PD (P < 0.05). Furthermore, the PD group exhibited declines in peripheral nerve functions, including touch, temperature, pain, and nerve conduction velocity (P < 0.05). Statistical tests identified a significant association between decreased peripheral nerve function and poor balance according to the Tinetti scale (P < 0.05). Low vitamin B12 levels were also associated with deficits of peripheral nerve function, cumulative levodopa dose, and poor balance in PD (P < 0.05).Conclusions: Data suggested that peripheral nerve function was impaired in people with PD. Deficits of sensory input and low vitamin B12 level may contribute to balance deficits in PD.

The effect of chronotype and time of assessment on cognitive performance

ABSTRACT Standard cognitive measures are often applied at various times of the day to assess cognitive deficits in patients with neuropsychiatric and neurodegenerative disorders, irrespective of their chronotype. In this study, we aimed to determine whether the subjectively nonpreferred time of an assessment might be a crucial factor in persons with extreme chronotypes. We compared morning (08:00) and evening (20:00) cognitive performance in extreme morning, extreme evening, and intermediate chronotypes determined by the Morningness-Eveningness Questionnaire, supported by actigraphy and peripheral temperature measurement. The assessment sessions were performed in pseudorandom order over two consecutive weekend days. We administered the commonly used test battery for neurocognitive assessment comprised of tasks aimed mainly at attention, processing speed, working memory, and declarative memory. The time of assessment influenced the declarative memory measures, whereas the chronotype-specific differences occurred only in the Stroop colour-naming subtest aimed at processing speed. The observed effects should be considered in routine clinical practice because they might cause misrepresentation of the results obtained during improperly timed cognitive assessment. Our results also point towards similarity of doves and owls in contrast to larks in cognitive performance, suggesting that early morning assessments should also be considered in cases of intermediate chronotypes.

Terapia cognitivo-conductual grupal sobre la sintomatología depresiva-ansiosa y temperatura nasal en mujeres con cáncer de mama: Estudio piloto

Objetivo. Evaluar el efecto de una intervención cognitivo-conductual grupal sobre la sintomatología ansiosa-depresiva y el funcionamiento autonómico afectivo en mujeres con cáncer de mama. Método. Estudio pre-experimental con una muestra de 17 mujeres mexicanas con un nivel de depresión de moderada-severa y diagnóstico de cáncer de mama. Los instrumentos de evaluación fueron el Inventario de Depresión de Beck y la Escala de ansiedad de Hamilton; además de una evaluación del funcionamiento autonómico mediante el registro intra-sesión de la temperatura periférica nasal. Resultados. Se observó una reducción de los síntomas de depresión (Z=-3.182, p=0.001), ansiedad (Z=-2.697, p=0.007) y un incremento de la temperatura al finalizar el tratamiento (Z=-2.669, p=008) que se mantuvo por seis meses (Z=-3.266, p=0.001). Conclusión. La terapia cognitivo conductual grupal fue eficaz para la reducción de la sintomatología ansiosa-depresiva y la regulación autonómica en el grupo de mujeres con cáncer de mama.

Patch validation: an observational study protocol for the evaluation of a multisignal wearable sensor in patients during anaesthesia and in the postanaesthesia care unit

IntroductionExcept for operating rooms, postanaesthesia care units and intensive care units, where the monitoring of vital signs is continuous, intermittent care is standard practice. However, at a time when only...