Sexual Performance Research Articles

Comparison of Bisexual and Genetic Strains of Ceratitis capitata from Various Origins

Background: The sterile insect technique (SIT) of Mediterranean fruit fly Ceratitis capitata depends on the ability of male to compete successfully against wild male in obtaining matings with wild females. Methods: To evaluate mass and wild reared the sexual performance and compatibility of medflies has been conducted in a series of field cages test. At the same time, this study has been done in the laboratory domestication as well. Three populations have been tested in this research: wild flies from of Perth Hills stone; Western Australia and Norwood road, Maida Vale, Perth; semi-wild flies after 7 to 10 generation in the lab. and a mass-reared and wild strains of flies were used in the study. Result: All the field cages have been indicating that all population of medfly are all most the same. There is no significant difference in the number of egg and sex ratio of wild population. In the mass- reared males, the performed of males are significantly poorer than wild male in achieve mating with wild female. The study has been showed that mating performances are reduced in mass-reared and semi-wild fly after 8 to 11 generation in laboratory.

Crip slutaesthetics: Erotic object choreographies and temporal fractures in burlesque

Direct, communicative and largely accessible, the choreographic tools of nightlife performance often elicit dramatic reactions from spectators, whether sexy, funny, surprising, glamorous or all of the above. This article follows pleasure, joy, erotics and pain across crip slutaesthetics into the choreographies of crip nightlife, based on interviews with four burlesque artists based in the United States with diverse experiences of sickness, neurodivergence, trauma and disability. I use movement analysis alongside attention to other artistic practices foundational to burlesque such as prop and costume creation to unravel the ways that performers Sweet Lorraine, Poison Ivory, Chaos X Machina and Jaqueline Boxx integrate their divergent bodymind experiences into compelling aesthetics and justice-oriented frames. I argue that crip slutaesthetics, that is the aesthetic qualities of crip sexual performance, can offer tools towards undoing ableism as it is entangled with racism, homophobia and transphobia that are often silenced by more formal concert dance worlds in the effort to deny embodied difference as well as pleasure from the proscenium stage.

Development and psychometric properties of an instrument to measure perception of aphrodisiac use among undergraduates in a southwestern Nigerian university.

A tool to measure perception of aphrodisiac use by undergraduates students of University of Ibadan, Oyo State, Nigeria was developed and validated. The study was hinged on several theories that could explain potential to use aphrodisiac among the youths. An exploratory mixed methods design was used to develop a scale to measure perception of aphrodisiac use by undergraduate students of University of Ibadan. Qualitative data collection was performed among thirty equally represented male and female students and five key informant interview participants while 919 participants completed the quantitative phase (surveys). Integration of matched qualitative themes from FGD/KII to survey domains was achieved through the 'building approach'. Qualitative themes assessing perceptions of aphrodisiac use by university undergraduate students were used to develop original survey items as well as new survey items peculiar to research subjects. Exploratory factor analysis was deployed on polychoric correlation matrix of the items using R-statistical packages. Further model fit analysis was conducted using confirmatory factor analysis on the items suggested by EFA as well as composite reliability and construct validity tests for the constructs. Mean Z-scores of factors were computed against socio-demographics and symptoms of aphrodisiac use among respondents that have ever used it. Most respondents (84.3%) were under 25 years, mostly male (58.4%) and singles (96.3%), with 41.3% earning ≤20,000 naira monthly. The enhanced content validity of the items from mixed method analysis yielded two major domains. Two succession of factor analyses and a structural equation modeling suggested that a first-order model is good fit for experimental data (TLI = 0.931; CFI = 0.948; SRMR = 0.047; RMSEA = 0.083). The four-factor solution to the model included: prolonged sexual performance, use without erectile dysfunction or medical advice, treatment of erectile dysfunction and recreational purposes with an internal and composite reliability that ranged from 0.62-0.92 and 0.63-0.92. The validation with socio-demographics and consequences of aphrodisiac use indicated that: Male respondents, those older than 20years, the married, those from poorly educated parent and sufferers of all related consequences had statistically significant differences with poor perception of aphrodisiac use' domains. This validated instrument is good for assessment of perception of aphrodisiac use among students in tertiary institution albeit with caution. A version of the scale that is broadened with highly refined items and tested for high internal validity is suggested.

Qualitative exploration of sexual dysfunction and associated coping strategies among Iranian prostate cancer survivors.

Our understanding of the experiences of prostate cancer survivors regarding their sexual life and related issues remains limited. Therefore, this study aimed to explore sexual dysfunction and associated coping strategies among Iranian prostate cancer survivors. A qualitative study was undertaken. Participants were 15 Iranian prostate cancer survivors chosen using purposeful sampling. Data collection involved conducting in-depth semi-structured interviews, followed by the utilization of the conventional qualitative content analysis method for data analysis. Three themes were developed: (a) suspension of sexual life-treatment for prostate cancer significantly impacted participants' sexual lives; (b) emotional resilience and psychological coping strategies-various psychological strategies were used to tackle sexual dysfunction; (c) efforts to regain sexual function-several strategies were applied to enhance sexual performance. Our study findings provide insights into the experiences of prostate cancer survivors and subsequent shifts in their sexual dynamics and coping with the disease. Healthcare providers should actively identify patients' concerns and develop culturally tailored care strategies to address sexual challenges and improve coping among prostate cancer survivors.

Social Perceptions of Masculinity and Sexual Esteem Are Impacted by Viagra Use, Testosterone, and Sexual Performance.

Sexual behaviors play a role in the social construction of masculinity. Moreover, this stereotype has been capitalized upon by pharmaceutical companies, as well as those that sell products not approved by the U.S. Food and Drug Administration, for purposes of marketing sexual medicines. Stereotypical notions of masculinity, however, also emphasize the importance of self-reliance, which may cause some to look unfavorably upon the use of sexual medicine. Consistent with this notion, a male target was viewed as more masculine when his female partner consistently reached orgasm, unless he had no history of erectile dysfunction (ED), but was taking Viagra anyway (Experiment 1; N = 522). In addition, when his partner consistently reached orgasm, ratings of his sexual esteem were also lower if he used Viagra than if he did not, but only if he had no history of ED. In Experiment 2 (N = 711), although there was no effect of a male target's use of testosterone, social perception of his masculinity and sexual esteem increased as his "natural" levels of testosterone increased. In addition, exploratory analysis revealed that if the male target had low (but not normal or high) "natural" levels of testosterone, ratings of his masculinity were higher if his female partner consistently had an orgasm, which suggests that female orgasm served to "rescue" masculinity. Because expectations about drugs drive their use, it is important to address preconceived notions about the use of sexual medicines for purposes of enhancing masculinity and sexual esteem, as the social perception of their use is much more complex.

Clarifying Perceived Priorities of Reproductive Health Concerns in Diabetic Women

Background and Objective: Women with diabetes often have concerns regarding their reproductive health and sexual well-being. These concerns represent all the important issues that affect the health of the reproductive system and its function, which can also affect the general and social health of the person. Therefore, the present study aimed to explain the reproductive health concerns of women with type 1 diabetes under treatment at Hami and Khazarian Clinic in Hamadan, Iran. Materials and Methods: The present research was conducted using the exploratory qualitative method. An in-depth unstructured interview was carried out with 17 married women aged 20-45 years with type 1 diabetes, and the data collected was analyzed using the constant comparison method. Results: The main themes obtained were sexual performance and satisfaction with six subcategories, including physical, psychological, social, reproductive, supportive, and informational, as well as the marital dimension (sexual performance, marital satisfaction). Conclusion: Since diabetes at younger ages is spreading rapidly and this problem affects the quality of marital and sexual life, the need to identify the perceived priorities of reproductive health concerns and design necessary interventions is felt.

(148) SINGLE MEN’S SEXUAL HEALTH DURING THE COVID 19 PANDEMIC

Abstract Introduction COVID-19, characterized by the World Health Organization as a pandemic [1], has affected human beings as a whole. Social isolation has led to feelings of fear, anxiety and panic, and can cause even more serious effects such as depression and sexual dysfunction. Over the last year, several studies have been carried out around the world seeking to understand the impacts of the pandemic on sexual issues, however, the majority of these studies focus on women or changes in sexual behavior in couples, with little data on the single male population. Objective The present study aims to analyze the impacts of the pandemic on sexual function, quality and desire in single men. Methods 177 Brazilian men were included, cisgender, over 18 years old, single and who had started their sexual life. 73 participants were excluded if they filled out the questionnaire incompletely, were not cisgender or had not initiated sexual activity. Two questionnaires were used: the Sexual Quotient - Male Version, developed and validated in Brazil by Abdo in 2006 and one authored by himself - given the scarcity of validated tools in the proposed context. The first contains 10 items that assess physical and emotional aspects of the sexual experience (confidence, quality of foreplay, satisfaction with the partnership, quality of erection, ejaculatory control, ability to reach orgasm and satisfaction with sexual intercourse). The second includes questions that investigate the frequency of sexual relations, number of partners, level of satisfaction and sexual performance, frequency of masturbation, access to pornography and dating apps. Results Up to 33% of participants stated that they had difficulty, at least half of the time, keeping their penis erect. 29.93% said they had difficulty having a sufficiently rigid erection at least half of the time. Furthermore, 41.80% feel discouraged, at least half of the time, from wanting sex again due to their sexual performance. 59% said they were heterosexual. Of the various data obtained, some had a greater impact on men’s sexual life. The most prevalent factor was the increase in self-masturbation, a characteristic that correlates with the increased use of technology to maintain an active sex life and dating apps. Furthermore, unlike international research [2, 3], premature ejaculation was reported more by participants than erectile dysfunction. Regarding sexual activities, the majority of participants reported not having reduced their frequency, even with sexual dysfunctions and increased self-masturbation. This data is even more intriguing when we consider that 2/5 of the participants did not feel encouraged to perform sexual activity again due to their previous performance. Conclusions Single men’s sexual health during the COVID-19 pandemic has changed in both interpersonal and individual aspects. Furthermore, technology was, in the sexual sphere, an escape for those deprived of social relationships, becoming essential in the routine of the individual in quarantine. Disclosure No.

(035) USE OF BREMELANOTIDE IN MEN WITH SEXUAL DYSFUNCTION AT A SEXUAL MEDICINE CLINIC

Abstract Introduction Bremelanotide (Vyleesi), a non-hormonally based CNS medication, was FDA approved for premenopausal women with generalized, acquired hypoactive sexual desire disorder (HSDD) in 2019. It modulates central dopaminergic pathways involved in sexual desire, arousal and orgasm and is reported to increase genital blood flow in women and men within hours of subcutaneous administration. Our clinic has been prescribing bremelanotide off-label to men with sexual dysfunctions (SD) since its approval. Objective To better understand the use of bremelanotide prescribed to men who underwent a biopsychosocial evaluation in our clinic, we evaluated prescribing patterns, improvements in sexual function, overall satisfaction, and side effects. Methods Bremelanotide prescription dispensing data from our facility was compiled September 2019 through June 2023 and analyzed for prescribing patterns and refill rates for all patients. A one-group study design interview trial of men with SD prescribed bremelanotide was performed. After signing consent, participants answered the Quality of Life Dimension of Sexual Quality of Life Questionnaire, Patient Global Impression of Improvement (PGI-I) and General Assessment Questions. After answering questionnaires online, participants completed a structured interview on the telephone with a single interviewer. Descriptive statistics characterized the study cohort. Adverse events were collected. Results Over the 46-month period, bremelanotide has been dispensed to men for SD 444 times; 65% of dispenses were refills. In comparison, during that same time period, the medication was prescribed 76 times to premenopausal women with 29% refills, and 104 times to postmenopausal women with 52% being refills. Over a recent 18 period, refill rates have been 73% (n = 219) for men, in contrast to 47% for premenopausal women (n = 30), 52% for postmenopausal women (n = 29). These data resulted in an interest in learning more about the experiences of the men using bremelanotide for HSDD and other SD. At the time of this interim analysis, 23 men signed consent and 22 completed online questionnaires. 76% of these men were more satisfied with their lovemaking and duration of lovemaking; 83% reported vaginal insertion was easier and 65% said it was easier to orgasm. Concerning feelings about initiating lovemaking, 76% were more at ease and 75% anticipated it would be more pleasurable and 71% more carefree. 56% believed orgasm was more pleasurable and 65% said that lovemaking was more pleasurable while 71% reported that the partner’s overall experience was more pleasurable. Using the PGI-I, 70% of participants felt that sexual function after using bremelanotide was a little better, much better, or very much better. The interview revealed that in men for whom bremelanotide worked, they had improvement in HSDD (39%), erectile dysfunction (52%), orgasm (17%), and anxiety about sexual performance (39%). Side effects included nausea (30%), flushing (22%), headache (13%), bothersome spontaneous erections without sexual stimulation for about 24 hours after injection (13%), and incontinence, cramping and abdominal burning (4% each). All adverse events were transient. Conclusions In our clinic, men prescribed centrally-acting bremelanotide off-label for SD filled and refilled their prescriptions more often than women. Our study showed that bremelanotide safely and effectively improved multiple SDs for some men. Disclosure Yes, this is sponsored by industry/sponsor: Palatin. Clarification: Industry funding only - investigator initiated and executed study. Any of the authors act as a consultant, employee or shareholder of an industry for: TRT, MTS.

(309) CASE REPORT: SEXUAL COGNITIVE THERAPY FOR PATIENTS DIAGNOSED WITH ERECTILE DYSFUNCTION ASSOCIATED WITH OBSESSIVE COMPULSIVE DISORDER

Abstract Introduction Erectile Dysfunction (ED) and Obsessive Compulsive Disorder (OCD) can significantly impair an individual’s quality of life, affecting sexual functioning and mental health. Understanding the interplay between these conditions is essential for developing effective therapeutic interventions. Objective To report the efficacy of Sexual Cognitive Therapy in treating a patient with comorbid ED and OCD. Methods Case Presentation: A 20-year-old cisgender heterosexual male presented with difficulties in achieving and maintaining an erection, feelings of failure in sexual and academic domains, and anxious symptoms. The patient had a family history of OCD and generalized anxiety disorder. Initial diagnostic hypotheses included erectile dysfunction and anxious symptoms, later confirmed as OCD and ED. Intervention: The intervention comprised cognitive-behavioral techniques and specific sexual therapy strategies, including psychoeducation on sexual myths and the sexual response cycle, cognitive restructuring, mindful sex practices, and sensory focus exercises. The therapy aimed to identify and modify dysfunctional thoughts, beliefs, and behaviors contributing to sexual problems. Results Results: The patient exhibited significant improvement in cognitive flexibility, a reduction in OCD and ED symptoms, and increased confidence in sexual performance. He transitioned from reliance on medication (Viagra) to successful sexual activity without it. The intervention effectively addressed underlying cognitive distortions and sexual myths, contributing to overall symptom reduction and partial remission of OCD. Conclusions Conclusions: This case report demonstrates that Sexual Cognitive Therapy can effectively manage the complex relationship between ED and OCD. The patient’s progress highlights the potential of a tailored, integrative therapeutic approach for treating comorbid sexual and mental health disorders. Further studies are warranted to validate these findings and refine therapeutic strategies for similar cases. Disclosure No.

(111) SAFETY OF AN ELASTOMER-BASED HOOK-AND-LOOP CONFIGURATION “SMART” PENILE CONSTRICTION DEVICE WORN OVERNIGHT AKA: IS IT OK TO FALL ASLEEP WITH THIS COCKRING?

Abstract Introduction Penile constriction devices are commonly used for the management of erectile dysfunction, climacturia, and general sexual performance enhancement, as a stand-alone or multimodal therapy. One common concern is that prolonged utilization of a penile constriction device can lead to difficulty with device removal, penile injury, and potentially penile necrosis. Objective With traditional penile constriction devices, there is no way to objectively monitor safety or aggregate user experience data. We hypothesize that a novel elastomer based hook-and-loop configuration cock ring is safe for use overnight, and that biometric sensors embedded in the device can document spontaneous nocturnal erections- thereby confirming presence of blood flow to the penis hours into wear. Methods A novel elastomer-based hook-and-loop configuration penile constriction device with embedded pressure sensors was worn by participants in a home environment. Recordings of erection rigidity and duration were uploaded to participants’ smart-phone app via Bluetooth, and data was centrally aggregated by the app engineering team. Subjective reports of user experience were aggregated via narrative input. Results 5204 unique recordings were obtained over a 14 month period. Mean duration of recording was 6.57+/-3.92 hours. 2700 recordings were greater than 4 hours in duration, with an average 3.09+/-1.62 erections per recording. There were no reports of priapism or dermatitis reported across all users. Two users noted discomfort after >4 hours of use, but they were able to release the device without difficulty. Conclusions A biometric sensor enabled “smart” cockring, composed of elastomer in a novel hook-and-loop configuration was worn >5000 individual times with an average duration of >6 hours of wear. There were no significant adverse events, and multiple erections were documented for users who kept the device on for >4 hours, indicating physiologic blood flow to the penis. To our knowledge, this is the first penile constriction device to have proven safety with overnight use. Disclosure Yes, this is sponsored by industry/sponsor: FirmTech. Clarification: Industry initiated, executed and funded study. Any of the authors act as a consultant, employee or shareholder of an industry for: FirmTech.

(265) PSYCHOLOGICAL FACTORS RESULTING FROM SEXUAL DYSFUNCTION IN MEN IN BRAZIL: HOW DEEP DOES THIS GO?

Abstract Introduction Men’s sexual health in Brazil faces challenges, especially due to the psychological impact of sexual dysfunctions. Historically, sexual function has been pivotal in men’s lives, both biologically and in terms of psychological well-being. However, there is still a reluctance to seek help for sexual health issues, evidenced by the lower frequency of male medical consultations compared to female’s. This context underscores the need to understand the impact of these dysfunctions on the mental quality of life of Brazilian men. Objective This study aims to comprehend the impact of male sexual dysfunctions on the mental quality of life of men in Brazil, utilizing a multidisciplinary approach that incorporates local statistical data and a review of Brazilian articles on the subject. Additionally, it seeks to provide insights for healthcare professionals working in this field, aiming to improve both the physical and mental treatment of men with sexual dysfunctions. Methods The methodology employed was literature research, using recognized databases such as the Virtual Health Library, Scientific Electronic Library Online (SCIELO), Latin American and Caribbean Literature in Health Sciences (LILACS), BIREME, and Google Scholar. Specific descriptors related to male sexual dysfunctions, such as “erectile dysfunction” and “premature ejaculation,” were used. Inclusion criteria were applied, considering the relevance of articles to the topic at hand, and ethical criteria were observed throughout the review process. Results The results of this review reveal a range of Brazilian studies on male sexual dysfunctions, addressing both the physical and psychological aspects of these conditions. Most studies focus on specific dysfunctions such as erectile dysfunction and premature ejaculation, highlighting the interconnection between these issues and concerns such as anxiety, depression, and self-esteem. Additionally, research gaps were identified, emphasizing the need for more studies exploring integrated therapeutic interventions and addressing the needs of specific populations of Brazilian men. Conclusions The Brazilian Sexual Behavior Study (ECOS), conducted with the Brazilian population, revealed that 46.2% of men in the country face erection difficulties at different levels, with the incidence of complete erectile dysfunction tending to increase with age. Research indicates that men with sexual dysfunction exhibit high levels of anxiety, tension, and negative feelings, anticipating unsatisfactory sexual performance. On the other hand, individuals with sexual dysfunction direct their attention to concerns related to performance and negative past sexual experiences, which hinders their ability to focus on erotic stimuli and decreases their sexual response. This study emphasized the importance of an integrative approach in understanding and treating male sexual dysfunctions in Brazil. In conclusion, the findings highlighted the need for greater awareness of male sexual health and public policies that promote equitable access to sexual health services. Additionally, it is suggested that future research focus on developing more effective therapeutic interventions and addressing the mental health needs of Brazilian men. It is understood that this study has contributed to advancing knowledge about male sexual health and highlighted key areas for future investigation and intervention. Disclosure No.

Novel emerging therapy for erectile dysfunction: efficacy and safety of flat magnetic stimulation.

The erectile dysfunction (ED), which is the inability to achieve and/or sustain a penile erection sufficient to result in a satisfying sexual performance, represents a very common complaint. for men over forty years old. The aim of the study was to evaluate if Flat Magnetic Stimulation (FMS) technology could help individuals with symptomatic erectile dysfunction. Twenty patients with erectile dysfunction, underwent eight sessions of about 30 minutes each in a twice a week frequency with the study device. During treatments, every potential side effect was assessed. The International Index of Erectile Function (IIEF) was compiled by all patients at the beginning, after the eighth treatment and at 1 month from the end of the last treatment. The questionnaire scores were presented as median values along with the interquartile range (IQR) and we set the significance threshold at 0.01. After the treatment and at 1-month follow-up, the increase in questionnaire scores was statistically significant compared to the baseline, thus supporting the clinical usefulness of this treatment. In particular, the result of the study indicates a statistically significant difference between IIEF score before treatment (Median = 34) and IIEF score after the end of treatment (Median = 45) and between IIEF score before treatment and IIEF score at 1-month follow-up (Median = 54). The study findings showed that FMS represents a promising treatment option to individuals affected by symptomatic erectile dysfunction.

Unveiling Multidimensional Meanings: A Critical Analysis of Jungkook's "3D" Lyrics Using Fairclough's CDA Theory and Butler's Sexual Performativity Theory

This article offers a in depth study of the lyrics of BTS's song "3D," employing Judith Butler's theory of gender performativity and Norman Fairclough's Critical Discourse Analysis as the research’s approaches. The study investigates how the song deviates from traditional masculine narratives by integrating components of worry and compassion into its portrayal of masculinity, offering an alternative conceptual framework for understanding gender roles. The findings highlight the role of the song in both support and questioning established gender standards, so illustrating the significant influence of media on the formation of masculinity. This study is limited to single song lyrics. It is necessary for further exploration into the portrayal of gender in media through diverse methodologies and active engagement with fan perspectives. This piece holds significant academic value as it contributes to the understanding of gender portrayal in media and its impact on societal gender norms.

INVESTIGATING THE EFFECTS OF PAUSINYSTALIA YOHIMBE AQUEOUS LEAVES EXTRACT ON PARAMETERS FOR REPRODUCTIVE PERFORMANCE IN EXPERIMENTAL RATS

ABSTRACT BACKGROUND: Herbal plants and herbal preparations are widely used as immunomodulatory medicines that helps in improving reproductive health in humankind, and they are globally used and have rapidly grown in economic developmental importance. OBJECTIVE: The study was conducted to investigate the effects of the aqueous extract of P. yohimbe leaves on sexual reproductive performance in Wistar rats. The primary outcome of the study is the reproductive performance sexual rate. METHODS: The experimental study was carried out on albino rats of the Wistar strain, weighing between 150 and 200g sexually naive. The animals were raised in polyethylene cages and divided into four groups, which received a saline solution (control group), 2, 5, and 10 mL/kg of the aqueous extract of P. yohimbe leaves for fourteen days orally. The sexual behavior test was performed according to three types of crossing. RESULTS: The results of the treated groups showed a significant increase in mating frequency compared to the control group. Overall, the results showed that P. yohimbe significantly affects sexual behavior. The aqueous extract of P. yohimbe leaves increased sexual behaviour and orientation activity performance recorded in the treated rats. CONCLUSION AND RECOMMENDATION: The enhanced reproductive performance appetitive detected in the study, justify the indigenous use of the herbal plant in reproductive medicine and could be a precursor in the synthesis of useful drugs. However, based on the current findings, we recommend that careful administration be considered as a better option justifying human circumstances for patient with advanced mankind age in low dosage resource settings, as it achieves a better reproductive performance rate at a lower dose dependent increase.

Trends, safety, and efficacy of wearable male sexual devices.

The prevalence of male sexual dysfunction (MSD) increases with age, with >50% of men aged >40years reporting erectile dysfunction (ED). In recent years, wearable male sex devices (WMSDs) have been increasingly utilized by patients and recommended by sexual medicine clinicians. This study seeks to investigate the safety and efficacy of products currently marketed for the treatment of MSD. Available products for WMSDs were reviewed by analyzing product websites, forums, advertisements, and clinical recommendations. Qualitative comparisons were based on patient reviews, cost, and specific features. Investigatory evidence and Food and Drug Administration status were also reviewed. Additionally, Google Trends was used to determine the popularity of devices over time. Eight WMSDs for the treatment of MSD and enhancement of sexual pleasure were reviewed. Constriction bands, such as the Maintain Ring Loop, Eddie by Giddy, and Xialla, have shown significant benefits in clinical trials and were the most popular devices among patients. Smart devices can provide real-time feedback on erectile quality and/or sexual performance. Similar to the RigiScan, the Adam sensor provides feedback on erectile quality while monitoring changes in penile tumescence during sleep with additional analysis available through a mobile application. Neuromodulation devices such as the Morari Patch and vPatch/in2 Patch use electrical stimulation to delay ejaculation and improve sexual function. The FirmTech Performance Ring uses sensors to track the vital signs of erectile fitness with clinical trials ongoing. Overall, this review describes the available investigatory evidence for a range of WMSDs and highlights the potential benefits and limitations of these devices in treating MSD and enhancing sexual pleasure. Further research is needed to evaluate the effectiveness of these devices and to determine which ones may be the most suitable for individual patients.

Stress during pubertal development affects female sociosexual behavior in mice

Puberty is a crucial phase for the development of female sexual behavior. Growing evidence suggests that stress during this period may interfere with the development of sexual behavior. However, the neural circuits involved in this alteration remain elusive. Here, we demonstrated in mice that pubertal stress permanently disrupted sexual performance without affecting sexual preference. This was associated with a reduced expression and activation of neuronal nitric oxide synthase (nNOS) in the ventrolateral part of the ventromedial hypothalamus (VMHvl). Fiber photometry revealed that VMHvl nNOS neurons are strongly responsive to male olfactory cues with this activation being substantially reduced in pubertally stressed females. Finally, treatment with a NO donor partially restored sexual performance in pubertally stressed females. This study provides insights into the involvement of VMHvl nNOS in the processing of olfactory cues important for the expression of female sexual behavior. In addition, exposure to stress during puberty disrupts the integration of male olfactory cues leading to reduced sexual behavior.

Effects of Dermal Fillers on Vaginal Laxity and Female Sexual Function: A Minimally Invasive Procedure for Vaginal Rejuvenation

Introduction: For improving vaginal rejuvenation and minimizing vaginal laxity, the increased demand for soft tissue fillers may give females seeking such therapies the chance to have better general health and sexual performance. To address a wider range of female health issues, and support a more all-encompassing approach to personal wellbeing as cosmetic treatments improve, it is crucial to research the possible repercussions of these minimally invasive operations. Methodology: The strength of pelvic floor muscles was measured using the Laborie Peritron 9300 (Portsmouth, New Hampshire, USA) perineometer. A 110 mm long conical vaginal probe with a 26 mm diameter, that may extend to 33 mm under pressure, is a characteristic of this device. The vaginal probe is connected to the perineometer’s main body by an 80 cm plastic tubing. When the probe is squeezed, the gadget has a pressure sensor that tracks vaginal pressure. A silicone rubber sensor loaded with air is included into the probe itself, to detect pressure in cmH2O. The Female Sexual Distress Scale-Revised (FSDS-R) was used to measure the participants’ degrees of sexual distress, and this method made it easier to gauge the participants’ pelvic floor muscle strength. Results: The participants’ mean age was 39.43±2.12 years, and further demographic characteristics provided evidence that 44% of the participants were married for 10 years and had children; 36% were married for 5 years with no children; and 20% had been married for less than 5 years. Conclusion: Soft tissue fillers, which have shown a rise in popularity, are a viable means of resolving issues with vaginal elasticity and rejuvenation.

Sexual conflict and social networks in bed bugs: effects of social experience.

Living in groups can provide essential experience that improves sexual performance and reproductive success. While the effects of social experience have drawn considerable scientific interest, commonly used behavioral assays often do not capture the dynamic nature of interactions within a social group. Here, we conducted 3 experiments using a social network framework to test whether social experience during early adulthood improves the sexual competence of bed bugs (Cimex lectularius) when placed in a complex and competitive group environment. In each experiment, we observed replicate groups of bed bugs comprising previously socialized and previously isolated individuals of the same sex, along with an equal number of standardized individuals of the opposite sex. Regardless of whether we controlled for their insemination history, previously isolated males mounted and inseminated females at significantly higher rates than previously socialized males. However, we found no evidence of social experience influencing our other measures of sexual competence: proportion of mounts directed at females, ability to overcome female resistance, and strength of opposite-sex social associations. We similarly did not detect effects of social experience on our female sexual competence metrics: propensity to avoid mounts, rate of successfully avoiding mounts, opposite-sex social association strength, and rate of receiving inseminations. Our findings indicate that early social experience does not improve sexual competence in male and female bed bugs.

From Zimbabwean Indigenous Knowledge: Scientific Substantiation of the Aphrodisiac Efficacy and Safety of Pittosporum viridiflorum in Male Rat Models

Introduction: Pittosporum viridiflorum, the multi habitat thriving plant species is widely believed to have been the source of sexual prowess for the polygamous kings and elites of the mighty medieval empire known as ‘Great Zimbabwe’. Despite the lack of systematic scientific validation, the macerated roots fractions continue to be the aphrodisiacs of choice among Zimbabweans.
 Aims: To scientifically validate the aphrodisiac claims using male rats’ sexual performance investigation protocols. To evaluate the toxicity profile and to identify the pharmacologically active metabolites present in the lyophilized hydro-ethanolic crude extracts.
 Methodology: Four concentrations of prepared Pittosporum viridiflorum root extract doses of 200, 400, 800 and 2000mg/kg as well as a commercial 5 mg/kg sildenafil citrate (standard) and distilled water (control) dosages were gavaged to male rats (n = 5 animals per group) for 21 days. The crude extract was subjected to screening protocols for various secondary metabolites of pharmacological relevance as well as acute oral toxicity profiling using OECD 425 TG. The sexual behaviour, mating parameters and hormonal changes in the male rats were evaluated accordingly.
 Observation and Results: Compared with the control, a significant increase in mating behaviour, mating performance and the serum hormonal levels were observed in test animals which showed a dose‑dependent bias. The phytoscreening evaluation confirmed the presence of saponins, phytosterols, flavonoids, di-terpenoids, tannins, and polyphenols. The Extract was toxicological safe with an LD50 above 2000mg/kg body weight.
 Conclusion: Pittosporum viridiflorum has excellent aphrodisiac activity on rats and is toxicologically safe for oral use. The abundant phytochemicals found are known to be pharmacologically active with regards to modulation of sexual hormones as well as sexual enhancement. It was further concluded that the traditional belief is valid, the plant can indeed be used as an alternative to modern medicines for various sexual dysfunctions and sexual performance enhancement.

Repeated sexual intercourse as a coping strategy for men with premature ejaculation.

Patients with premature ejaculation (PE) are often concerned and distressed about their sexual performance. Hence, they may be more willing to exploit their refractory period to employ sexual coping strategies in order to improve their unsatisfactory sexual intercourse compared with patients without PE. The study sought to verify the sexual coping strategies of patients with PE in the daily sexual activities. We included both patients with PE and individuals without PE and analyzed their sexual behaviors and attitudes by means of detailed interviews and questionnaires. The main outcomes were perceived intravaginal ejaculatory latency time recording, Premature Ejaculation Diagnostic Tool score, and sexual frequency, attitudes, and behavior log. A total of 182 young patients with PE (age 31.2 ± 6.2 years) and 92 individuals without PE (age 30.7 ± 5.1 years) were included in the study. A total of 53.3% of patients with PE vs 17.4% of individuals without PE reported engaging in multiple sexual intercourse sessions within a single day in the past 4 weeks. PE patients who engaged in multiple intercourse sessions displayed better performance during the second attempt but performed poorly compared with individuals without PE. Scores for the first attempt in PE vs second attempt in individuals with PE vs without PE were the following: intravaginal ejaculatory latency time, 2.4 ± 1.6 vs 4.8 ± 5.7 vs 9.9 ± 9.4 (P < .001); Premature Ejaculation Diagnostic Tool, 14.9 ± 3.1 vs 12.7 ± 4.8 vs 5.2 ± 2.5 (P < .001); satisfaction, 2.9 ± 1.0 vs 3.1 ± 0.8 vs 3.7 ± 1.4 (P < .001). A total of 57.1% of patients held a negative attitude toward precoital masturbation, for reasons such as a reduced sexual desire (21.2%), the belief that masturbation is harmful (17.6%), concerns about erectile function (15.7%), fatigue (9.8%), and other mixed reasons (35.3%). Engaging in multiple intercourse sessions within a day is more common among the young PE population, and using precoital masturbation as a coping strategy is not universally applicable among patients with PE. This is the first study to explore symptom-coping strategies in patients with PE compared with individuals without PE. However, the conclusions cannot be generalized to the entire male population. Patients with PE, compared with individuals without PE, are more inclined to engage in multiple sexual intercourse sessions within a single sexual session, likely in an attempt to compensate for their first unsatisfactory sexual encounter. Moreover, the majority of patients with PE here studied hold a negative attitude toward using precoital masturbation as a coping strategy for symptoms.