In this article, the problem of peristaltic transport of Carreau nanofluid with variable viscosity and heat source/sink through an inclined endoscope is debated. Nanofluid including the thermophoresis and Brownian motion effects are employed in the formulation of problem. Further the effects of wall properties and partial slip conditions are accounted. The problem is simplified under long wavelength and low Reynolds number approximations. Numerical computations are performed for velocity, temperature, concentration and heat transfer coefficient. Graphs reflecting the impacts of various physical parameters on flow properties are analyzed. It is notable that viscosity parameter gives rise to fluid velocity. Brownian diffusion parameter on temperature has qualitatively similar influence to that of thermophoresis parameter and Prandtl number. Nanoparticles mass transfer behaves oppositely for Brownian and thermophoresis parameter.