Effect of crystallographic orientation of nucleus on discontinuous dynamic recrystallization (DDRX) behavior in 304LN stainless steel is investigated using a multiscale model, namely a coupled crystal plasticity finite element method and DDRX-based cellular automata model. The three orientation selection schemes of nucleus are specially exploited in the simulation; i.e., (1) random orientation, (2) inheritance of orientation of parent deformed grain, and (3) generalized strain energy release maximization theory. The DDRX behaviors such as flow stress, DDRX volume fraction, grain size, and texture predicted by the three schemes are compared and the differences are explained through the simulated microstructure evolutions. This study suggests that it is reasonable to assign a random orientation to the nucleus through comparisons with experimental evidence.