Abstract The heat-source tower system has been evaluated in an enthalpy difference laboratory. This study analyzes the seasonal performance under various operating situations and fluid quality. In the summer and fall seasons, water is used as the circulating fluid in the tower. In the spring and winter seasons, glycol solution is used as the circulating fluid. Some parameters of the heat-source tower (e.g. the temperature of the solution inlet and outlet, the flow rate of the solution inlet and outlet, the temperature of the air inlet and outlet, the inlet air volume and the moisture content of the inlet air) are considered and measured to obtain its heat transfer characteristics. The simulation model of heat-source tower is constructed based on the mechanism of heat and mass transfer. This model is validated by the experimental results. The heat exchange and latent heat exchange of the system are analyzed under different parameters, as well as the variation law of inlet and outlet temperature and moisture content differences. The results show that the system has solution moisture absorption during winter operation. However, for every 9000 m3/h increase in air volume, the rate of solution dilution decreases between 9 and 43%. The rate of solution dilution is reduced by 11–31% for every 1°C in addition to the inlet solution temperature. Meanwhile, the heat dissipation in summer is about 2.8 times of the heat dissipation in winter.