<p class="abstract"><strong>Background: </strong>Microbiology, culture and sensitivity and antibiotic policy are ever changing in otolaryngology. So, it requires continuous research and modification.</p><p class="abstract"><strong>Methods: </strong>A retrospective study was conducted at our tertiary care center where microbiology and culture and sensitivity data of patients of chronic otitis media and neck abscess were assessed to form antibiotic policy for the concerned patients. The study comprised of 580 patients of chronic otitis media and 139 patients of neck abscess admitted from October 2018 to December 2019.</p><p class="abstract"><strong>Results: </strong><em>Pseudomonas</em> and <em>E. Coli </em>were the most common microbes isolated with most of cases sensitive to Meropenem and Amikacin respectively.</p><p class="abstract"><strong>Conclusions: </strong>There is a change in microbiological picture and sensitivity to a more resistant type than the previous studies and hence the requirement of modification of antibiotic policy to a more robust one.</p>
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