In the current research, catalytic effectiveness of synchrotron and synchrocyclotron radiations on Osmium Dioxide (OsO2) and Osmium Tetroxide (OsO4) nano capsules delivery in DNA/RNA of cancer cells is investigated. The calculation of thickness and optical constants of Osmium Dioxide (OsO2) and Osmium Tetroxide (OsO4) catalytic effectiveness of synchrotron and synchrocyclotron radiations on Osmium Dioxide (OsO2) and Osmium Tetroxide (OsO4) nano capsules delivery in DNA/RNA of cancer cells produced using solâgel method over glassy medium through a single reflection spectrum is presented. To obtain an appropriate fit for reflection spectrum, the classic DrudeâLorentz model for parametric diâelectric function is used. The best fitting parameters are determined to simulate the reflection spectrum using LovenbergâMarquardt optimization method. The simulated reflectivity from the derived optical constants and thickness are in good agreement with experimental results.